195 completed, 58 unknown, 44 recruiting, 18 not yet recruiting. 352 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 352 | Completed 195, Unknown 58, Recruiting 44, Not yet recruiting 18, Terminated 15, Active not recruiting 14, Enrolling by invitation 4, Withdrawn 3, Suspended 1 |
Follow Muscle Hypertonia: new trials by email Literature Review of Muscle Hypertonia trials Research Report on Muscle Hypertonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lateral Cord Stimulation as a New Treatment for Refractory Spastic Cerebral Palsy Lateral spinal cord surgical implant of electrodes - Cerebral Palsy, Spasticity | Not applicable | Not yet recruiting | Juan Carlos M. Andreani MD | 40 | 2027-06-01 | 2026-04-28 |
| Evaluating the Effects of the EXOPULSE Suit on Mobility, Walking Ability, and Balance in People With Multiple Sclerosis Electrostimulation suit - Multiple Sclerosis | Not applicable | Not yet recruiting | Otto Bock Healthcare Products GmbH | 100 | 2026-11-01 | 2026-10-27 |
| Addressing Spasticity and Motor Function With Epidural Spinal Cord Stimulation Epidural implant stimulation device - SCI - Spinal Cord Injury, Spasticity | Not applicable | Recruiting | Kessler Foundation | 8 | 2026-10-01 | 2026-10-22 |
| Spinal Cord Stimulation for Poststroke Spasticity Active spinal cord stimulation, Sham spinal cord stimulation - Spasticity Post Stroke | Not applicable | Recruiting | Beijing Pins Medical Co., Ltd | 92 | 2026-09-09 | 2026-09-21 |
| Intermittent Theta-Burst Stimulation for Lower-Limb Spasticity and Pain in Multiple Sclerosis Active Intermittent Theta-Burst Stimulation (iTBS), Sham Intermittent Theta-Burst Stimulation - Multiple Sclerosis, Muscle Spasticity | Not applicable | Not yet recruiting | Comenius University | 40 | 2026-08-10 | 2026-08-26 |
| Co-contraction and Corticoreticular Excitability in Spinal Cord Injury Corticoreticular excitability and co-contraction measurement - Spinal Cord Injury, Spasticity | Not applicable | Enrolling by invitation | Taipei Veterans General Hospital, Taiwan | 20 | 2026-07-27 | 2026-10-14 |
| Extracorporeal Shock Wave Therapy in Botulinum Toxin-Treated Patients With Post-Stroke Ankle Plantar Flexor Spasticity Radial Extracorporeal Shock Wave Therapy (rESWT), Conventional Physical Therapy and Rehabilitation - Stroke, Post-stroke Spasticity of the Lower Limb | Not applicable | Not yet recruiting | Pamukkale University | 32 | 2026-07-20 | 2026-07-10 |
| Dorsal Root Electrical Stimulation in Children With Cerebral Palsy Constant Current Stimulator, Cadwell Guardian System - Cerebral Palsy (CP), Cerebral Palsy | Not applicable | Recruiting | Martin Piazza | 15 | 2026-07-16 | 2026-08-11 |
| Selective Dorsal Rhizotomy as a Cost Effective and Safe Procedure as a Alternative to Intrathecal Baclofen Pump in Patients With Post Traumatic Spasticity Selective dorsal rhizotomy with neuromonitoring - Post Traumatic Induced Spasticity | Not applicable | Not yet recruiting | Assiut University | 32 | 2026-06-01 | 2026-05-13 |
| Constraint-induced Movement Therapy Combined With Functional Electrical Stimulation in Children With Cerebral Palsy Constraint-Induced Movement Therapy Combined with Functional Electrical Stimulation, Constraint-Induced Movement Therapy - Cerebral Palsy (CP) | Not applicable | Completed | Montiha Azeem | 46 | 2026-05-18 | 2026-07-06 |
| Effects of Functional Electrical Stimulation on Spasticity, Quadriceps Muscle Strength and Functional Mobility in Individuals With Paraplegia Conventional Neurorehabilitation, Functional Electrical Stimulation (FES) of Quadriceps Muscle, Sham FES group: Conventional neurorehabilitation + sham/placebo FES - Spinal Cord Injury, Paraplegia | Not applicable | Withdrawn | Istanbul Medipol University Hospital | 2026-05-10 | 2026-10-28 | |
| Trial to Test the Effectiveness of Vibrotactile Stimulation for Lower Limb Spasticity Vibrotactile Stimulation (Static Use), Vibrotactile Stimulation (Dynamic Use), Vibrotactile Stimulation (Neurophysiological Mechanism) - Lower Limb Spasticity | Not applicable | Recruiting | Weill Medical College of Cornell University | 25 | 2026-04-30 | 2026-06-17 |
| tDCS and Bi-manual Training in Cerebral Palsy Anodal tDCS, Sham tDCS - Cerebral Palsy (CP), Unilateral Cerebral Palsy | Not applicable | Not yet recruiting | Riphah International University | 15 | 2026-04-30 | 2026-05-07 |
| Effect of Extracorporeal Shock Wave Therapy on Spasticity and Mobility in Stroke Patients Extracorporeal Shock Wave Therapy (ESWT), Sham Extracorporeal Shock Wave Therapy - Stroke, Post-Stroke Spasticity | Not applicable | Completed | Istanbul Medipol University Hospital | 85 | 2026-04-10 | 2026-10-28 |
| Spinal Cord Stimulation for Children With Cerebral Palsy Transcutaneous Spinal Cord Stimulation (tSCS) - Cerebral Palsy, Spasticity | Not applicable | Recruiting | Martin Piazza | 30 | 2026-03-30 | 2026-04-07 |
| Spasticity in SCI Following Acute Intermittent Hypoxia Acute Intermittent Hypoxia (AIH) - Spinal Cord Injuries (SCI) | Not applicable | Recruiting | Zev Rymer | 10 | 2026-03-17 | 2026-05-13 |
| At Home Use of Stimulation Suits for Managing MS Symptoms electro-stimulation suit, Usual Care - Multiple Sclerosis, MS (Multiple Sclerosis) | Not applicable | Recruiting | Daphne Kos | 70 | 2026-03-16 | 2026-10-08 |
| Acute Effects of Wearable Electrical Stimulation in Stroke EXOPULSE Mollii Suit, EXOPULSE Mollii Suit with Sham Stimulation - Stroke | Not applicable | Not yet recruiting | Hacettepe University | 26 | 2026-03-15 | 2026-03-12 |
| Vibrotactile Coordinated Reset for Spasticity After Spinal Cord Injury Vibrotactile Coordinated Reset - Spasticity, Muscle, Spinal Cord Injuries | Not applicable | Not yet recruiting | Stanford University | 30 | 2026-03-15 | 2025-05-15 |
| Effectiveness of TMS on Spasticity and Balance for Patients With MS rTMS, sham rTMS - Multiple Sclerosis | Not applicable | Recruiting | Ankara Etlik City Hospital | 24 | 2026-03-01 | 2026-04-03 |
Showing 20 of 352. Sign in to see all of them.
Muscle Spasticity (321) · Stroke (129) · Cerebral Palsy (83) · Spinal Cord Injuries (40) · Hemiplegia (29) · Multiple Sclerosis (28) · Muscle Rigidity (16) · Pain (15) · Paresis (15) · Brain Injuries, Traumatic (8) · Motor Activity (8) · Gait Disorders, Neurologic (7) · Ischemic Stroke (7) · Parkinson Disease (7)
Pathological Conditions, Signs and Symptoms (352) · Signs and Symptoms (352) · Neuromuscular Manifestations (351) · Nervous System Diseases (349) · Neurologic Manifestations (348) · Muscular Diseases (339) · Musculoskeletal Diseases (339) · Central Nervous System Diseases (261) · Brain Diseases (227) · Cardiovascular Diseases (132) · Cerebrovascular Disorders (131) · Vascular Diseases (131) · Brain Damage, Chronic (83) · Wounds and Injuries (48)
Dry Needling (15) · Extracorporeal Shockwave Therapy (13) · Botulinum Toxins, Type A (10) · Physical Therapy Modalities (8) · Control Groups (6) · Muscle Stretching Exercises (6) · Rehabilitation (6) · Transcranial Direct Current Stimulation (6) · Transcranial Magnetic Stimulation (5) · Transcutaneous Electric Nerve Stimulation (5) · Constraint Induced Movement Therapy (4) · Exercise (3) · Exercise Therapy (3) · Low-Level Light Therapy (3) · Therapeutics (3)
Riphah International University (19) · Chang Gung Memorial Hospital (7) · Hacettepe University (5) · Kessler Foundation (5) · Shirley Ryan AbilityLab (5) · Assistance Publique - Hôpitaux de Paris (4) · BTL Industries Ltd. (4) · Chang Gung University (4) · Foundation University Islamabad (4) · Institut De La Colonne Vertebrale Et Des Neurosciences (4) · Istanbul Physical Medicine Rehabilitation Training and Research Hospital (4) · Medical University of South Carolina (4) · Pamukkale University (4) · Shepherd Center, Atlanta GA (4) · University of Lahore (4)
United States (67) · Turkey (Türkiye) (48) · Pakistan (34) · France (24) · Spain (23) · Taiwan (17) · Egypt (13) · Italy (11) · Belgium (10) · Brazil (10) · United Kingdom (7) · Saudi Arabia (6) · Canada (5) · Sweden (5) · China (4)
Mirza Obaid Baig, MSPT (3) · Aiko K Thompson, PhD (2) · Hung Jen-Wen (2) · Jen-Wen Hung (2) · Kjell-Morten Myhr, MD, PhD (2) · Martin G Piazza, MD (2) · Mirza Obaid Baig, MSPT(NMR) (2) · Peter Vestergaard Rasmussen, MD, PhD (2) · Sara Haghighi Mobarhan Smith, MD, PhD (2) · Shu-mei Yang, MD (2) · William Z Rymer, MD, PhD (2)
PMID 27149465, PMID 34721255, PMID 7192811, PMID 12088304, PMID 12593613, PMID 1392142, PMID 14179895, PMID 14506719, PMID 14515935, PMID 14970972, PMID 16780624, PMID 16914068, PMID 17084128, PMID 17209981, PMID 17370477, PMID 17979861, PMID 18292215, PMID 19011522, PMID 19083678, PMID 19480872, PMID 19597267, PMID 19834018, PMID 20358168, PMID 21486759, PMID 21530725, PMID 21729249, PMID 23064478, PMID 23090951, PMID 23319485, PMID 23422453, PMID 23652265, PMID 23885710, PMID 23949081, PMID 24020026, PMID 24269277, PMID 24291625, PMID 25180530, PMID 25199575, PMID 25461434, PMID 25475608, PMID 25530960, PMID 25547767, PMID 25575288, PMID 26032205, PMID 26079868, PMID 26223831, PMID 26271048, PMID 2638119, PMID 26392035, PMID 26515205
2016 (1), 2018 (1), 2025 (1), I01RX002507 (1), I21RX004652 (1), K23NS044997 (1), P20GM109040 (1), R01HD075813 (1), R01HD112563 (1), R01NS114279 (1), R15HD071397 (1), R21NS130367 (1), R61HL151952 (1), U44NS104138 (1), U44NS114420 (1)