9 completed, 2 unknown, 1 recruiting, 1 terminated. 13 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 13 | Completed 9, Unknown 2, Recruiting 1, Terminated 1 |
Follow Prematurity: new trials by email Literature Review of Prematurity trials Research Report on Prematurity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Azithromycin and Ampicillin for Late PPROM Intravenous Ampicillin followed by Oral Amoxicillin, Ampicillin/Amoxicillin plus single-dose PO Azithromycin - Pregnancy Complications, Infectious, Premature Birth | Phase 4 | Recruiting | Sheba Medical Center | 311 | 2025-09-10 | 2025-12-18 |
| Late Preterm Corticosteroids and Neonatal Hypoglycemia Betamethasone Sodium Phosphate - Neonatal Hypoglycemia, Prematurity | Phase 4 | Unknown | University of Southern California | 210 | 2021-07-01 | 2021-05-03 |
| Effect of a Fortified Balanced Energy-Protein Supplement on Birth Outcome and Child Growth in Houndé District, Burkina Faso. Fortified balanced energy-protein (BEP) supplement, Fe and folic acid supplement - Small for Gestational Age at Delivery, Low Birth Weight | Phase 4 | Completed | University Ghent | 1788 | 2019-10-30 | 2022-03-22 |
| The Effect of Lipid Emulsions on Free Fatty Acids and Free Bilirubin in Premature Newborns Intralipid, 20% Intravenous Emulsion, Soybean oil Medium-chain triglycerides Olive oil Fish Oil (SMOF) lipid - Prematurity | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 66 | 2019-03-02 | 2025-03-03 |
| Apnea in Hospitalized Preterm Infants Following the Administration of Routine Childhood Vaccines PCV13, DTaP, HBV - Apnea, Apnea Neonatal | Phase 4 | Completed | Duke University | 223 | 2018-07-17 | 2024-02-14 |
| Babies Born Early Antibody Response to Men B Vaccination: BEAR Men B 4CMenB Vaccine - Prematurity, Vaccination | Phase 4 | Completed | St George's, University of London | 136 | 2017-08-01 | 2020-12-01 |
| Comparing HHHFNC and nCPAP Ventilation Methods for the Prevention of Extubation Failure in Preterm Infants Heated Humidified High-Flow Nasal Cannula - Extubation Failure, Prematurity | Phase 4 | Unknown | Zekai Tahir Burak Women's Health Research and Education Hospital | 200 | 2016-08-01 | 2016-09-13 |
| Clindamycin to Reduce Preterm Birth in a Low Resource Setting Clindamycin, Placebo - Pregnancy, Prematurity | Phase 4 | Completed | Christiana Care Health Services | 1726 | 2013-07-01 | 2016-07-18 |
| Supplementation With Lactoferrin in Preterm Newborns Lactoferrin - Prematurity, Low Birth Weight | Phase 4 | Completed | University of Siena | 1300 | 2011-01-01 | 2020-03-26 |
| Are Newborns Conscious of the Placebo Effect? Result From an RCT in Osteopathy Sham Osteopathic Manipulative Treatment, Standard care - Prematurity | Phase 4 | Completed | European Institute for Evidence Based Osteopathic Medicine | 250 | 2010-11-01 | 2013-05-13 |
| Effect of Osteopathic Manipulative Treatment on Length of Stay in Preterms osteopathic manipulative treatment, Usual care - Prematurity | Phase 4 | Completed | European Institute for Evidence Based Osteopathic Medicine | 100 | 2008-08-01 | 2012-03-05 |
| Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants Survanta (beractant), Curosurf (poractant) - Prematurity, Respiratory Distress Syndrome | Phase 4 | Terminated | Alan Fujii | 52 | 2005-01-01 | 2011-10-03 |
| Intermittent Preventive Treatment of Malaria in HIV-Seropositive Pregnant Women in Zambia Sulfadoxine-pyrimethamine (Fansidar) - Placental Malaria Infection, HIV Infections | Phase 4 | Completed | Center for International Health and Development | 454 | 2002-11-01 | 2006-01-31 |
Premature Birth (13) · Apnea (1) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Ductus Arteriosus, Patent (1) · HIV Infections (1) · HIV Seropositivity (1) · Hyperphagia (1) · Infant Nutrition Disorders (1) · Malaria (1) · Malaria, Falciparum (1) · Meningococcal Infections (1) · Perinatal Death (1) · Placenta Diseases (1) · Pregnancy Complications, Infectious (1) · Respiratory Distress Syndrome (1)
Female Urogenital Diseases and Pregnancy Complications (13) · Obstetric Labor Complications (13) · Obstetric Labor, Premature (13) · Pregnancy Complications (13) · Urogenital Diseases (13) · Infections (4) · Pathological Conditions, Signs and Symptoms (3) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · Genital Diseases (2) · Respiration Disorders (2) · Respiratory Tract Diseases (2) · Signs and Symptoms (2) · Blood-Borne Infections (1) · Cardiovascular Abnormalities (1)
4CMenB vaccine (1) · Amoxicillin (1) · Ampicillin (1) · BEP protocol (1) · Betamethasone (1) · Clindamycin (1) · Diphtheria-Tetanus-acellular Pertussis Vaccines (1) · Hepatitis B Vaccines (1) · Lactoferrin (1) · Lipids (1) · Manipulation, Osteopathic (1) · Poliovirus Vaccine, Inactivated (1) · Standard of Care (1) · beractant (1) · betamethasone sodium phosphate (1)
European Institute for Evidence Based Osteopathic Medicine (2) · Alan Fujii (1) · Center for International Health and Development (1) · Christiana Care Health Services (1) · Duke University (1) · Sheba Medical Center (1) · St George's, University of London (1) · The University of Texas Health Science Center, Houston (1) · University Ghent (1) · University of Siena (1) · University of Southern California (1) · Zekai Tahir Burak Women's Health Research and Education Hospital (1)
United States (4) · Italy (2) · Burkina Faso (1) · India (1) · Israel (1) · United Kingdom (1) · Zambia (1)
Francesco Cerritelli, DO, MS (2) · Alan M Fujii, MD (1) · Andrea Trembath, MD (1) · Brenda PH de Kok, MSc. (1) · Carl Lachat, Prof. dr. (1) · Cody Arnold, MD (1) · Davidson H Hamer, MD (1) · Karen Broder, MD (1) · Katrien W Vanslambrouck, MD (1) · Laeticia Celine Toe, MD MSc. (1) · Lieven F Huybregts, PhD (1) · Mary A Staat, MD (1) · Matthew K Hoffman, MD MPH (1) · Noa Gonen, MD (1) · Patrick Kolsteren, Prof. dr. (1)
PMID 18008241, PMID 19956811, PMID 20336076, PMID 20336077, PMID 23622070, PMID 33762226, PMID 34494113, PMID 35524695, PMID 35560315, PMID 35906874, PMID 36745684, PMID 37486952, PMID 38977298, PMID 39324693, PMID 39761016, PMID 40652683
2017 (1)