6 completed, 2 terminated, 2 unknown, 1 withdrawn. 4 Phase 2, 4 Phase 3, 3 Not applicable, 3 Phase 4, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 3, Unknown 1 |
| Phase 3 | 4 | Completed 2, Terminated 1, Unknown 1 |
| Not applicable | 3 | Completed 2, Withdrawn 1 |
| Phase 4 | 3 | Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
Follow beractant: new trials by email Literature Review of beractant trials Research Report on beractant
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Goat Lung Surfactant for the Treatment of Respiratory Distress Syndrome in Preterm Neonates Cadisurf, Survanta - Respiratory Distress Syndrome | Phase 2 / Phase 3 | Unknown | Ramesh K Agarwal | 900 | 2016-06-01 | 2016-05-17 |
| Aerosolized Surfactant in Neonatal RDS Surfactant - Respiratory Distress Syndrome, Newborn | Phase 1 / Phase 2 | Completed | Sood, Beena G., MD, MS | 159 | 2014-12-01 | 2021-08-25 |
| Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress Syndrome Curosurf®, Survanta® - Respiratory Distress Syndrome | Not applicable | Withdrawn | University of Michigan | 2012-06-01 | 2014-01-08 | |
| Effects of Bolus Surfactant Therapy on Peripheral Perfusion Index and Tissue Carbon Monoxide exogenous surfactant - Respiratory Distress Syndrome | Phase 4 | Completed | Ege University | 48 | 2012-03-01 | 2013-08-16 |
| Perfusion Index Variability in Respiratory Distress Syndrome Beractant, Poractant alfa - Poor Peripheral Perfusion | Not applicable | Completed | Dr. Sami Ulus Children's Hospital | 92 | 2011-08-01 | 2013-05-13 |
| Comparison of Two Different Natural Surfactants in the Treatment of Pulmonary Hemorrhage Poractant alfa, Beractant - Pulmonary Hemorrhage | Not applicable | Completed | Dr. Sami Ulus Children's Hospital | 20 | 2010-03-01 | 2013-05-22 |
| Prevention of Chronic Lung Disease (CLD) in Preterm Infants budesonide, surfactant and air (placebo) - Respiratory Distress Syndrome, Chronic Lung Disease of Prematurity | Phase 4 | Unknown | China Medical University, China | 300 | 2009-04-01 | 2012-08-08 |
| A Multicenter, Randomized, Open Label Trial of a New Animal Extracted Surfactant to Treat RDS in Preterm Infants Butantan, Control - Respiratory Distress Syndrome | Phase 2 / Phase 3 | Completed | University of Sao Paulo | 327 | 2005-04-01 | 2014-12-02 |
| Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants Survanta (beractant), Curosurf (poractant) - Prematurity, Respiratory Distress Syndrome | Phase 4 | Terminated | Alan Fujii | 52 | 2005-01-01 | 2011-10-03 |
| Early Surfactant to Reduce Use of Mechanical Breathing in Low Birth Weight Infants Early surfactant, Standard practice - Infant, Newborn, Respiratory Distress Syndrome | Phase 3 | Terminated | NICHD Neonatal Research Network | 61 | 2000-05-01 | 2015-06-08 |
| Exosurf Neonatal and Survanta for Treatment of Respiratory Distress Syndrome Exosurf, Survanta - Infant, Newborn, Infant, Low Birth Weight | Phase 2 / Phase 3 | Completed | NICHD Neonatal Research Network | 617 | 1991-01-01 | 2019-03-22 |
Respiratory Distress Syndrome (8) · Premature Birth (4) · Bronchopulmonary Dysplasia (2) · Ductus Arteriosus, Patent (1) · Respiratory Distress Syndrome, Newborn (1) · Respiratory Insufficiency (1)
Dr. Sami Ulus Children's Hospital (2) · NICHD Neonatal Research Network (2) · Alan Fujii (1) · China Medical University, China (1) · Ege University (1) · Ramesh K Agarwal (1) · Sood, Beena G., MD, MS (1) · University of Michigan (1) · University of Sao Paulo (1)
United States (5) · Turkey (Türkiye) (2) · Brazil (1) · China (1)
Avroy A. Fanaroff, MD (2) · Barbara J. Stoll, MD (2) · Charles R. Bauer, MD (2) · David K. Stevenson, MD (2) · Edward F. Donovan, MD (2) · James A. Lemons, MD (2) · Jon E. Tyson, MD MPH (2) · Seetha Shankaran, MD (2) · Sheldon B. Korones, MD (2) · Alan M Fujii, MD (1) · Alexander R Precioso, MD PhD (1) · Beena G. Sood, MD, MS (1) · Celso M Rebello, MD PhD (1) · Dilek Dilli, Assoc Prof (1) · Elizabeth C. Wright, PhD (1)
PMID 19956811, PMID 20336076, PMID 20336077, PMID 25628188, PMID 26351971, PMID 31485014, PMID 33338661, PMID 8095608, PMID 8229487
U10HD021364 (2), U10HD021385 (2), U10HD021397 (2), U10HD021415 (2), U10HD027851 (2), U10HD027853 (2), U10HD027856 (2), U10HD027871 (2), U10HD027880 (2), U10HD027881 (2), M01RR000070 (1), M01RR000750 (1), M01RR000997 (1), M01RR001032 (1), M01RR006022 (1)