62 completed, 24 unknown, 7 recruiting, 6 not yet recruiting. 34 Not applicable, 24 Phase 3, 20 Phase 2, 11 Phase 1, 4 Phase 4.
Follow Premature Ejaculation: new trials by email Literature Review of Premature Ejaculation trials Research Report on Premature Ejaculation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Male Pelvic Floor Muscle Rehabilitation Exercises Male Pelvic Floor Rehabilitation #1 - Erectile Dysfunction, Urinary Incontinence | Not applicable | Not yet recruiting | Dream Video LLC | 100 | 2026-12-01 | 2026-10-07 |
| Evaluate the Efficacy and Safety of VV913 Capsules in the Treatment of PE VV913 2mg Capsules, VV913 5mg Capsules, VV913 10mg Capsules - Premature Ejaculation | Phase 2 | Not yet recruiting | Vigonvita Life Sciences | 500 | 2026-08-31 | 2026-07-23 |
| Effect of Prostatic Urethra and Seminal Vesicle Morphometry on Ejaculation Premature Ejaculation, Ejaculation | Not yet recruiting | Başakşehir Çam & Sakura City Hospital | 150 | 2026-05-10 | 2026-06-03 | |
| Impact of Depression Severity on Sexual Dysfunction Depression, Erectile Dysfunction | Active not recruiting | Sohag University | 100 | 2026-05-01 | 2026-06-04 | |
| Pelvic Floor Therapies for Lifelong Premature Ejaculation Electromagnetic Pelvic Floor Stimulation, Biofeedback-Assisted Pelvic Floor Muscle Training, Conventional Pelvic Floor Muscle Training - Premature Ejaculation, Lifelong Premature Ejaculation | Not applicable | Recruiting | Tanta University | 150 | 2026-04-26 | 2026-06-04 |
| The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation control, exercise - Erectile Dysfunction, Premature Ejaculation | Not applicable | Recruiting | Uskudar University | 50 | 2026-03-01 | 2026-03-03 |
| Dorsal Penile Nerve Cryoneurolysis for Lifelong PE Percutaneous Dorsal Penile Nerve Cryoneurolysis, Sertraline (Oral Antidepressant), Tadalafil 5 mg - Premature Ejaculation | Not applicable | Completed | Biruni University | 117 | 2026-02-04 | 2026-10-16 |
| Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized Study Botulinum toxin type A, Hyaluronic acid - Premature Ejaculation | Not applicable | Not yet recruiting | Benha University | 80 | 2025-12-15 | 2025-11-19 |
| Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE) KH-001 ODT, Placebo ODT - Premature Ejaculation | Phase 2 | Recruiting | Kadence Bio | 40 | 2025-12-01 | 2026-08-12 |
| Vagus Nerve Stimulation in Premature Ejaculation Transcutaneous Auricular Vagus Nerve Stimulation - Premature Ejaculation | Not applicable | Completed | Bahçeşehir University | 102 | 2025-12-01 | 2026-06-04 |
| Comparison of the Efficacy and Safety of Dapoxetine, Kegel Exercises, and Acupuncture in the Treatment of Premature Ejaculation: A Randomized, Double-Blind, Placebo-Controlled Trial serotonin reuptake inhibitor (SSRI), Placebo, Acupuncture - Premature Ejaculation | Not applicable | Not yet recruiting | Medipol University | 250 | 2025-10-01 | 2025-07-16 |
| Silicone Band Versus Prilocaine Spray for Lifelong Premature Ejaculation Frenular Silicone Band, Prilocaine 10% Spray - Premature Ejaculation | Not applicable | Completed | Başakşehir Çam & Sakura City Hospital | 32 | 2025-09-15 | 2026-09-15 |
| Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination Therapy Versus Monotherapy Paroxetine 20 Mg Oral Tablet - Premature Ejaculation | Not applicable | Not yet recruiting | South Valley University | 60 | 2025-07-01 | 2025-07-09 |
| Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial Detecting Brain Activity with Functional Near Infrared Spectroscopy - Premature Ejaculation | Not applicable | Unknown | Xijing Hospital | 20 | 2025-04-08 | 2025-04-17 |
| THE IMPACT OF VITAMIN B12 TREATMENT ON EJACULATORY FUNCTIONS IN MEN: SYMPTOMATIC RELIEF AND IMPROVED OUTCOMES Vitamin B12 - Premature Ejaculation | Completed | OZGUR EKICI | 54 | 2024-10-01 | 2025-06-25 | |
| Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men Destress and Perform Capsule-U001, Destress and Perform Capsule-I001, Placebo capsules 002 - Premature Ejaculation, Stress | Not applicable | Unknown | Herbolab India Pvt. Ltd. | 60 | 2024-09-05 | 2024-08-26 |
| Safety and Efficacy of Botulinum Toxin-A Injection Into Ischiocavernosus Muscle for Premature Ejaculation 25 units botox, 50 units Botox, 75 units Botox - Premature Ejaculation | Phase 2 / Phase 3 | Active not recruiting | Abdallah Mohamed Abdallah Mohamed Elgendy | 45 | 2024-07-01 | 2025-02-28 |
| Efficacy and Safety of Toronto Association in the Treatment of Erectile Dysfunction and Premature Ejaculation Toronto association, Tadalafil, Tadalafil placebo - Erectile Dysfunction, Premature Ejaculation | Phase 3 | Unknown | EMS | 232 | 2024-07-01 | 2023-04-12 |
| Comparative Evaluation of Safety and Efficacy of Dapoxetine, Silodosin, and Citalopram in the Management of Premature Ejaculation Oral intake of medication - Premature (Early) Ejaculation | Phase 4 | Completed | Beni-Suef University | 450 | 2024-06-01 | 2025-08-08 |
| Ejaculatory and Orgasmic Dysfunction Registry Ejaculatory Dysfunction, Premature Ejaculation | Recruiting | Charitable Union for the Research and Education of Peyronie's Disease | 500 | 2024-05-30 | 2026-08-26 |
Showing 20 of 106. Sign in to see all of them.
Sexual Dysfunction, Physiological (20) · Erectile Dysfunction (18) · Sexual Dysfunctions, Psychological (8) · Coitus (7) · Premature Birth (7) · Ejaculatory Dysfunction (2) · Anxiety Disorders (1) · Asthenia (1) · Depression (1) · Masturbation (1) · Prostatitis (1) · Sexual Behavior (1) · Urinary Incontinence (1)
Genital Diseases (106) · Genital Diseases, Male (106) · Male Urogenital Diseases (106) · Mental Disorders (106) · Urogenital Diseases (106) · Ejaculatory Dysfunction (104) · Sexual Dysfunctions, Psychological (98) · Sexual Dysfunction, Physiological (86) · Behavior (10) · Female Urogenital Diseases and Pregnancy Complications (8) · Sexual Behavior (8) · Obstetric Labor Complications (7) · Obstetric Labor, Premature (7) · Pregnancy Complications (7) · Pathological Conditions, Signs and Symptoms (2)
dapoxetine (20) · Sildenafil Citrate (5) · Tadalafil (5) · Exercise (4) · Paroxetine (4) · Clomipramine (3) · Tramadol (3) · Behavior Therapy (2) · Botulinum Toxins, Type A (2) · Hyaluronic Acid (2) · Lidocaine (2) · Lidocaine, Prilocaine Drug Combination (2) · Prilocaine (2) · Saline Solution (2) · Tablets (2)
GlaxoSmithKline (6) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (5) · Sohag University (5) · Boston Medical Group (4) · Janssen Research & Development, LLC (4) · Plethora Solutions Ltd (4) · Alza Corporation, DE, USA (3) · Cairo University (3) · Instituto Sexológico Murciano (3) · Virility Medical Ltd. (3) · Xijing Hospital (3) · Ankara Training and Research Hospital (2) · Assiut University (2) · Bahçeşehir University (2) · Bausch Health Americas, Inc. (2)
Egypt (14) · Turkey (Türkiye) (14) · United States (13) · China (10) · South Korea (9) · Spain (5) · United Kingdom (5) · Australia (4) · France (4) · Colombia (3) · Israel (3) · Italy (3) · Mexico (3) · Poland (3) · Austria (2)
Ilan Gruenwald, MD (3) · Mohammed Abu El-Hamd, MD (2) · Abdelraouf Elmohsen, Professor (1) · Ahmed Elshahid, Professor (1) · Ahmed L Elsayed, MD (1) · Alejandro Molina Cabeza, MD (1) · Ali Veysel Ozden, PhD,MD (1) · Annelize Koch, Dr (1) · Baibing Yang, Doctor (1)
PMID 21059176, PMID 16962882, PMID 20412423, PMID 21889833, PMID 24883105, PMID 16934919, PMID 17352514, PMID 18391557, PMID 18466262, PMID 18498422, PMID 19195772, PMID 19245438, PMID 19878447, PMID 20367770, PMID 21050394, PMID 21256670, PMID 22320846, PMID 23636274, PMID 23651451, PMID 23845016, PMID 23937679, PMID 24453509, PMID 24572995, PMID 24848805, PMID 25130949, PMID 25356301, PMID 25356302, PMID 26552599, PMID 27049323, PMID 27652216, PMID 29516873, PMID 30419940, PMID 30705437, PMID 31148903, PMID 31351659, PMID 31351660, PMID 32037229, PMID 32791039, PMID 36897239, PMID 39057551, PMID 41327131
2009 (1), 2023 (1)