56 completed, 9 unknown, 7 active not recruiting, 7 recruiting. 71 Not applicable, 2 Phase 1, 1 Phase 2.
Follow Multiple Chronic Conditions: new trials by email Literature Review of Multiple Chronic Conditions trials Research Report on Multiple Chronic Conditions
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Personalized Routine and Habit Integration to Support Medication Management PRISM Arm, Enhanced Usual Care Arm - Medication Adherence | Not applicable | Not yet recruiting | Brigham and Women's Hospital | 100 | 2027-02-01 | 2026-11-03 |
| "My Health Priorities" Program for Rural and Underserved Older Adults With Multiple Chronic Conditions (MyHP-South) MyHP-South Program - Multiple Chronic Conditions, Shared Decision-making | Not applicable | Not yet recruiting | University of Alabama at Birmingham | 44 | 2027-01-01 | 2026-11-09 |
| Integrated Digital Health System With Electronic Decision Support, Assisted Telemedicine and MHeAlth-Supported Self-ManaGement to Improve Health-Related Quality of Life Among Adults With Multiple Long-Term Conditions in Primary Health Centres in India and Nepal: A Cluster Randomised Controlled Trial Electronic Decision Support System (EDSS), Assisted Telemedicine, Patient-facing mobile application and care coordination by Care Mitras - Chronic Conditions, Multiple, Diseases of the Circulatory System | Not applicable | Active not recruiting | Centre for Chronic Disease Control, India | 3600 | 2026-05-18 | 2026-11-10 |
| Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities Cardiovascular, Comorbidity | Recruiting | University of Alabama at Birmingham | 29 | 2026-05-01 | 2026-08-06 | |
| Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness Acupuncture - Persian Gulf Syndrome, Gulf War Syndrome | Not applicable | Recruiting | University of Utah | 200 | 2026-02-03 | 2026-04-03 |
| Developing an Innovative Decision Support Tool for Pediatric Neuromuscular Scoliosis Decision support tool - Children With Medical Complexity (CMC), Multiple Chronic Conditions | Not applicable | Recruiting | University of Utah | 110 | 2025-10-21 | 2026-08-10 |
| Health Literacy Levels of Patients Living With Type 2 Diabetes and Multi-disease and Their Families Using HLQTM Health Literacy | Completed | University of Southern Denmark | 4611 | 2025-10-01 | 2026-05-19 | |
| A Web-Based Tool to Help People With Health Conditions Make Contraceptive Decisions My Health, My Choice Web-Based Contraceptive Decision Tool, Usual Contraceptive Care - Contraceptive Usage, Contraceptive Behavior | Not applicable | Enrolling by invitation | University of Michigan | 795 | 2025-09-15 | 2026-10-06 |
| Addressing Social Needs to Improve Health in Adults With Multiple Chronic Conditions Telephonic Outreach, Virtual Outreach - Multiple Chronic Conditions, Social Needs | Not applicable | Recruiting | Kaiser Permanente | 800 | 2025-09-01 | 2026-06-05 |
| AI-Augmented Motivational Interviewing Training for Primary Care Basic AI (artificial intelligence)-Augmented Motivational Interviewing Training, Plus AI (artificial intelligence)-Augmented Motivational Interviewing Training - Multiple Chronic Conditions, Patient Engagement | Not applicable | Not yet recruiting | Wright State University | 150 | 2025-07-01 | 2024-09-19 |
| Personalized Digital Remote Monitoring for Elderly Patients Remote Patient Monitoring system - Elderly Patients, Polypathology | Not applicable | Not yet recruiting | EPOCA U&I | 700 | 2025-06-15 | 2025-02-25 |
| Psychometric Validation of the Flemish Version of the Transition Readiness Assessment Questionnaire (TRAQ 6.0) in Young People With Chronic Conditions Chronic Conditions, Multiple | Completed | Universiteit Antwerpen | 128 | 2025-03-01 | 2026-10-01 | |
| The Cohort Construction Project of Peking University Third Hospital observational study - Multiple Chronic Conditions (Unspecified), Large-scale Health Examination Cohort | Recruiting | Peking University Third Hospital | 100000 | 2025-02-21 | 2026-08-12 | |
| Evaluating Covered California's Grocery Support Program Grocery Support Monthly Program, Grocery Support One-Time Payment - Chronic Conditions, Multiple, Chronic Conditions | Not applicable | Active not recruiting | University of California, San Francisco | 6975 | 2025-02-01 | 2026-07-14 |
| Impact of Goal-Directed Care Interventions Goal-Oriented Care Model, standard health education - Multiple Chronic Diseases | Not applicable | Not yet recruiting | Chang Gung Memorial Hospital | 200 | 2025-01-25 | 2025-02-05 |
| Digitally Supported Person-centered Care Systems 03 - Summaries of and clinical notes from several providers, 01 - Clinical notes from one provider, 02 - Access to notes from primary and secondary care - Multiple Chronic Conditions | Not applicable | Completed | University Hospital of North Norway | 93 | 2024-06-18 | 2026-09-28 |
| A Physiotherapy-led Disease-agnostic Telerehabilitation Programme for People With Chronic Health Conditions TECC (Telerehabilitation and Exercise for Chronic Conditions) - Chronic Conditions, Multiple | Not applicable | Completed | University of Limerick | 30 | 2024-04-16 | 2024-12-12 |
| Optimizing Telehealth-delivery of a Weight Loss Intervention in Older Adults Prescriptive, Behavioral - Obesity, Multiple Chronic Conditions | Not applicable | Recruiting | University of North Carolina, Chapel Hill | 180 | 2024-04-16 | 2026-02-06 |
| The Impact of Long COVID on People Living With Pre-existing LTC Long COVID, Multiple Chronic Conditions | Unknown | University of Leicester | 20 | 2024-02-01 | 2024-02-14 | |
| An Accessible and Inclusive Artificial Intelligence Assisted Chronic Disease Self-Management Telehealth Platform Scheduled Coaching + Gamified Rewards, Scheduled Coaching Calls + Independent Rewards, No Scheduled Coaching Calls + Gamified Rewards - Disability Physical, Chronic Condition | Not applicable | Completed | University of Alabama at Birmingham | 212 | 2024-02-01 | 2025-12-18 |
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Chronic Disease (18) · Diabetes Mellitus (9) · Hypertension (7) · Depression (4) · Frailty (3) · Motor Activity (3) · Psychological Well-Being (3) · Dementia (2) · Diabetes Mellitus, Type 2 (2) · Health Behavior (2) · Leukemia, Lymphocytic, Chronic, B-Cell (2) · Leukemia, Myelogenous, Chronic, BCR-ABL Positive (2) · Obesity (2) · Patient Participation (2)
Disease Attributes (89) · Pathologic Processes (89) · Pathological Conditions, Signs and Symptoms (89) · Chronic Disease (71) · Behavior (14) · Nutritional and Metabolic Diseases (14) · Metabolic Diseases (12) · Endocrine System Diseases (11) · Glucose Metabolism Disorders (10) · Cardiovascular Diseases (9) · Vascular Diseases (9) · Nervous System Diseases (7) · Signs and Symptoms (6) · Behavioral Symptoms (5) · Respiratory Tract Diseases (5)
Exercise (3) · Occupational Therapy (2) · Patient Reported Outcome Measures (2) · Acclimatization (1) · Acupuncture Therapy (1) · Alkalies (1) · Directive Counseling (1) · Educational Status (1) · Narrative Therapy (1) · Observation (1) · Pharmaceutical Preparations (1) · Secondary Care (1) · Telemedicine (1) · Telerehabilitation (1) · Vitamin D (1)
University of Alabama at Birmingham (5) · University of Utah (4) · McMaster University (3) · Parker Research Institute (3) · University of North Carolina, Chapel Hill (3) · VA Office of Research and Development (3) · Brigham and Women's Hospital (2) · Innovation Research & Training (2) · Radboud University Medical Center (2) · University Hospitals Cleveland Medical Center (2) · University of Wisconsin, Madison (2) · Yale University (2) · Centre for Chronic Disease Control, India (1) · Chang Gung Memorial Hospital (1) · Children's Hospital Los Angeles (1)
United States (53) · Canada (7) · Denmark (4) · Spain (3) · Belgium (2) · Netherlands (2) · Norway (2) · United Kingdom (2) · Brazil (1) · China (1) · Colombia (1) · Finland (1) · India (1) · Ireland (1) · Israel (1)
Alison Parker, PhD (2) · Maureen Markle-Reid, RN, PhD (2) · Aanand D Naik, MD (1) · Alex H Krist, MD MPH (1) · Alexandra Papaioannou, MD, MSc, FRCP(c), FACP (1) · Anuj Dalal, MD (1) · Ardeshir Hashmi, MD (1) · Ariel Green, MD, MPH, PhD (1) · Ashley M Weber, PhD, RN, RNC-NIC (1) · Brodie Sakakibara, PhD (1) · Carol Rovira (1) · Caroline Fichtenberg, PhD (1) · Claudia Borzutzky, MD (1)
PMID 31589281, PMID 20053272, PMID 20511102, PMID 21689904, PMID 21838834, PMID 22145124, PMID 22376048, PMID 23250366, PMID 25114561, PMID 25324330, PMID 25469987, PMID 25767307, PMID 26908524, PMID 27537241, PMID 27717532, PMID 27965180, PMID 28339923, PMID 28510645, PMID 28705187, PMID 28817334, PMID 28823545, PMID 29433501, PMID 31908421, PMID 32088427, PMID 32110005, PMID 32527322, PMID 32749995, PMID 33034566, PMID 33583002, PMID 34116727, PMID 34836902, PMID 34881189, PMID 35120457, PMID 35132555, PMID 35140146, PMID 35274737, PMID 35751871, PMID 35781226, PMID 35899784, PMID 35917127, PMID 35974460, PMID 36125214, PMID 36254368, PMID 36451059, PMID 36560290, PMID 36566620, PMID 37019487, PMID 37054983, PMID 37090953, PMID 37115620
2016 (1), K23AG054742 (1), K23AR079778 (1), K23NR019081 (1), K76AG059934 (1), P30AG064199 (1), P30NR018093 (1), R01AG062686 (1), R01AG077163 (1), R01HD110570 (1), R01NR017614 (1), R15NR017302 (1), R33HL151870 (1), R61HL151870 (1), U54AG093230 (1)