3 recruiting, 1 completed. 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Recruiting 3, Completed 1 |
Follow Primary Prevention: new trials by email Literature Review of Primary Prevention trials Research Report on Primary Prevention
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification Pitavastatin 4mg and ezetimibe 10mg, taken once daily, Pitavastatin 2 mg with aspirin 100 mg, taken once daily. - Primary Prevention, Vascular Calcification | Phase 4 | Recruiting | Asan Medical Center | 7435 | 2025-07-09 | 2025-08-07 |
| LDL-C Optimization Using Inclisiran in Patients in Which Drug-Drug Interactions Limit LDL Lowering Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL - Drug Interactions, Primary Prevention | Phase 4 | Recruiting | University of California, San Diego | 100 | 2025-04-02 | 2026-11-10 |
| Clinical Comparison of Low-dose Rosuvastatin Plus Ezetimibe Combination Therapy and High-dose Rosuvastatin Monotherapy in Patients With Minimal to Intermediate Coronary Artery Disease Without Percutaneous Coronary Intervention Combination drug group of Ezetimibe 10 mg/Rosuvastatin 5 mg, Mono drug group of Rosuvastatin 20 mg - Coronary Artery Disease, Dyslipidemias | Phase 4 | Recruiting | Saint Vincent's Hospital, Korea | 6356 | 2024-02-01 | 2025-06-25 |
| Survival of Patients With Primary Prophylactic ICD Indication Intensified diagnostic and treatment measures following 1st appropriate ICD therapy, Standard follow-up - Primary Prevention, Tachycardia, Ventricular | Phase 4 | Completed | Biotronik SE & Co. KG | 504 | 2008-02-01 | 2015-01-12 |
Cardiovascular Diseases (1) · Coronary Artery Disease (1) · Death, Sudden, Cardiac (1) · Dyslipidemias (1) · Heart Failure (1) · Metabolic Syndrome (1) · Tachycardia, Ventricular (1) · Vascular Calcification (1) · Ventricular Fibrillation (1)
Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Cardiovascular Diseases (2) · Heart Diseases (2) · Arrhythmias, Cardiac (1) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Calcinosis (1) · Calcium Metabolism Disorders (1) · Cardiac Conduction System Disease (1) · Coronary Disease (1) · Death (1) · Death, Sudden (1) · Glucose Metabolism Disorders (1) · Heart Arrest (1)
ALN-PCS (1) · Aspirin (1) · Ezetimibe (1) · Rosuvastatin Calcium (1) · pitavastatin (1)
Asan Medical Center (1) · Biotronik SE & Co. KG (1) · Saint Vincent's Hospital, Korea (1) · University of California, San Diego (1)
South Korea (2) · Austria (1) · Czechia (1) · Germany (1) · Hungary (1) · Israel (1) · Latvia (1) · New Zealand (1) · Poland (1) · Slovakia (1) · Spain (1) · Switzerland (1) · United States (1)
Antoinette Birs, MD (1) · Edward Duran, MD (1) · Eric D Adler, MD (1) · Michael Wilkinson, MD (1) · Pam Taub, MD (1) · Robert Hatala, Prof. MUDr. (1) · Sung-ho Her, MD.PhD (1)