4 completed, 2 active not recruiting, 2 recruiting, 2 terminated. 4 Phase 4, 3 Phase 1, 3 Phase 3, 1 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 3, Withdrawn 1 |
| Phase 1 | 3 | Terminated 2, Unknown 1 |
| Phase 3 | 3 | Active not recruiting 2, Recruiting 1 |
| Not applicable | 1 | Completed 1 |
Follow Peripheral Nervous System Agents: new trials by email Literature Review of Peripheral Nervous System Agents trials Research Report on Peripheral Nervous System Agents
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU) NT 201, NT 201 Placebo - Neuromuscular Agents, Peripheral Nervous System Agents | Phase 3 | Active not recruiting | Merz Aesthetics GmbH | 300 | 2025-10-01 | 2026-09-10 |
| A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in the United States NT 201, NT 201 Placebo - Neuromuscular Agents, Peripheral Nervous System Agents | Phase 3 | Active not recruiting | Merz North America, Inc. | 300 | 2025-08-27 | 2026-09-10 |
| Nebulized Ketamine for the Treatment of Major Depressive Disorder nebulized ketamine, nebulized midazolam - Severe Depression, Moderate Depression | Phase 3 | Recruiting | Theresa Jacob, PhD, MPH | 40 | 2024-10-16 | 2026-04-24 |
| Natural History of Depression, Bipolar Disorder and Suicide Risk Behavioral Symptoms, Suicide | Recruiting | National Institute of Mental Health (NIMH) | 500 | 2024-09-09 | 2026-10-01 | |
| Oral Aspirin + Ketamine as Adjunct to Oral Antidepressant Therapy for Depression VTS-K - Treatment Resistant Depression, Major Depressive Disorder | Phase 4 | Completed | Theresa Jacob, PhD, MPH | 15 | 2022-12-06 | 2026-04-21 |
| Rescue Quadratus Lumborum Blocks for Post-cesarean Pain Saline, Bupivacaine, Dexamethasone - Morphine, Analgesics | Phase 4 | Withdrawn | The University of Texas Health Science Center, Houston | 2022-01-01 | 2023-11-03 | |
| Transversus Abdominis Plan Block, Ultrasound or Laparoscopic? bupivacaine - Bupivacaine, Anesthetics, Local | Not applicable | Completed | Ankara City Hospital Bilkent | 60 | 2020-11-01 | 2021-01-28 |
| Natural Killer Cell (CYNK-001) IV Infusion or IT Administration in Adults With Recurrent GBM CYNK001-IV, CYNK001-IT - Astrocytoma, Grade IV, Giant Cell Glioblastoma | Phase 1 | Terminated | Celularity Incorporated | 3 | 2020-10-01 | 2022-08-10 |
| Natural Killer Cell (CYNK-001) Infusions in Adults With Multiple Myeloma CYNK-001 - Multiple Myeloma, Neoplasm, Plasma Cell | Phase 1 | Unknown | Celularity Incorporated | 29 | 2020-05-12 | 2023-02-16 |
| Natural Killer Cell (CYNK-001) Infusions in Adults with AML CYNK-001 - Leukemia, Leukemia, Myeloid | Phase 1 | Terminated | Celularity Incorporated | 27 | 2020-03-12 | 2024-12-12 |
| Evaluation of Abdominal Wall Block With Liposomal Bupivacaine for Post-Operative Analgesia in Donor Nephrectomy Abdominal wall block with liposomal bupivicaine - Pain, Postoperative, Analgesics, Opioid | Phase 4 | Completed | University of California, Los Angeles | 146 | 2018-01-01 | 2022-01-10 |
| Determination of Minimum Effective Volume of Local Anesthetic in Patients Undergoing Ultrasound-Guided Infraclavicular Approach for Brachial Plexus Blockade Procedure/Surgery: bupivakain % 0,5 - Underdosing of Local Anesthetics, Anesthetics, Local | Phase 4 | Completed | Ankara City Hospital Bilkent | 48 | 2015-11-01 | 2021-10-27 |
Depression (3) · Depressive Disorder, Major (2) · Depressive Disorder, Treatment-Resistant (2) · Hematologic Diseases (2) · Neoplasm, Residual (2) · Neoplasms (2) · Neoplasms by Histologic Type (2) · Pain, Postoperative (2) · Agnosia (1) · Behavioral Symptoms (1) · Bipolar Disorder (1) · Blood Protein Disorders (1) · Cardiovascular Diseases (1) · Depressive Disorder (1) · Glioblastoma (1)
Pathological Conditions, Signs and Symptoms (5) · Behavior (4) · Pathologic Processes (4) · Neurologic Manifestations (3) · Signs and Symptoms (3) · Behavioral Symptoms (2) · Hemic and Lymphatic Diseases (2) · Mental Disorders (2) · Mood Disorders (2) · Neoplastic Processes (2) · Postoperative Complications (2) · Astrocytoma (1) · Bipolar and Related Disorders (1) · Depressive Disorder (1) · Glioma (1)
Bupivacaine (2) · Ketamine (2) · incobotulinumtoxinA (2) · Aspirin (1) · Dexamethasone (1) · Midazolam (1) · Sodium Chloride (1)
Celularity Incorporated (3) · Ankara City Hospital Bilkent (2) · Theresa Jacob, PhD, MPH (2) · Merz Aesthetics GmbH (1) · Merz North America, Inc. (1) · National Institute of Mental Health (NIMH) (1) · The University of Texas Health Science Center, Houston (1) · University of California, Los Angeles (1)
United States (9) · France (1) · Germany (1) · Poland (1) · Puerto Rico (1) · Spain (1) · Turkey (Türkiye) (1)
Theresa Jacob, PhD, MPH (2) · Adrian Kilcoyne, MD (1) · Elizabeth D Ballard, Ph.D. (1) · Linden Lee, MD (1) · Sharmila Koppisetti, M.D (1) · Sharmila Koppisetti, MD (1) · Siamak Rahman, MD (1)