7 recruiting, 6 not yet recruiting, 2 active not recruiting, 1 completed. 9 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Recruiting 4, Not yet recruiting 2, Active not recruiting 1, Enrolling by invitation 1, Withdrawn 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow Pulsed Field Ablation: new trials by email Literature Review of Pulsed Field Ablation trials Research Report on Pulsed Field Ablation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pulsed Field Ablation for Paroxysmal Atrial Fibrillation: Clinical Efficacy and Left Atrial Function Protection Novel Pulsed Field Ablation System, Radiofrequency Ablation Catheter - Paroxysmal Atrial Fibrillation, Pulsed Field Ablation | Not applicable | Not yet recruiting | Tianjin Medical University General Hospital | 220 | 2026-10-01 | 2026-10-14 |
| Atrial Remodeling After PFA Substrate Modification for Persistent AF (PeAF) Pulsed-Field Ablation with FARAWAVE Catheter System - Persistent Atrial Fibrillation, Atrial Fibrillation (AF) | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 30 | 2026-07-01 | 2026-10-09 |
| OPTION-EMEA Clinical Trial Concomitant pulsed field ablation (PFA) and left atrial appendage closure (LAAC) during one interventional case, Concomitant Pulsed Field Ablation and Left Atrial Appendage Closure - Atrial Fibrillation (AF), Stroke Prevention in Patients With Atrial Fibrillation | Not applicable | Recruiting | Boston Scientific Corporation | 500 | 2026-06-18 | 2026-10-27 |
| Workflow Optimization During Pulse Field Ablation for Atrial Fibrillation lidocaine, Saline - Pulsed Field Ablation, Lidocaine | Phase 4 | Not yet recruiting | National Taiwan University Hospital | 60 | 2026-06-01 | 2026-04-20 |
| Evaluation of the Factors Associated With BRADYcardia Following Pulmonary Vein Isolation Using Pulsed Field Ablation Pulmonary vein isolation - Atrial Fibrillation (AF), Pulsed Field Ablation | Recruiting | Wroclaw Medical University | 100 | 2026-01-01 | 2026-09-09 | |
| Pulsed Field Ablation for Non-valvular Atrial Fibrillation After Left Atrial Appendage Occlusion Pulsed Field Ablation - Atrial Fibrillation, Left Atrial Appendage Occlusion | Not yet recruiting | First Affiliated Hospital of Ningbo University | 70 | 2025-12-01 | 2025-12-31 | |
| Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules Questionnaire - Thyroid Nodules, Pulsed Field Ablation | Recruiting | M.D. Anderson Cancer Center | 30 | 2025-11-14 | 2026-06-01 | |
| Comparative Intra-procedural Evaluation of Farapulse and FARAWAVE Nav Catheters Second-generation FARAWAVE Nav catheter without the use of pre-ablation CT, FARAPULSE with pre-ablation CT - Atrial Fibrillation (AF), Atrial Fibrillation Ablation | Not applicable | Recruiting | Cardiocentro Ticino | 58 | 2025-11-10 | 2026-03-19 |
| Spanish Registry of Redo Procedures Following Pulmonary Vein Ablation by Pulsed Field Ablation Technology: RESET-PFA Pulsed Field ablation: Ablation to treat atrial fibrillation - Cardiac Arrhythmia, Atrial Fibrillation | Not yet recruiting | Instituto de Investigación Sanitaria Aragón | 1100 | 2025-10-01 | 2025-09-22 | |
| Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation Pulsed field ablation of reccurent atrial arrythmia, Radiofrequency ablation of reccurent atrial arrythmia (standard of care) - Atrial Fibrillation (AF), Ablation Techniques | Not applicable | Recruiting | Wroclaw Medical University | 250 | 2025-08-30 | 2025-08-27 |
| A Registry on the FARAVIEW Technology of the OPAL HDx Mapping System When Used With the FARAWAVE NAV Ablation Catheter in the Treatment of Atrial Fibrillation FARAPULSE Pulsed Field Ablation System - Atrial Fibrillation, Pulsed Field Ablation | Active not recruiting | Boston Scientific Corporation | 550 | 2025-07-30 | 2026-10-23 | |
| Empiric Pulsed Field Pulmonary Vein Isolation During Atrial Tachycardia Ablation in Adults With Congenital Heart Disease Pulsed field ablation using a pentaspline ablation catheter - Atrial Fibrillation, Atrial Tachycardia | Not applicable | Withdrawn | Boston Children's Hospital | 2025-07-01 | 2026-07-14 | |
| 3D-Guided Pulsed Field Ablation for Paroxysmal AF pulsed field ablation - Atrial Fibrillation (AF), Pulsed Field Ablation | Not yet recruiting | Beijing Anzhen Hospital | 430 | 2025-06-30 | 2025-06-15 | |
| Pulsed Field Ablation Outcomes With Efficacy and Randomization in Atrial Fibrillation (POWER-AF) Pulsed field ablation, Radiofrequency ablation alone, Pulsed field ablation system - Atrial Fibrillation (AF), Atrial Fibrillation Ablation | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 1574 | 2025-04-16 | 2026-05-28 |
| Pulsed Field Ablation Versus Radiofrequency Ablation for Persistent Atrial Fibrillation Pulsed Field Ablation, Radiofrequency Ablation - Persistent Atrial Fibrillation, Radiofrequency Catheter Ablation | Not applicable | Not yet recruiting | Beijing Anzhen Hospital | 700 | 2025-02-15 | 2025-01-24 |
| 3-Dimensional Mapping System: The PULSTAR II Study Nanosecond pulsed electric field ablation system; Cardiac Pulsed Electric Field Ablation Catheter - Atrial Fibrillation (Paroxysmal), Paroxysmal AF | Not applicable | Active not recruiting | Shanghai Shangyang Medical Technology Co., Ltd. | 152 | 2024-10-10 | 2026-05-14 |
| Registry of Atrial Arrhythmia Ablation Procedures Using Pulsed Field Ablation in Poland PFA ablation procedure of atrial arrythmia - Atrial Fibrillation (AF), Atrial Flutter | Recruiting | Wroclaw Medical University | 500 | 2024-08-01 | 2025-08-07 | |
| PULSE PVC Registry: Multicenter Study on Focal Pulsed Field Ablation for Premature Ventricular Contractions Premature Ventricular Contraction (PVC), Pulsed Field Ablation | Completed | Zentralklinik Bad Berka | 200 | 2024-06-01 | 2026-09-10 |
Atrial Fibrillation (15) · Atrial Flutter (2) · Arrhythmias, Cardiac (1) · Atrial Remodeling (1) · Bradycardia (1) · Heart Defects, Congenital (1) · Thyroid Nodule (1) · Ventricular Premature Complexes (1)
Cardiovascular Diseases (16) · Heart Diseases (16) · Pathologic Processes (16) · Pathological Conditions, Signs and Symptoms (16) · Arrhythmias, Cardiac (15) · Cardiac Complexes, Premature (1) · Cardiac Conduction System Disease (1) · Cardiovascular Abnormalities (1) · Congenital Abnormalities (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Endocrine Gland Neoplasms (1) · Endocrine System Diseases (1) · Head and Neck Neoplasms (1) · Neoplasms (1) · Neoplasms by Site (1)
Radiofrequency Ablation (2) · Catheter Ablation (1) · Left Atrial Appendage Closure (1) · Lidocaine (1) · Sodium Chloride (1) · Standard of Care (1) · Surveys and Questionnaires (1)
Wroclaw Medical University (3) · Beijing Anzhen Hospital (2) · Boston Scientific Corporation (2) · Boston Children's Hospital (1) · Cardiocentro Ticino (1) · China National Center for Cardiovascular Diseases (1) · First Affiliated Hospital of Ningbo University (1) · Instituto de Investigación Sanitaria Aragón (1) · M.D. Anderson Cancer Center (1) · National Taiwan University Hospital (1) · Shanghai Shangyang Medical Technology Co., Ltd. (1) · Taipei Veterans General Hospital, Taiwan (1) · Tianjin Medical University General Hospital (1) · Zentralklinik Bad Berka (1)
China (4) · Poland (3) · Spain (3) · France (2) · Germany (2) · Italy (2) · Switzerland (2) · Taiwan (2) · Austria (1) · Belgium (1) · Croatia (1) · Greece (1) · Ireland (1) · Monaco (1) · Netherlands (1)
J. Christoph Geller, Prof. Dr. (1) · Santi Raffa, Dr. (1) · Victoria E Banuchi, MD (1)