21 completed, 10 recruiting, 5 unknown, 3 not yet recruiting. 30 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 30 | Completed 14, Recruiting 7, Unknown 4, Not yet recruiting 2, Active not recruiting 1, Terminated 1, Withdrawn 1 |
Follow Lower Limb Amputation: new trials by email Literature Review of Lower Limb Amputation trials Research Report on Lower Limb Amputation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Footwear on Gait in Unilateral Transtibial Amputees Own Footwear, Oxford Shoe, Walking/Running Shoe - Transtibial Amputation, Lower Limb Amputation | Not applicable | Recruiting | University of Salford | 15 | 2026-11-03 | 2026-10-23 |
| Acute Post-Amputation Pain Management After Combat-Related Lower Limb Injury Continuous Peripheral Nerve Blocks, Peripheral Nerve Cryoablation, Standard multimodal analgesia - Postamputation Pain, Lower Limb Amputation | Not applicable | Not yet recruiting | Kharkiv National Medical University | 36 | 2026-10-10 | 2026-10-07 |
| Exploratory Functional Assessment After Lower Limb Amputation: Locomotion, Balance, Energy Performance and Strategies for Adapting to Orthopaedic Devices Walk tests, Functional testing, Balance analysis - Lower Limb Amputation | Not applicable | Recruiting | Centre Hospitalier Universitaire Dijon | 100 | 2026-09-18 | 2026-09-28 |
| Dual-Task Balance Training in Traumatic Lower-Limb Prosthesis Users Dual-Task Balance Training, Standard Rehabilitation - Lower Limb Amputation, Prosthesis Users | Not applicable | Recruiting | Al-Azhar University - Gaza | 63 | 2026-07-08 | 2026-07-23 |
| Development of a Performance Model for Amputee Football Players Gince Intelligence Game-Based Exercise Program, Routine Training Group - Cognitive Games, Sports Performance | Not applicable | Recruiting | Tarsus University | 20 | 2026-06-26 | 2026-09-25 |
| Psychometric Evaluation of the Multidimensional Scale of Perceived Social Support in Lower Extremity Amputation No Intervention: Observational Cohort - Lower Limb Amputation | Not yet recruiting | Hacettepe University | 55 | 2026-01-30 | 2026-01-30 | |
| Muscle Strength Training in Lower Limb Amputee Patients Muscle strengh training, Resistence training - Lower Limb Amputation | Not applicable | Not yet recruiting | University of Gran Rosario | 18 | 2025-11-30 | 2025-12-03 |
| The Role of Visual Attention and Environmental Complexity in Real-world Mobility for People With Lower Limb Amputation Comprehensive assessment of walking patterns and functional mobility, Comprehensive assessment of eye movements during walking, Questionnaire Assessments completed - Lower Limb Amputation | Recruiting | Virginia Commonwealth University | 30 | 2025-10-25 | 2026-09-21 | |
| Effect of Balance Exercises on Performance in Amputee Football Players Balance and Trunk Stabilization Exercise Program - Lower Limb Amputation, Balance Impairment | Not applicable | Completed | Istanbul Rumeli University | 20 | 2025-10-02 | 2026-07-20 |
| Intrathecal Dexmedetomidine and Acute Neuropathic Pain After Lower Limb Amputation Hyperbaric Bupivacaine plus Saline, Hyperbaric Bupivacaine plus Dexmedetomidine - Phantom Limb Pain, Neuropathic Pain | Not applicable | Completed | Universidad Juárez Autónoma de Tabasco | 30 | 2025-09-30 | 2026-10-21 |
| Identification of Limiting Factors in the Locomotor Activity of Individuals With Lower Limb Amputation: None, pure observationnal study - Lower Limb Amputation | Recruiting | Centre Hospitalier Universitaire de Nīmes | 200 | 2025-03-15 | 2026-06-24 | |
| Uses of Phantom Sensations Induced by Global and Local Modifications of the Prosthetic Socket as Somatosensory Feedback During Walking in Lower Limb Amputees Gait analysis, Mapping of referred sensations., Exploration of the areas of the brain activated during referred sensations - Lower Limb Amputation | Not applicable | Recruiting | Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est | 228 | 2024-09-16 | 2025-09-25 |
| Effect of PNF-Based Upper Extremity Strengthening With Core Stabilization on Fitness in Amputee Football Players Training, Control Group - Amputation, Lower Limb Amputation | Not applicable | Active not recruiting | Uskudar University | 14 | 2024-09-01 | 2026-04-01 |
| Epidural Oxycodone for Pain Management for Lower Limb Amputation Oxycodone, Bupivacaine - Epidural, Oxycodone | Not applicable | Unknown | Kafrelsheikh University | 40 | 2024-02-24 | 2024-02-28 |
| Pilot Study on the Evaluation of the Functionality, Safety and Reliability of New Tripping Devices for Lower Limbs. prosthetic group performs the entire protocol with their own prosthesis, Experimental Group - Lower Limb Amputation, Slip Perturbations | Completed | Fondazione Don Carlo Gnocchi ETS | 8 | 2024-02-06 | 2026-03-27 | |
| Identification of Priority Clinical Variables in Rehabilitation of Lower Extremity Amputation Hierarchical Cluster Analysis - Lower Limb Amputation | Completed | Cigdem Cinar | 70 | 2023-12-23 | 2025-03-31 | |
| Operant Conditioning of Sensory Brain Responses to Reduce Phantom Limb Pain in People With Limb Amputation Operant Conditioning with Peripheral Stimulation, Control Group with Peripheral Stimulation Only - Phantom Limb Pain After Amputation, Lower Limb Amputation | Not applicable | Completed | VA Office of Research and Development | 20 | 2023-07-01 | 2026-01-16 |
| Clinical and Psychological Adjustment of Patients With LLA: a Multidisciplinary Rehabilitative Intervention Project Multidisciplinary Conventional and Technology-based Rehabilitation, Multidisciplinary Conventional Rehabilitation - Lower Limb Amputation, Prosthesis User | Not applicable | Recruiting | Istituti Clinici Scientifici Maugeri SpA | 70 | 2023-06-01 | 2026-02-23 |
| Perineural Methylene Blue Infusion in Lower Limb Amputation Surgery Bupivacaine methylene blue, bupivacaine saline - Perineural, Methylene Blue | Not applicable | Recruiting | Tanta University | 72 | 2023-05-01 | 2026-07-06 |
| Study of Lower-limb Phantom Pain Syndrome Using Peripheral Nerve and Spinal Cord Stimulation Implantation of PNS electrodes during surgery, mapping to select sites with the best effect and daily modulation., SCS electrode implantation at surgery, mapping to select sites with the best effect and pain modulation, Change according to the scale of the PainDetect questionnaire - Phantom Limb Pain, Phantom Pain | Not applicable | Unknown | Artur Biktimirov | 10 | 2022-11-17 | 2023-04-11 |
Showing 20 of 42. Sign in to see all of them.
Phantom Limb (3) · Neuralgia (2) · Amputation, Traumatic (1) · Bursitis (1) · Chronic Pain (1) · Fractures, Bone (1) · Mobility Limitation (1) · Pain (1) · Peroneal Neuropathies (1) · Pneumonia (1) · Psychological Well-Being (1) · Stroke (1) · Tendinopathy (1)
Nervous System Diseases (6) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Pain (4) · Neurobehavioral Manifestations (3) · Neuromuscular Diseases (3) · Pain, Postoperative (3) · Pathologic Processes (3) · Perceptual Disorders (3) · Peripheral Nervous System Diseases (3) · Postoperative Complications (3) · Wounds and Injuries (2) · Behavior (1) · Brain Diseases (1)
Control Groups (2) · Surveys and Questionnaires (2) · Artificial Limbs (1) · Bupivacaine (1) · Capsaicin (1) · Dexmedetomidine (1) · Gait Analysis (1) · Orthotic Devices (1) · Oxycodone (1) · Sodium Chloride (1) · Telerehabilitation (1) · Transcutaneous Electric Nerve Stimulation (1) · Walking (1)
Centre Hospitalier Universitaire Dijon (3) · Fondazione Don Carlo Gnocchi ETS (2) · Ohio Willow Wood (2) · Queen Margaret University (2) · Union de Gestion des Etablissements des Caisses d'Assurance Maladie - Nord Est (2) · University Rehabilitation Institute, Republic of Slovenia (2) · University of British Columbia (2) · Al-Azhar University - Gaza (1) · Artur Biktimirov (1) · Centre Hospitalier Universitaire de Nīmes (1) · Cigdem Cinar (1) · FondationbHopale (1) · Hacettepe University (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · Indiana University (1)
United States (8) · France (7) · United Kingdom (5) · Italy (4) · Turkey (Türkiye) (4) · Canada (2) · Egypt (2) · Slovenia (2) · Mexico (1) · Netherlands (1) · Pakistan (1) · Palestinian Territories (1) · Russia (1) · Singapore (1) · Ukraine (1)
Gayle Gordillo, MD (2) · Judy Scopes, MPhil (2) · Marietta van der Linden, MSc, PhD (2) · Amelie A Touillet (1) · Antonia Dr Pierobon (1) · Arshad Nawaz Malik, PhD (1) · Chandan Sen, PhD (1) · Cleveland T Barnett, Ph.D (1) · Emma L Aitken, MBChB (1) · Gabriel M Kim, M.D. (1) · Helena Burger, MD, PhD (1)
PMID 37276273, PMID 11494181, PMID 21859635, PMID 25533902, PMID 27485674, PMID 28355039, PMID 32037876, PMID 34706654, PMID 34841917, PMID 35079822, PMID 41270063
I21RX004410 (1)