3 completed, 2 not yet recruiting, 1 active not recruiting, 1 recruiting. 3 Not applicable, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 3 | Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 3 | 3 | Completed 2, Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
Follow Postoperative Depression: new trials by email Literature Review of Postoperative Depression trials Research Report on Postoperative Depression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Delivery Mode Impact on Postoperative Depression Postoperative Depression | Not yet recruiting | Jingping Wang, MD, Ph.D. | 4000 | 2026-10-15 | 2026-06-09 | |
| Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery. Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose - Cardio-pulmonary Bypass, Cardiovascular Diseases | Not applicable | Not yet recruiting | Nicosia General Hospital | 108 | 2026-09-01 | 2026-05-13 |
| Feasibility of Breathwork Intervention With Older Adults After Knee Surgery A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video - Surgical Stress Response, Stress Physiological | Not applicable | Recruiting | University of Arizona | 32 | 2026-07-01 | 2026-07-06 |
| REmotely-delivered Supportive Programs for Improving Surgical Pain and disTrEss eHealth Mindful Movement and Breathing, Life Impacts Reflection, PROMIS Questionnaires - Postoperative Pain, Acute, Postoperative Depression | Phase 3 | Active not recruiting | Wake Forest University Health Sciences | 160 | 2023-06-13 | 2026-07-24 |
| The Impact of Preoperative Chronic Pain on Postoperative Depressive States in Elderly Patients Undergoing Joint Replacement Surgery: A Secondary Analysis Based on Prospective Data Postoperative Depression | Completed | Chinese PLA General Hospital | 575 | 2022-04-30 | 2026-02-11 | |
| Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial Ketamine, Normal saline - Postoperative Depression | Phase 3 | Completed | Washington University School of Medicine | 32 | 2022-04-25 | 2026-08-21 |
| Intravenous Esketamine on Prevention of Postoperative Depression in Patients Undergoing Cardiac Surgery Esketamine, Normal saline - Postoperative Depression | Not applicable | Unknown | Anshi Wu | 80 | 2021-12-01 | 2021-12-14 |
| Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy Ketamine, Placebo Comparator - Pain, Postoperative Depression | Phase 2 / Phase 3 | Completed | NYU Langone Health | 90 | 2014-10-01 | 2020-03-16 |
Pain, Postoperative (3) · Anxiety Disorders (1) · Cardiovascular Diseases (1) · Pain (1) · Parasomnias (1) · Postoperative Complications (1) · Stress, Psychological (1)
Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Pain (3) · Pathologic Processes (3) · Postoperative Complications (2) · Behavior (1) · Behavioral Symptoms (1) · Mental Disorders (1) · Nervous System Diseases (1) · Sleep Wake Disorders (1)
Ketamine (3) · Saline Solution (2) · Ascorbic Acid (1) · Esketamine (1) · Lactulose (1) · Lignin (1) · Respiration (1) · Sodium Chloride (1)
Anshi Wu (1) · Chinese PLA General Hospital (1) · Jingping Wang, MD, Ph.D. (1) · NYU Langone Health (1) · Nicosia General Hospital (1) · University of Arizona (1) · Wake Forest University Health Sciences (1) · Washington University School of Medicine (1)
United States (4) · China (2) · Cyprus (1)
Anshi Wu Wu, Ph.D (1) · Athanasios D. Athanasiou, MD, MSc, MPA (1) · Devon E Cobos Garcia, PhD Candidate (1) · Elpidoforos S. Soteriades, MD, Ass Prof (1) · Jing Wang, MD, PHD (1) · Ruth E Taylor-Piliae, PhD (1) · Stephanie J Sohl, PhD (1) · Thaddeus W W Pace, PhD (1) · Weidong MI Mi, PHD (1)
PMID 19111491, PMID 25169982, PMID 30095550, PMID 32111231, PMID 37483552, PMID 38179107
R01CA266995 (1)