20 completed, 6 unknown, 4 not yet recruiting, 3 recruiting. 34 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 34 | Completed 20, Unknown 6, Not yet recruiting 4, Recruiting 3, Terminated 1 |
Follow Premature Ejaculation: new trials by email Literature Review of Premature Ejaculation trials Research Report on Premature Ejaculation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Male Pelvic Floor Muscle Rehabilitation Exercises Male Pelvic Floor Rehabilitation #1 - Erectile Dysfunction, Urinary Incontinence | Not applicable | Not yet recruiting | Dream Video LLC | 100 | 2026-12-01 | 2026-10-07 |
| Pelvic Floor Therapies for Lifelong Premature Ejaculation Electromagnetic Pelvic Floor Stimulation, Biofeedback-Assisted Pelvic Floor Muscle Training, Conventional Pelvic Floor Muscle Training - Premature Ejaculation, Lifelong Premature Ejaculation | Not applicable | Recruiting | Tanta University | 150 | 2026-04-26 | 2026-06-04 |
| The Effectiveness of Exercise in the Treatment of Erectile Dysfunction and Premature Ejaculation control, exercise - Erectile Dysfunction, Premature Ejaculation | Not applicable | Recruiting | Uskudar University | 50 | 2026-03-01 | 2026-03-03 |
| Dorsal Penile Nerve Cryoneurolysis for Lifelong PE Percutaneous Dorsal Penile Nerve Cryoneurolysis, Sertraline (Oral Antidepressant), Tadalafil 5 mg - Premature Ejaculation | Not applicable | Completed | Biruni University | 117 | 2026-02-04 | 2026-10-16 |
| Hyaluronic Acid vs Botulinum Toxin Injection in Treatment of Lifelong Drug-Resistant Premature Ejaculation: Randomized Study Botulinum toxin type A, Hyaluronic acid - Premature Ejaculation | Not applicable | Not yet recruiting | Benha University | 80 | 2025-12-15 | 2025-11-19 |
| Vagus Nerve Stimulation in Premature Ejaculation Transcutaneous Auricular Vagus Nerve Stimulation - Premature Ejaculation | Not applicable | Completed | Bahçeşehir University | 102 | 2025-12-01 | 2026-06-04 |
| Comparison of the Efficacy and Safety of Dapoxetine, Kegel Exercises, and Acupuncture in the Treatment of Premature Ejaculation: A Randomized, Double-Blind, Placebo-Controlled Trial serotonin reuptake inhibitor (SSRI), Placebo, Acupuncture - Premature Ejaculation | Not applicable | Not yet recruiting | Medipol University | 250 | 2025-10-01 | 2025-07-16 |
| Silicone Band Versus Prilocaine Spray for Lifelong Premature Ejaculation Frenular Silicone Band, Prilocaine 10% Spray - Premature Ejaculation | Not applicable | Completed | Başakşehir Çam & Sakura City Hospital | 32 | 2025-09-15 | 2026-09-15 |
| Therapeutic Outcomes of Selective Serotonin Reuptake Inhibitors and Phosphodiesterase-5 Inhibitors Combination Therapy Versus Monotherapy Paroxetine 20 Mg Oral Tablet - Premature Ejaculation | Not applicable | Not yet recruiting | South Valley University | 60 | 2025-07-01 | 2025-07-09 |
| Brain Activity During Sexual Behavior in Patients With Primary Premature Ejaculation a Clinical Trial Detecting Brain Activity with Functional Near Infrared Spectroscopy - Premature Ejaculation | Not applicable | Unknown | Xijing Hospital | 20 | 2025-04-08 | 2025-04-17 |
| Clinical Study to Reduce Premature Ejaculation in Healthy Adult Men Destress and Perform Capsule-U001, Destress and Perform Capsule-I001, Placebo capsules 002 - Premature Ejaculation, Stress | Not applicable | Unknown | Herbolab India Pvt. Ltd. | 60 | 2024-09-05 | 2024-08-26 |
| The Study on the Effectiveness and Safety of Electroacupuncture at ST36 in Treating Primary Premature Ejaculation Electroacupuncture at ST36 - Premature Ejaculation | Not applicable | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 35 | 2024-01-01 | 2024-01-16 |
| A Comparative Study of Selective Dorsal Neurectomy, Pulsed Radiofrequency Neuromodulation, and Intragranular Hyaluronic Acid Injection for Premature Ejaculation Microscopic Selective Dorsal Neurectomy (SDN), Pulsed Radiofrequency (PRF) Nerve Ablation, Intraglanular Hyaluronic Acid (HA) Injection - Premature Ejaculation | Not applicable | Completed | Ahmed Hamdy Ahmed | 30 | 2022-07-01 | 2025-01-22 |
| Precise Use of Lidocaine Cream to Treat Primary Premature Ejaculation Lidocaine cream - Premature Ejaculation | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 80 | 2022-03-01 | 2023-03-01 |
| Effect of Respiratory Exercises On The Intravaginal Ejaculation Latency Time Pelvic floor exercises and behavioral therapy, Respiratory exercises - Premature Ejaculation | Not applicable | Completed | Bahçeşehir University | 59 | 2022-01-10 | 2023-02-02 |
| Transcutaneous Electrical Nerve Stimulation for the Treatment of Premature Ejaculation transcutaneous posterior tibial nerve stimulation - Transcutaneous Electrical Nerve Stimulation, Premature Ejaculation | Not applicable | Completed | Cairo University | 50 | 2022-01-01 | 2024-10-26 |
| Dual-Site Botulinum Toxin Type A Injection for Lifelong Premature Ejaculation BoNT-A, Placebo injection (normal saline) - Premature (Early) Ejaculation | Not applicable | Completed | Al Mouwasat Hospital | 150 | 2021-11-01 | 2026-03-17 |
| Effectiveness of Pelvic Floor Therapy for the Management of Erectile Dysfunction and Premature Ejaculation. Therapeutic exercises, Perineal electromyographic biofeedback, Electrical stimulation - Erectile Dysfunction, Premature (Early) Ejaculation | Not applicable | Recruiting | Boston Medical Group | 66 | 2021-10-30 | 2026-01-23 |
| The Effect of Behavioral Therapy Given to Men and Their Partners' Behavioral Therapy - Premature Ejaculation, Sexual Function Disturbances | Not applicable | Completed | University of Gaziantep | 84 | 2021-06-30 | 2023-07-28 |
| Transcutaneous Posterior Tibial Nerve Stimulation for Premature Ejaculation Transcutaneous posterior tibial nerve stimulation, Paroxetine - Premature Ejaculation | Not applicable | Completed | Boston Medical Group | 120 | 2020-07-15 | 2026-05-12 |
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Erectile Dysfunction (4) · Sexual Dysfunction, Physiological (4) · Premature Birth (3) · Asthenia (1) · Ejaculatory Dysfunction (1) · Masturbation (1) · Sexual Dysfunctions, Psychological (1) · Urinary Incontinence (1)
Genital Diseases (34) · Genital Diseases, Male (34) · Male Urogenital Diseases (34) · Mental Disorders (34) · Urogenital Diseases (34) · Ejaculatory Dysfunction (33) · Sexual Dysfunctions, Psychological (33) · Sexual Dysfunction, Physiological (30) · Female Urogenital Diseases and Pregnancy Complications (4) · Obstetric Labor Complications (3) · Obstetric Labor, Premature (3) · Pregnancy Complications (3) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Behavior (1)
Exercise (3) · Behavior Therapy (2) · Paroxetine (2) · dapoxetine (2) · Acupuncture Therapy (1) · Antidepressive Agents (1) · Blood Specimen Collection (1) · Botulinum Toxins, Type A (1) · Breathing Exercises (1) · Electric Stimulation (1) · Exercise Therapy (1) · Hyaluronic Acid (1) · Injections (1) · Lubricants (1) · Prilocaine (1)
Boston Medical Group (3) · Instituto Sexológico Murciano (3) · Virility Medical Ltd. (3) · Bahçeşehir University (2) · Abant Izzet Baysal University (1) · Ahmed Hamdy Ahmed (1) · Al Mouwasat Hospital (1) · Ankara Training and Research Hospital (1) · Başakşehir Çam & Sakura City Hospital (1) · Benha University (1) · Biruni University (1) · Cairo University (1) · Dream Video LLC (1) · Herbolab India Pvt. Ltd. (1) · Institut National de la Santé Et de la Recherche Médicale, France (1)
Turkey (Türkiye) (8) · Egypt (5) · China (4) · Colombia (3) · Israel (3) · France (2) · Spain (2) · Italy (1) · Saudi Arabia (1)
Ilan Gruenwald, MD (3) · Ali Veysel Ozden, PhD,MD (1) · Baibing Yang, Doctor (1) · Cristina Amaya (1) · Dilber Karagozoglu Coskunsu, PhD,PT (1) · Dr. Ramshyam Agarwal, MBBS, DNB (1) · Haitham Abdalla Shello, MD (1) · Kubra Erkut, PT (1)
PMID 16934919, PMID 17352514, PMID 18391557, PMID 18498422, PMID 21050394, PMID 21059176, PMID 21256670, PMID 23651451, PMID 24848805, PMID 24883105, PMID 25356302, PMID 26552599, PMID 27049323, PMID 27652216, PMID 29516873, PMID 30419940, PMID 31148903, PMID 32037229, PMID 32791039, PMID 36897239