9 completed, 4 not yet recruiting, 3 recruiting, 3 unknown. 10 Not applicable, 5 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 10 | Not yet recruiting 4, Completed 3, Unknown 2, Recruiting 1 |
| Phase 4 | 5 | Completed 3, Recruiting 2 |
Follow Rebound Pain: new trials by email Literature Review of Rebound Pain trials Research Report on Rebound Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Continuous Interscalene Blocks and Rebound Pain Continuous interscalene nerve block, Interscalene Block - Total Shoulder Arthroplasty, Reverse Total Shoulder Arthroplasty | Not applicable | Not yet recruiting | University of Calgary | 154 | 2026-10-01 | 2026-08-19 |
| Nerve Block Resolution Time Display and Pain Complaints Physical display - Postoperative Pain, Rebound Pain | Not applicable | Not yet recruiting | Medical University of South Carolina | 128 | 2026-10-01 | 2026-10-21 |
| Intravenous Dexamethasone With Single-Shot Versus Continuous Brachial Plexus Block for Rebound Pain After Shoulder Surgery Dexamethasone (IV), Single-shot interscalene brachial plexus block, Continuous interscalene brachial plexus block - Pain, Postoperative, Rebound Pain | Phase 4 | Recruiting | Seoul National University Hospital | 92 | 2026-08-25 | 2026-09-29 |
| The Effect of Intravenous Dexketoprofen on the Severity and Incidence of Rebound Pain ISB + paracetamol IV 3*1, ISB+ paracetamol IV 3*1 +deksketoprofen IV 2*1 - Postoperative Pain, Pain Management | Not applicable | Recruiting | Eskisehir Osmangazi University | 66 | 2026-06-11 | 2026-06-12 |
| Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part A Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen - Post Operative Analgesia, Rebound Pain | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 100 | 2026-06-01 | 2026-06-24 |
| Prevention of Rebound Pain After Orthopaedic Surgery With Peripheral Nerve Block (REBOUND)_part B Morphine provided via oral PCA, Morphine provided via oral PCA + morphine administered at a scheduled regimen - Post Operative Analgesia, Rebound Pain | Not applicable | Not yet recruiting | Centre Hospitalier Universitaire Vaudois | 100 | 2026-06-01 | 2026-06-24 |
| Effect of Local Anesthetic Concentration on Rebound Pain Bupivacaine - Rebound Pain, Shoulder Arthroplasty | Phase 4 | Recruiting | University of Virginia | 10 | 2026-05-13 | 2026-09-09 |
| Comparison of Liposomal Bupivacaine Versus Ropivacaine in Alleviating Rebound Pain Liposomal Bupivicaine, ropivacaine - Rebound Pain, Liposomal Bupivacaine | Phase 4 | Completed | Liu Jiuhong | 100 | 2025-09-20 | 2026-06-24 |
| Rebound Pain After Peripheral Nerve Blocks in Total Knee Arthroplasty Total Knee Arthroplasty, Postoperative Pain | Completed | Konya City Hospital | 294 | 2025-05-21 | 2026-04-03 | |
| Heart Rate Variability as a Predictor of Rebound Pain Following Total Knee Arthroplasty Rebound Pain, Total Knee Arthroplasty | Completed | Konya City Hospital | 115 | 2025-05-20 | 2026-08-20 | |
| Ropivacaine Concentration and Rebound Pain Ropivacaine concentration low, Ropivacaine concentration high - Radius Fracture Distal, Rebound Pain | Phase 4 | Completed | Oslo University Hospital | 80 | 2025-02-14 | 2026-04-20 |
| Effect of Oliceridine on Rebound Pain No intervention - Rebound Pain, Arthroscopic Knee Surgery | Unknown | The First Affiliated Hospital of Xiamen University | 320 | 2024-01-01 | 2024-04-25 | |
| Rebound Pain Following Regional Anaesthesia for Ankle Fracture Surgery continuous infusion of levobupivacaine, oxycodone - Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Ankle Fracture - Lateral Malleolus | Phase 4 | Completed | University College Cork | 120 | 2023-10-16 | 2026-08-19 |
| The Effect of Intercostal Nerve Block With Dexamethasone and Ropivacaine on Rebound Pain After Thoracoscopic Surgery Dexamethasone 8mg+0.375% ropivacaine, 0.375% ropivacaine - Rebound Pain, Dexamethasone | Not applicable | Unknown | Beijing Tiantan Hospital | 260 | 2023-05-01 | 2023-04-24 |
| Regional and Intravenous Dexamethasone in The Prophylaxis of Rebound Pain After Supraclavicular Block in Upper Limb Surgeries Regional Dexamethasone, Intravenous Dexamethasone - Regional, Intravenous | Not applicable | Completed | Tanta University | 90 | 2023-03-01 | 2025-07-20 |
| Influence of Sensory Block Duration on Rebound Pain After Outpatient Foot Surgery Under Popliteal Sciatic Nerve Block. Rebound Pain, Sciatic Nerve Block | Completed | Hospital Universitario Doctor Peset | 107 | 2023-02-08 | 2024-12-04 | |
| Menstrual Cycle Effects on Postoperative Sensitivity and Rebound Pain in Composite Restorations Direct Posterior Composite Restoration - Postoperative Sensitivity, Rebound Pain | Not applicable | Completed | Firat University | 35 | 2022-08-01 | 2025-03-25 |
| The Effect of Intravenous Dexamethasone on Rebound Pain After Interscalene Brachial Plexus Block for Shoulder Surgery Group C, Group Dex - Rebound Pain | Not applicable | Completed | Karaman Training and Research Hospital | 60 | 2022-01-06 | 2022-06-01 |
| Local Anesthetic Concentration and Rebound Pain Reduced concentration of local anesthetic (ropivacaine), Usual concentration of local anesthetic (ropivacaine) - Rebound Pain | Not applicable | Unknown | Ajou University School of Medicine | 60 | 2020-07-10 | 2022-09-30 |
Pain, Postoperative (8) · Agnosia (5) · Acute Pain (1) · Ankle Fractures (1) · Fractures, Bone (1) · Rotator Cuff Injuries (1) · Shoulder Injuries (1) · Wrist Fractures (1)
Neurologic Manifestations (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Pain (8) · Pathologic Processes (8) · Postoperative Complications (8) · Nervous System Diseases (5) · Neurobehavioral Manifestations (5) · Perceptual Disorders (5) · Wounds and Injuries (4) · Fractures, Bone (2) · Ankle Injuries (1) · Arm Injuries (1) · Leg Injuries (1) · Rupture (1)
Ropivacaine (3) · Dexamethasone (2) · Bupivacaine (1) · Oxycodone (1)
Centre Hospitalier Universitaire Vaudois (2) · Konya City Hospital (2) · Ajou University School of Medicine (1) · Beijing Tiantan Hospital (1) · Eskisehir Osmangazi University (1) · Firat University (1) · Hospital Universitario Doctor Peset (1) · Karaman Training and Research Hospital (1) · Liu Jiuhong (1) · Medical University of South Carolina (1) · Oslo University Hospital (1) · Seoul National University Hospital (1) · Tanta University (1) · The First Affiliated Hospital of Xiamen University (1) · University College Cork (1)
Turkey (Türkiye) (5) · China (3) · South Korea (2) · Switzerland (2) · Canada (1) · Egypt (1) · Ireland (1) · Norway (1) · Spain (1) · United States (1)
Anette Aasen, MD, Anesthesiologist (1) · Brian D O'Donnell, MBBChBAO MSc FCARCSI MD (1) · In Kyong Yi, MD (1) · Javier Barrio, MD, PhD (1) · Jiuhong Liu (1) · Leon N Grinman, DO (1) · Mahmut Tutar, MD (1)