65 completed, 7 terminated, 4 recruiting, 4 unknown. 26 Phase 4, 18 Phase 1, 18 Phase 3, 14 Phase 2, 8 Not applicable.
Follow Cetirizine: new trials by email Literature Review of Cetirizine trials Research Report on Cetirizine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| DV Plus Toripalimab With Cetirizine and Mecobalamin Pretreatment in Patients With Locally Advanced Unresectable or Metastatic Bladder Cancer Disitamab Vedotin, Toripalimab, Cetirizine - Bladder Cancer | Phase 1 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 20 | 2027-01-01 | 2026-10-01 |
| Alternate Pre-med in Anti-Cluster of Differentiation 20 (CD20) Pilot Project Cetirizine, Diphenhydramine - Multiple Sclerosis | Phase 3 | Not yet recruiting | University of Miami | 60 | 2026-11-01 | 2026-10-02 |
| Comparing Standard-Dose and High-Dose Cetirizine for Acute Urticaria Cetirizine 10 mg once daily, Cetirizine 20 mg twice daily, total 40 mg/day - Acute Urticaria | Not applicable | Recruiting | University of Phayao | 140 | 2025-11-15 | 2026-10-05 |
| Relative Bioavailability Study to Evaluate Cetirizine HCl Gummy 10 mg and Cetirizine HCl Oral Tablets 10 mg cetirizine HCl Gummy, Zyrtec tablet 10mg - Allergy | Phase 1 | Unknown | Seattle Gummy Company | 30 | 2025-05-01 | 2024-06-13 |
| The Treatment of Moderate to Severe Allergic Rhinitis With Electroacupuncture Combined With Microneedle Knife Electroacupuncture combined with Microneedle Knife, Cetirizine hydrochloride tablets combined with nasal budesonide spray. - Allergic Rhinitis (Disorder), Electroacupuncture | Not applicable | Recruiting | Pengfei Qiu | 90 | 2025-04-11 | 2025-03-30 |
| The Impact of Airway Allergic Diseases on Children's and Parents' Quality of Life Subcutaneous immunotherapy / Standard Treatment for Asthma and Rhinitis - Pediatric Asthma, Rhinitis, Allergic | Recruiting | Wenjing Zhou | 600 | 2024-07-20 | 2024-08-02 | |
| Phase III Clinical Study of Cetirizine Hydrochloride Injection in Treatment of Acute Urticaria Cetirizine Hydrochloride Injection, Diphenhydramine Hydrochloride Injection - Acute Urticaria | Phase 3 | Recruiting | Shandong New Time Pharmaceutical Co., LTD | 284 | 2024-04-22 | 2025-02-11 |
| Treatment of Long CoronaVirus Disease (COVID) (TLC) Feasibility Trial Cetirizine, Famotidine, Cetirizine Placebo - COVID-19 | Phase 3 | Terminated | Emory University | 5 | 2024-03-08 | 2025-07-17 |
| Organ Protective Effect of Cetirizine In Patients With Severe Burns Cetirizine, Midazolam and Fentanyl - Burns | Phase 1 / Phase 2 | Unknown | Ruijin Hospital | 32 | 2024-01-23 | 2024-02-01 |
| A Prospective Study to Investigate Safety and Tolerability of Shorter Infusion of Fabrazyme AGALSIDASE BETA (GZ419828), Acetaminophen, Diphenhydramine - Fabry's Disease | Phase 4 | Completed | Sanofi | 8 | 2023-11-10 | 2025-10-21 |
| Microneedling-Assisted Delivery of Cetirizine Versus Latanoprost in Alopecia Areata Cetirizine (Zyrtec), Latanoprost, Triamcinolone Acetonide - Microneedling-Assisted Delivery, Cetirizine | Not applicable | Completed | Tanta University | 80 | 2022-10-01 | 2026-08-11 |
| The Effect of Switching the H1-antagonist Clemastine to Cetirizine in Premedication Regimens During Paclitaxel Treatment Cetirizine, Clemastine IV - Solid Tumor | Completed | Erasmus Medical Center | 395 | 2022-06-01 | 2024-09-25 | |
| Safety, Tolerability, and Pharmacokinetics of UX053 in Patients With Glycogen Storage Disease Type III (GSD III) UX053, Placebo, Antipyretic - Glycogen Storage Disease Type III | Phase 1 / Phase 2 | Terminated | Ultragenyx Pharmaceutical Inc | 9 | 2021-10-18 | 2024-04-16 |
| Cetirizine and Famotidine for COVID-19 Cetirizine and Famotidine, Placebo - Covid19 | Phase 4 | Withdrawn | Emory University | 2021-08-01 | 2021-08-20 | |
| The Effect of Cetirizine HCl on Exercise-induced Arterial Hypoxemia in Highly-trained Swimmers Cetirizine HCl, Placebo - Exercise-induced Arterial Hypoxemia | Phase 4 | Terminated | Indiana University | 16 | 2021-05-19 | 2024-03-05 |
| Efficacy of Antihistamine Drugs as Medical Expulsive Therapy Alone or in Combination With Alpha Blockers: A Prospective Randomized Controlled Study Tamsulosin, Cetirizine, Cetirizine + Tamsulosin - Lower Ureteric Stones | Phase 3 | Completed | South Valley University | 480 | 2021-03-01 | 2024-12-31 |
| Topical Cetirizine in Androgenetic Alopecia in Females Topical cetirizine, Placebo, Topical minoxidil - Androgenetic Alopecia | Phase 2 / Phase 3 | Completed | Cairo University | 66 | 2020-07-25 | 2023-02-08 |
| Topical Cetirizine 1% vs Minoxidil 5% Gel in Treatment of Androgenetic Alopecia Cetirizine, Minoxidil - Androgenetic Alopecia | Phase 4 | Unknown | Assiut University | 60 | 2020-06-01 | 2020-03-04 |
| Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V Diphenhydramine Cetirizine HCl 10 mg/mL, Diphenhydramine 50 mg/mL, anti-CD20 such as Rituximab or Paclitaxel - Oncology Patients Receiving Chemotherapy | Phase 2 | Completed | TerSera Therapeutics LLC | 34 | 2020-03-25 | 2023-10-06 |
| Feasibility of a Clinical Trial Comparing the Use of Cetirizine to Replace Diphenhydramine in the Prevention of Reactions Related to Paclitaxel Diphenhydramine, Cetirizine, Lactose pill - Breast Cancer, Lung Cancer | Phase 3 | Completed | Ciusss de L'Est de l'Île de Montréal | 27 | 2020-02-14 | 2020-10-12 |
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Rhinitis, Allergic, Seasonal (19) · Rhinitis, Allergic (14) · Hypersensitivity (9) · Rhinitis, Allergic, Perennial (6) · Rhinitis (5) · Urticaria (5) · Asthma (3) · Alopecia (2) · COVID-19 (2) · Dermatitis (2) · Multiple Sclerosis (2) · Pruritus (2) · Alopecia Areata (1) · Altitude Sickness (1) · Breast Neoplasms (1)
Organon and Co (9) · GlaxoSmithKline (8) · Faes Farma, S.A. (3) · UCB Pharma (3) · Actavis Inc. (2) · Dr. Reddy's Laboratories Limited (2) · Emory University (2) · Idorsia Pharmaceuticals Ltd. (2) · Indiana University (2) · Mylan Pharmaceuticals Inc (2) · Ranbaxy Laboratories Limited (2) · Aciex Therapeutics, Inc. (1) · Arrowhead Pharmaceuticals (1) · Assiut University (1) · Bayer (1)
United States (31) · Canada (9) · China (5) · Egypt (4) · Germany (4) · Japan (3) · Netherlands (3) · Austria (2) · Spain (2) · Australia (1) · Belgium (1) · Colombia (1) · France (1) · Italy (1) · Poland (1)
Charu Gautam, MD (2) · Janine North, B.S. (2) · So Ran Hong, M.D. (2) · Anne K Ellis, MD (1) · David Bernstein, MD (1) · Dial Hewlett, MD (1) · Donald W Cockcroft, MD (1) · Douglas B Tzanetos, M.D. (1) · Elisabeth Kruse, PhD (1) · Eric Sicard, MD (1) · Eugene Protzko, MD (1)
PMID 28392807, PMID 19438584, PMID 19943178, PMID 21810005, PMID 22077106, PMID 22341813, PMID 23282979, PMID 23420231, PMID 23806461, PMID 24686526, PMID 24708643, PMID 24726923, PMID 26108088, PMID 27326985, PMID 27536452, PMID 28709817, PMID 29371864, PMID 29440045, PMID 34536239, PMID 34555839, PMID 34997314, PMID 35001564, PMID 35123074, PMID 35953455, PMID 36571611, PMID 36843581, PMID 38280453, PMID 38420865, PMID 38642709, PMID 38848522, PMID 41907282, PMID 42547470
2004 (1), 2014 (1), R01DK083609 (1)