22 completed, 9 unknown, 4 recruiting, 1 active not recruiting. 9 Not applicable, 7 Phase 4, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 9 | Recruiting 4, Completed 2, Unknown 2, Active not recruiting 1 |
| Phase 4 | 7 | Completed 4, Unknown 3 |
| Phase 2 | 2 | Completed 1, Terminated 1 |
Follow Normal Tension Glaucoma: new trials by email Literature Review of Normal Tension Glaucoma trials Research Report on Normal Tension Glaucoma
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness Clinical observation, diagnostic testing - Normal Tension Glaucoma, Obstructive Sleep Apnea | Not yet recruiting | Northwell Health | 100 | 2025-09-02 | 2025-06-10 | |
| Transcorneal Electrical Stimulation for the Treatment of Visual Field Defects in Patients With Open-Angle Glaucoma Transcorneal electrical stimulation (TES) with the OkuStim 2 System - Glaucoma, Primary Open Angle Glaucoma | Not applicable | Recruiting | Okuvision GmbH | 50 | 2025-04-02 | 2026-03-12 |
| Effect of Netarsudil vs Brimonidine in NTG Patients on Latanoprost Netarsudil, Brimonidine - Normal Tension Glaucoma | Phase 4 | Completed | Westlake Eye Specialists | 100 | 2024-06-13 | 2025-10-22 |
| R&D of Non-invasive Innovative Intracranial Waves Monitoring System for Diagnostics and Treatment Monitoring of Patients with Normal Tension Glaucoma Monitoring of cerebral hemodynamics - Normal Tension Glaucoma | Unknown | Lithuanian University of Health Sciences | 156 | 2024-04-22 | 2024-10-09 | |
| Direct Selective Laser Trabeculoplasty in Ethnic Chinese Population External Automatic Glaucoma Laser, Direct Selective Laser Trabeculoplasty - Primary Open Angle Glaucoma, Ocular Hypertension | Not applicable | Active not recruiting | BelkinVision | 40 | 2024-03-11 | 2026-08-17 |
| EVALUATION of CATS TONOMETER PRISM in LASIK SUBJECTS This is observational IOP measurement - Glaucoma, Ocular Hypertension | Completed | Intuor Technologies, Inc. | 198 | 2024-02-12 | 2024-11-05 | |
| Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma Trabeculectomy, Deep Sclerectomy - Normal Tension Glaucoma | Not applicable | Recruiting | Helsinki University Central Hospital | 80 | 2022-05-31 | 2024-03-15 |
| Study in Prostaglandin Associated Peri-orbitopathy Switching From Prostaglandin Monotherapy to Omidenepag Isopropyl Eybelis ophthalmic solution 0.002% - Normal Tension Glaucoma, Primary Open-angle Glaucoma | Phase 4 | Unknown | Santen Pharmaceutical Asia Pte. Ltd. | 150 | 2022-02-15 | 2022-03-15 |
| Water Drinking Test Study and Disc Hemorrhages in Normal Tension Glaucoma water drinking test - Normal Tension Glaucoma | Not applicable | Unknown | University of Manitoba | 20 | 2021-10-01 | 2021-10-12 |
| Intraocular Pressure Reduction Efficacy of Rhopressa and Lumigan in Normal Tension Glaucoma Netarsudil Ophthalmic, Bimatoprost Ophthalmic - Normal Tension Glaucoma | Phase 4 | Unknown | Salus University | 115 | 2021-08-01 | 2021-08-06 |
| Endoscopic Cyclophotocoagulation in Normal Tension Glaucoma Phaco, Phaco+ECP - Normal Tension Glaucoma, Cataract | Not applicable | Recruiting | Helsinki University Central Hospital | 100 | 2020-12-08 | 2020-12-22 |
| Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics Corneal biomechanics (Corvis ST, Oculus, Wetzlar, Germany), Corneal topography and tomography (Pentacam, Oculus, Wetzlar, Germany), Optic nerve head measurement - Corneal Ectasia, Corneal Disease | Completed | Technische Universität Dresden | 372 | 2020-07-09 | 2022-08-11 | |
| Reproducibility of Blood Flowmetry in Human Retina Using the Nidek Laser Speckle Flowgraphy LSFG-NAVI System LASER SPECKLE FLOWGRAPHY - Open Angle Glaucoma, Normal Tension Glaucoma | Completed | University of Zurich | 44 | 2019-07-01 | 2023-06-05 | |
| Measurement of the Effect of Gingko Biloba Extract on Ocular and Nailfold Blood-flow in NTG Gingko Baloba, Placebo - Normal Tension Glaucoma | Not applicable | Unknown | Robert Ritch, MD, LLC. | 40 | 2018-11-19 | 2020-03-17 |
| Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy Subjects Fourier Domain Doppler Optical Coherence Tomography (FDOCT), Dynamic Vessel Analyzer (DVA), Pattern Electroretinography (pERG) - Glaucoma, Open-Angle, Normal Tension Glaucoma | Not applicable | Recruiting | Medical University of Vienna | 120 | 2017-12-01 | 2025-05-23 |
| Peripapillary Blood Flow After Use of Anti-glaucoma Medications: An OCT Angiography Study Timolol Maleate, Brimonidine Tartrate - Glaucoma; Drugs, Normal Tension Glaucoma | Phase 4 | Completed | Wills Eye | 35 | 2017-07-10 | 2020-12-31 |
| Evaluation of PHP-201 Ophthalmic Solution in Patients With Normal Tension Glaucoma PHP-201 0.25% ophthalmic solution, PHP-201 0.5% ophthalmic solution, Placebo ophthalmic solution - Normal Tension Glaucoma | Phase 2 | Completed | pH Pharma | 119 | 2017-03-06 | 2018-10-26 |
| Advanced Glycation End Products as a Biomarker for Accelerated Ageing Primary Open Angle Glaucoma, Normal Tension Glaucoma | Completed | University of Plymouth | 131 | 2016-08-01 | 2019-04-16 | |
| Efficacy and Safety of COMBIGAN® in Korean Patients With Primary Open Angle Glaucoma (POAG) and Normal Tension Glaucoma (NTG) brimonidine tartrate/timolol malate Ophthalmic Solution, bimatoprost ophthalmic solution 0.01% - Glaucoma, Open-Angle, Normal Tension Glaucoma | Phase 4 | Completed | Allergan | 118 | 2016-07-05 | 2018-08-31 |
| Pressure Difference Between Brain and Eye: a Possible Cause to Normal Tension Glaucoma. Normal Tension Glaucoma | Completed | Umeå University | 17 | 2016-02-01 | 2017-05-03 |
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Low Tension Glaucoma (38) · Glaucoma, Open-Angle (16) · Glaucoma (12) · Ocular Hypertension (7) · Astigmatism (1) · Cataract (1) · Corneal Diseases (1) · Dilatation, Pathologic (1) · Exfoliation Syndrome (1) · Glaucoma, Angle-Closure (1) · Keratoconus (1) · Neoplasms (1) · Sleep Apnea, Obstructive (1)
Eye Diseases (38) · Optic Nerve Diseases (38) · Ocular Hypertension (31) · Glaucoma (26) · Apnea (1) · Dyssomnias (1) · Iris Diseases (1) · Lens Diseases (1) · Nervous System Diseases (1) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1) · Refractive Errors (1) · Respiration Disorders (1) · Respiratory Tract Diseases (1) · Sleep Apnea Syndromes (1)
Brimonidine Tartrate (4) · Tomography, Optical Coherence (3) · Timolol (2) · Bimatoprost (1) · Brimonidine Tartrate, Timolol Maleate Drug Combination (1) · Corneal Topography (1) · Latanoprost (1) · Ophthalmic Solutions (1) · Tomography (1) · Trabeculectomy (1) · Travoprost (1) · Vision, Ocular (1) · Watchful Waiting (1) · dorzolamide-timolol combination (1) · netarsudil (1)
Universitaire Ziekenhuizen KU Leuven (4) · Helsinki University Central Hospital (2) · Medical University of Vienna (2) · Technische Universität Dresden (2) · The Catholic University of Korea (2) · Alcon Research (1) · Allergan (1) · BelkinVision (1) · Intuor Technologies, Inc. (1) · Kyorin University (1) · Lithuanian University of Health Sciences (1) · Military Institute od Medicine National Research Institute (1) · Northwell Health (1) · Okuvision GmbH (1) · Rabin Medical Center (1)
United States (8) · South Korea (6) · Belgium (4) · Austria (2) · Finland (2) · Germany (2) · Japan (2) · Poland (2) · Canada (1) · China (1) · Israel (1) · Lithuania (1) · Singapore (1) · Sweden (1) · Switzerland (1)
Ingeborg Stalmans, MD, PhD (2) · Chan Kee Park, M.D., PhD. (1) · Dan Gaa'ton, MD (1) · Daniel Lee, MD (1) · Danyel Carr, MS (1) · Dorit Raz Prag (1) · Frederick Mikelberg, MD (1) · Gerhard Garhoefer, MD (1) · Ingeborg Stalmans, ND, PhD (1) · Jan Malm, MD (1) · Jingyun Wang, Ph.D (1) · Joanna Wierzbowska, MD, PhD (1) · Joy Maglambayan (1)
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