4 not yet recruiting, 3 completed, 3 recruiting, 3 unknown. 4 Not applicable, 4 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 4 | Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 4 | 4 | Not yet recruiting 3, Recruiting 1 |
Follow Noncardiac Surgery: new trials by email Literature Review of Noncardiac Surgery trials Research Report on Noncardiac Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine-esketamine Combination and Postoperative Cognitive Recovery in Older Patients Intranasal dexmedetomidine-esketamine combination, Intranasal placebo (0.9% saline) - Older Patients, Noncardiac Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 732 | 2026-11-01 | 2026-11-04 |
| Impact of Esketamine on Delayed Neurocognitive Recovery in Older Patients Esketamine 1, Esketamine 2, Esketamine 3 - Elderly, Noncardiac Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 120 | 2026-04-01 | 2026-04-14 |
| Preoperative vs Postoperative Revascularization in Coronary Heart Disease Patients Undergoing Time-Sensitive Non-Cardiac Surgery (CHRONOS-PCI) Non-cardiac surgery followed by postoperative PCI, Preoperative PCI followed by delayed non-cardiac surgery ~3 months later - Coronary Artery Disease, Noncardiac Surgery | Not applicable | Not yet recruiting | First Affiliated Hospital of Wenzhou Medical University | 140 | 2025-10-01 | 2025-09-16 |
| Transcutaneous Auricular Vagus Nerve Stimulation and Quality of Recovery After Major Noncardiac Surgery Transcutaneous auricular vagus nerve stimulation, Sham stimulation - Vagus Nerve Stimulation, Transcutaneous Electric Nerve Stimulation | Not applicable | Recruiting | Peking University First Hospital | 320 | 2025-05-13 | 2025-06-03 |
| Preemptive Analgesia Of Dexmedetomidine Reduces Per-operation Pain Preemptive Dexmedetomidine injection, Sodium Chloride 0.9% Inj - Pain Management, Noncardiac Surgery | Phase 4 | Not yet recruiting | China International Neuroscience Institution | 208 | 2025-04-03 | 2025-04-09 |
| The Choice of Vasopressor to Prevent Postoperative Acute Kidney Injury After Major Non-Cardiac Surgery Norepinephrine, Phenylephrine - Anesthesia, Surgery With General Anesthesia | Phase 4 | Recruiting | University of California, San Francisco | 18000 | 2025-04-01 | 2026-05-26 |
| The Risk of Surgical Cancellation in Adult Patients Assessed by Telephone Versus In-person for Scheduled Non-cardiac Elective Surgery. Surgical Procedures, Telemedicine | Completed | Universidad de Antioquia | 1176 | 2025-01-01 | 2026-05-05 | |
| ZYNEX Cardiac Monitor in Patients Having Noncardiac Surgery Fluid - Noncardiac Surgery | Completed | The Cleveland Clinic | 20 | 2023-03-09 | 2025-07-31 | |
| Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients Structured preoperative multidisciplinary team meeting - Interdisciplinary Communication, Postoperative Complications | Not applicable | Active not recruiting | Rijnstate Hospital | 1200 | 2022-11-01 | 2026-02-25 |
| Prediction of Vascular Events After Major Non-Cardiac Surgery : an Observational Prospective Cohort Study Perioperative cardiac biomarker measurement - Noncardiac Surgery | Recruiting | Nanfang Hospital, Southern Medical University | 20000 | 2022-07-01 | 2024-09-19 | |
| Machine Learning Model to Predict Postoperative Respiratory Failure Prediction of postoperative respiratory failure using a machine learning - Noncardiac Surgery | Completed | Seoul National University Hospital | 22250 | 2021-05-26 | 2022-09-01 | |
| Patient-Centred Outcomes and Resource Utilisation After Noncardiac Surgery-D(Eutschland) (PACORUS-D) no intervention (cohort study) - Noncardiac Surgery | Unknown | PD Dr. med. MSc Giovanna Lurati Buse | 1200 | 2021-02-01 | 2020-12-19 | |
| The Study of Anesthesia-related Risk Factors for Postoperative Death in Elderly Non-cardiac Surgery Patients in China no interventions - Postoperative Mortality, Anesthesia | Unknown | Chinese PLA General Hospital | 300000 | 2020-05-31 | 2021-06-09 | |
| The Prognostic Capabilities Of A Preoperative Six-Minute Walk Test To Independently Inform Cardiovascular Risk After Major Noncardiac Surgery Six-minute walk test to perform before surgery - Noncardiac Surgery, Postoperative Myocardial Infarction | Not applicable | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 1000 | 2016-09-07 | 2019-03-14 |
Postoperative Complications (2) · Acute Kidney Injury (1) · Agnosia (1) · Coronary Artery Disease (1) · Emergence Delirium (1)
Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Neurologic Manifestations (2) · Signs and Symptoms (2) · Arterial Occlusive Diseases (1) · Arteriosclerosis (1) · Cardiovascular Diseases (1) · Confusion (1) · Coronary Disease (1) · Delirium (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1) · Heart Diseases (1)
Sodium Chloride (2) · Cohort Studies (1) · Fluid Therapy (1) · Norepinephrine (1) · Phenylephrine (1) · Saline Solution (1)
Peking University First Hospital (3) · China International Neuroscience Institution (1) · Chinese PLA General Hospital (1) · First Affiliated Hospital of Wenzhou Medical University (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Nanfang Hospital, Southern Medical University (1) · PD Dr. med. MSc Giovanna Lurati Buse (1) · Rijnstate Hospital (1) · Seoul National University Hospital (1) · The Cleveland Clinic (1) · Universidad de Antioquia (1) · University of California, San Francisco (1)
China (7) · Canada (2) · United States (2) · Colombia (1) · Netherlands (1) · South Korea (1)
Dong-Xin Wang, MD, PhD (3) · Allison Janda, MD (1) · Amal Bessissow, MD (1) · Douglas Colquhoun, MB ChB, MSc, MPH (1) · Fabian D Casas, Professor (1) · Giovanna AL Lurati Buse, MD, MSc (1) · Jacqueline E. Vernooij, MD, MA (1) · Kurt Ruetzler, MD (1) · Matthieu Legrand, MD PhD (1) · Michael P Bokoch, MD PhD (1) · Nick J. Koning, MD PhD DESA (1) · Sachin Kheterpal, MD MBA (1)
PMID 22981128, PMID 27185698, PMID 32841990, PMID 33487917, PMID 34644199, PMID 34649158, PMID 35189166, PMID 36308990, PMID 40480911, PMID 41701325, PMID 42207991
R01DK139484 (1)