12 completed, 4 unknown, 1 active not recruiting, 1 not yet recruiting. 20 Phase 2, 3 Phase 3, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 20 | Completed 12, Unknown 4, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 3 | 3 | Completed 2, Active not recruiting 1 |
| Phase 1 | 2 | Completed 2 |
Follow Premature Ejaculation: new trials by email Literature Review of Premature Ejaculation trials Research Report on Premature Ejaculation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluate the Efficacy and Safety of VV913 Capsules in the Treatment of PE VV913 2mg Capsules, VV913 5mg Capsules, VV913 10mg Capsules - Premature Ejaculation | Phase 2 | Not yet recruiting | Vigonvita Life Sciences | 500 | 2026-08-31 | 2026-07-23 |
| Study to Evaluate the Potential Effects of KH-001 on Intravaginal Ejaculatory Latency Time (IELT), Patient-Reported Outcomes, and Safety in Men With Lifelong Premature Ejaculation (LPE) KH-001 ODT, Placebo ODT - Premature Ejaculation | Phase 2 | Recruiting | Kadence Bio | 40 | 2025-12-01 | 2026-08-12 |
| Safety and Efficacy of Botulinum Toxin-A Injection Into Ischiocavernosus Muscle for Premature Ejaculation 25 units botox, 50 units Botox, 75 units Botox - Premature Ejaculation | Phase 2 / Phase 3 | Active not recruiting | Abdallah Mohamed Abdallah Mohamed Elgendy | 45 | 2024-07-01 | 2025-02-28 |
| On-demand Silodosin 4mg vs Dapoxetine 60mg in Treatment of Primary Premature Ejaculation sildosin 4mg, dapoxetine 60mg - Premature (Early) Ejaculation | Phase 2 / Phase 3 | Completed | Benha University | 95 | 2024-03-01 | 2025-07-23 |
| Sildenafil Added Effect in Dapoxetine Non-responding Mono-symptomatic Premature Ejaculation (PE) Sildenafil 50 mg Oral Tablet and Dapoxitine 3mg Oral tablet, Placebo oral tablet and Dapoxitine 3mg Oral tablet - Premature Ejaculation | Phase 2 | Unknown | Al-Azhar University | 200 | 2022-10-01 | 2022-09-27 |
| Brain Networks Implicated in Lifelong Premature Ejaculation Patients Transcranial Radom Noise Stimulation, Take Dapoxetine, Comparation EEG changes between Sham Group against tRNS and Dapoxetin participants - Premature Ejaculation, Sexual Dysfunction | Phase 1 / Phase 2 | Completed | Moises Domingo | 128 | 2021-02-02 | 2023-04-12 |
| PSD502 in Subjects With Premature Ejaculation Placebo, PSD502 - Premature Ejaculation | Phase 2 | Completed | Plethora Solutions Ltd | 121 | 2018-12-26 | 2022-07-05 |
| Effectiveness and Tolerability of Lidocaine 5% Spray in Treatment of Lifelong Premature Ejaculation Patients. Lidocaine 5% spray, Placebo - Lidocaine Spray | Phase 2 | Completed | Sohag University | 150 | 2018-04-20 | 2019-10-07 |
| IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT), Patient Reported Outcomes and Safety in Men With Premature Ejaculation (PE) IX-01 400 mg, Placebo, IX-01 800 mg - Premature Ejaculation | Phase 2 | Completed | Ixchelsis Limited | 239 | 2017-02-28 | 2019-10-07 |
| A Phase 2 Study of On-demand Therapy With Clomipramine and Sildenafil Combination in Premature Ejaculation CDFR0812-15/25mg, CDFR0812-15/50mg, Condencia - Premature Ejaculation | Phase 2 | Unknown | CTC Bio, Inc. | 297 | 2015-11-01 | 2015-12-17 |
| IX-01 Effect on Intravaginal Ejaculatory Latency Time (IELT) and Patient Reported Outcomes in Men With Premature Ejaculation (PE) IX-01, Placebo - Premature Ejaculation | Phase 2 | Completed | Ixchelsis Limited | 88 | 2014-09-01 | 2020-08-17 |
| Safety and Efficacy of Silodosin in the Treatment of Premature Ejaculation Silodosin, Placebo - Premature Ejaculation | Phase 2 | Unknown | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | 40 | 2013-10-01 | 2016-01-05 |
| A Safety and Efficacy Study of OnabotulinumtoxinA in Premature Ejaculation OnabotulinumtoxinA, Normal Saline - Premature Ejaculation | Phase 2 | Terminated | Allergan | 59 | 2013-08-07 | 2018-10-18 |
| Clinical Trial to Evaluate the Efficacy and Safety of DA-8031 in Male Patients With Premature Ejaculation DA-8031, Placebo - Premature Ejaculation | Phase 2 | Unknown | Dong-A Pharmaceutical Co., Ltd. | 220 | 2013-01-01 | 2013-08-15 |
| Safety, Tolerability, Pharmacokinetics and Efficacy of YHD1044 dapoxetine - Premature Ejaculation | Phase 1 / Phase 2 | Completed | Yuhan Corporation | 24 | 2011-02-01 | 2012-08-01 |
| Phase 2 Trial of PED-1 and PED-2 in Male Patients With Premature Ejaculation Clomipramine - Premature Ejaculation | Phase 2 | Completed | Symyoo | 104 | 2010-09-01 | 2012-10-03 |
| A Study To Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Oral Doses of GSK557296 in a Study in Men With Premature Ejaculation GSK557296, placebo - Premature Ejaculation | Phase 2 | Completed | GlaxoSmithKline | 77 | 2009-12-23 | 2017-09-12 |
| Efficacy, Safety and Tolerability of PSD502 (a Topical Anesthetic) in the Treatment Premature Ejaculation PSD502, contains a mixture of lidocaine and prilocaine, Placebo - Premature Ejaculation | Phase 2 / Phase 3 | Completed | Plethora Solutions Ltd | 256 | 2007-10-01 | 2016-09-26 |
| A Study On Concentrations Of 16448 In Blood And The Safety Of This Compound In Healthy Males With Premature Ejaculation 16448 - Premature Ejaculation | Phase 2 | Completed | GlaxoSmithKline | 18 | 2006-12-01 | 2012-03-19 |
| Exploratory Study of Pagoclone in Men With Premature Ejaculation. pagoclone - Premature Ejaculation | Phase 2 | Completed | Endo USA Inc., a Keenova Therapeutics Company | 100 | 2006-07-01 | 2013-12-27 |
Sexual Dysfunction, Physiological (2) · Coitus (1) · Premature Birth (1)
Ejaculatory Dysfunction (20) · Genital Diseases (20) · Genital Diseases, Male (20) · Male Urogenital Diseases (20) · Mental Disorders (20) · Sexual Dysfunctions, Psychological (20) · Urogenital Diseases (20) · Sexual Dysfunction, Physiological (18) · Behavior (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Obstetric Labor Complications (1) · Obstetric Labor, Premature (1) · Pregnancy Complications (1) · Sexual Behavior (1)
Lidocaine, Prilocaine Drug Combination (2) · dapoxetine (2) · Botulinum Toxins, Type A (1) · Clomipramine (1) · DA 8031 (1) · Lidocaine (1) · MG 50-3-1 (1) · Prilocaine (1) · Saline Solution (1) · Sildenafil Citrate (1) · Tablets (1) · epelsiban (1) · pagoclone (1) · silodosin (1)
GlaxoSmithKline (2) · Ixchelsis Limited (2) · Plethora Solutions Ltd (2) · Abdallah Mohamed Abdallah Mohamed Elgendy (1) · Al-Azhar University (1) · Allergan (1) · Benha University (1) · CTC Bio, Inc. (1) · Dong-A Pharmaceutical Co., Ltd. (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Kadence Bio (1) · Moises Domingo (1) · Sohag University (1) · Symyoo (1) · Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation (1)
United States (7) · South Korea (4) · Egypt (3) · Australia (2) · China (1) · Ireland (1) · Netherlands (1) · Spain (1) · Taiwan (1) · United Kingdom (1)
Abdelraouf Elmohsen, Professor (1) · Ahmed Elshahid, Professor (1) · Alejandro Molina Cabeza, MD (1) · Cheng-Hsing Hsieh, MD (1) · Culley Carson, MD (1) · Dae Yul Yang (1) · Daniel Radecki (1) · Du Geon Moon (1) · Hui Jiang (1) · Hwan-Seok Choi, M.D, Ph.D. (1) · Jae-Seung Paick (1) · Jed Kaminetsky, MD, BA (1) · Jong Kwan Park (1)