18 completed. 18 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 18 | Completed 18 |
| Phase 1 | 3 | Completed 3 |
| Phase 3 | 1 | Completed 1 |
Follow Post Traumatic Stress Disorder: new trials by email Literature Review of Post Traumatic Stress Disorder trials Research Report on Post Traumatic Stress Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| An Evaluation of the Safety and Efficacy of Methylone for the Treatment of PTSD Methylone - Post Traumatic Stress Disorder | Phase 2 | Completed | Transcend Therapeutics | 62 | 2024-04-04 | 2025-11-25 |
| An Evaluation of the Long-term Efficacy and Safety of Methylone for the Treatment of PTSD Methylone - Post Traumatic Stress Disorder | Phase 2 | Completed | Transcend Therapeutics | 44 | 2024-03-06 | 2025-11-25 |
| MDMA for AUD/PTSD Comorbidity MDMA - Alcohol Use Disorder, Post Traumatic Stress Disorder | Phase 2 | Completed | Carolina L Haass-Koffler | 22 | 2024-02-06 | 2026-09-11 |
| A Study to Assess the Use of Methylone in the Treatment of PTSD Methylone, Placebo - Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Transcend Therapeutics | 79 | 2023-03-01 | 2026-04-15 |
| The Safety and Tolerability of COMP360 in Participants With Post-traumatic Stress Disorder Psilocybin - Post Traumatic Stress Disorder | Phase 2 | Completed | COMPASS Pathways | 22 | 2022-06-10 | 2025-06-13 |
| Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin Oxytocin nasal spray, Brief Cognitive-Behavioral Conjoint Therapy - Post Traumatic Stress Disorder, Relational Problems | Phase 2 | Completed | San Diego Veterans Healthcare System | 20 | 2022-01-17 | 2023-07-10 |
| Stellate Ganglion Block to Augment Trauma-focused Therapy Among Veterans With PTSD Cognitive Processing Therapy (CPT), Stellate Ganglion Block - PTSD, Trauma and Stressor Related Disorders | Phase 2 | Completed | Ohio State University | 85 | 2022-01-03 | 2025-07-03 |
| A Study of JZP150 in Adults With Posttraumatic Stress Disorder JZP150, Placebo - Post Traumatic Stress Disorder | Phase 2 | Completed | Jazz Pharmaceuticals | 282 | 2021-12-29 | 2024-12-31 |
| ALTO-100 in MDD and/or PTSD ALTO-100 PO tablet - Major Depressive Disorder, Post Traumatic Stress Disorder | Phase 2 | Completed | Alto Neuroscience | 245 | 2021-12-20 | 2023-12-01 |
| A Phase 2 Open-Label Treatment Development Study of MDMA-Assisted Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder (PTSD) MDMA - Post Traumatic Stress Disorder | Phase 2 | Completed | Remedy | 10 | 2021-10-04 | 2024-11-14 |
| MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD 3,4-methylenedioxymethamphetamine - Post Traumatic Stress Disorder, Combat Stress Disorders | Phase 2 | Completed | VA Loma Linda Health Care System | 5 | 2021-07-29 | 2025-07-20 |
| Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans Lofexidine, Placebo oral tablet - Post Traumatic Stress Disorder, Opioid-use Disorder | Phase 2 | Completed | Pharmacotherapies for Alcohol and Substance Use Disorders Alliance | 84 | 2021-03-09 | 2026-05-08 |
| Probiotic (LGG) for Veterans With PTSD Lactobacillus rhamnosus GG (LGG; ATCC strain 53103; CRMTS #11272; PTS #3766), Placebo - Post Traumatic Stress Disorder, Inflammation | Phase 2 | Completed | VA Eastern Colorado Health Care System | 383 | 2020-08-24 | 2026-03-24 |
| Burnout and Distress preventiOn With caNnabidiol in Front-line Health Care workerS deAling wIth COVID-19 Cannabidiol - Covid19, Burn Out | Phase 2 / Phase 3 | Completed | University of Sao Paulo | 120 | 2020-06-16 | 2021-09-28 |
| Cannabidiol as a Treatment for AUD Comorbid With PTSD Cannabidiol, Placebos - Alcohol Use Disorder, Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | NYU Langone Health | 95 | 2019-09-16 | 2023-06-28 |
| Exploring Nitrous Oxide Effects for Post Traumatic Stress Disorder (PTSD) Nitrous Oxide - Post Traumatic Stress Disorder | Phase 2 | Completed | Stanford University | 3 | 2018-04-01 | 2020-07-24 |
| Stress Reduction in Middle Eastern Refugees Narrative Exposure Therapy - Post Traumatic Stress Disorder | Phase 2 | Completed | Wayne State University | 63 | 2010-12-01 | 2013-06-17 |
| Deep Transcranial Magnetic Stimulation (TMS)- Treatment for Post Traumatic Stress Disorder Deep repetitive Transcranial Magnetic Stimulation (rTMS) real or sham - Post Traumatic Stress Disorder | Phase 1 / Phase 2 | Completed | Hadassah Medical Organization | 30 | 2008-02-01 | 2015-04-21 |
Stress Disorders, Post-Traumatic (18) · Alcoholism (2) · Burnout, Psychological (1) · COVID-19 (1) · Combat Disorders (1) · Depressive Disorder, Major (1) · Inflammation (1) · Narration (1) · Opioid-Related Disorders (1) · Psychological Trauma (1) · Trauma and Stressor Related Disorders (1) · Wounds and Injuries (1)
Mental Disorders (18) · Stress Disorders, Traumatic (18) · Trauma and Stressor Related Disorders (17) · Chemically-Induced Disorders (3) · Substance-Related Disorders (3) · Alcohol-Related Disorders (2) · Behavior (2) · Behavioral Symptoms (1) · Communication (1) · Coronaviridae Infections (1) · Coronavirus Infections (1) · Depressive Disorder (1) · Infections (1) · Lung Diseases (1) · Mood Disorders (1)
N-Methyl-3,4-methylenedioxyamphetamine (3) · methylone (3) · Cannabidiol (2) · Nitrous Oxide (1) · Oxytocin (1) · Psilocybin (1) · Transcranial Magnetic Stimulation (1) · lofexidine (1)
Transcend Therapeutics (3) · Alto Neuroscience (1) · COMPASS Pathways (1) · Carolina L Haass-Koffler (1) · Hadassah Medical Organization (1) · Jazz Pharmaceuticals (1) · NYU Langone Health (1) · Ohio State University (1) · Pharmacotherapies for Alcohol and Substance Use Disorders Alliance (1) · Remedy (1) · San Diego Veterans Healthcare System (1) · Stanford University (1) · University of Sao Paulo (1) · VA Eastern Colorado Health Care System (1) · VA Loma Linda Health Care System (1)
United States (15) · United Kingdom (4) · Ireland (2) · Australia (1) · Brazil (1) · Canada (1) · Israel (1)
Alison Bruni, MD (1) · Anne Wagner, PhD (1) · Carolyn Rodriguez, MD, PhD (1) · Charles Marmar, MD (1) · Christopher D. Verrico, PhD (1) · Craig J Bryan, PsyD (1) · Jose A. Crippa, MD; PhD (1) · Leslie Morland, PsyD (1) · Lisa Brenner, Ph.D. (1) · Mark A Lumley, Ph.D (1) · Moshe Isserles, MD, MSc (1) · Shannon Remick, MD (1) · Thomas R Kosten, MD (1)
PMID 22921765, PMID 32609959, PMID 34387679, PMID 39262902, PMID 39719161, PMID 40883964, PMID 41497513, PMID 41706459, PMID 42460632