15 unknown. 15 Phase 1, 12 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 15 | Unknown 15 |
| Phase 2 | 12 | Unknown 12 |
Follow Liver Failure: new trials by email Literature Review of Liver Failure trials Research Report on Liver Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hepatocyte Microbeads for Acute Liver Failure HMB002 - Acute Liver Failure | Phase 1 / Phase 2 | Unknown | King's College Hospital NHS Trust | 17 | 2022-09-01 | 2022-08-08 |
| Use of Direct Peritoneal Resuscitation in High-risk Liver Transplant Recipients Direct Peritoneal Resuscitation - End Stage Liver DIsease, Obesity | Phase 1 | Unknown | University of Colorado, Denver | 15 | 2022-02-01 | 2023-06-08 |
| Safety and Efficacy of Mesenchymal Stem Cell Transplantation for Acute-on-Chronic Liver Failure Mesenchymal Stem Cell - Liver Failure, Acute on Chronic | Phase 1 / Phase 2 | Unknown | Tianjin Weikai Bioeng., Ltd. | 45 | 2019-10-01 | 2019-03-20 |
| Using Ex-vivo Normothermic Machine Perfusion With the Organox Metra™ Device to Store Human Livers for Transplantation OrganOx Metra - End-stage Liver Disease | Phase 1 | Unknown | University Health Network, Toronto | 40 | 2015-07-01 | 2022-04-12 |
| Pneumatic Reversible Portal Vein Diameter Modulation After Major Hepatectomy MID-AVR - Liver Failure, Major Hepatectomy | Phase 1 / Phase 2 | Unknown | Assistance Publique - Hôpitaux de Paris | 12 | 2015-04-18 | 2019-04-16 |
| Safety and Efficacy of Diverse Mesenchymal Stem Cells Transplantation for Liver Failure Conventional plus BM-MSC treatment, Conventional plus UC-MSC treatment, Conventional treatment - Liver Failure | Phase 1 / Phase 2 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 210 | 2013-07-01 | 2013-07-08 |
| Umbilical Cord Mesenchymal Stem Cells Transplantation Combined With Plasma Exchange for Patients With Liver Failure Conventional plus UC-MSC treatment, Conventional plus PE treatment, Conventional plus UC-MSC and PE therapy - Liver Failure | Phase 1 / Phase 2 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 120 | 2012-11-01 | 2013-02-28 |
| Mobilization of Stem Cells With G-CSF and Mozobil in Patients With End Stage Liver Disease Mobilization with G-CSF and Mozobil - End Stage Liver DIsease | Phase 1 | Unknown | Proteonomix, Inc. | 15 | 2012-10-01 | 2013-01-24 |
| Safety and Efficacy of Human Bone Marrow Stem Cells for Treatment of HBV-related Liver Cirrhosis BMSC transplantation, conventional treatment & antivrial treatment - Liver Cirrhosis, End Stage Liver Disease | Phase 1 / Phase 2 | Unknown | Air Force Military Medical University, China | 240 | 2012-09-01 | 2012-11-12 |
| Safety and Efficacy of Human Autologous Peripheral Blood Stem Cells for Treatment of HBV-related Liver Cirrhosis PBSC transplantation, conventional treatment - Liver Cirrhosis, End Stage Liver Disease | Phase 1 / Phase 2 | Unknown | Air Force Military Medical University, China | 240 | 2012-09-01 | 2012-11-20 |
| Safety and Efficacy of Human Umbilical Cord Derived Mesenchymal Stem Cells for Treatment of HBV-related Liver Cirrhosis UC-MSC transplantation, conventional treatment - Liver Cirrhosis, End Stage Liver Disease | Phase 1 / Phase 2 | Unknown | Air Force Military Medical University, China | 240 | 2012-09-01 | 2012-11-20 |
| Efficacy of Sildenafil in the Improvement of Cognition and Quality of Life in Patients With Cirrhosis of Liver. A Proof of Concept Study. Sildenafil. - Hepatic Encephalopathy. | Phase 1 / Phase 2 | Unknown | Post Graduate Institute of Medical Education and Research, Chandigarh | 50 | 2012-07-01 | 2014-01-07 |
| Intra-hepatic Artery Bone Marrow Derived Stem Cells Infusion for the Treatment of Advanced Liver Cirrhosis Stem cell transplant - End Stage Liver Disease | Phase 1 / Phase 2 | Unknown | King Saud University | 50 | 2011-09-01 | 2011-08-09 |
| Safety and Efficacy of Human Mesenchymal Stem Cells for Treatment of Liver Failure Conventional plus MSC treatment, Conventional plus pacebo treatment - Liver Failure, Mesenchymal Stem Cells | Phase 1 / Phase 2 | Unknown | Beijing 302 Hospital | 70 | 2009-03-01 | 2013-05-31 |
| Phase I/II Study of Recombinant Human Hepatocyte Growth Factor in Fulminant Hepatic Failure Recombinant human hepatocyte growth factor - Liver Failure, Acute | Phase 1 / Phase 2 | Unknown | Kyoto University, Graduate School of Medicine | 16 | 2005-09-01 | 2005-09-26 |
End Stage Liver Disease (7) · Liver Cirrhosis (3) · Liver Failure, Acute (2) · Acute Kidney Injury (1) · Acute-On-Chronic Liver Failure (1) · Hepatic Encephalopathy (1) · Hepatitis B (1) · Obesity (1) · Renal Insufficiency (1)
Digestive System Diseases (15) · Hepatic Insufficiency (15) · Liver Diseases (15) · Pathological Conditions, Signs and Symptoms (4) · Fibrosis (3) · Pathologic Processes (3) · Nutritional and Metabolic Diseases (2) · Blood-Borne Infections (1) · Body Weight (1) · Brain Diseases (1) · Brain Diseases, Metabolic (1) · Central Nervous System Diseases (1) · Communicable Diseases (1) · DNA Virus Infections (1)
Congresses as Topic (3) · Antiviral Agents (1) · Filgrastim (1) · Granulocyte Colony-Stimulating Factor (1) · Peripheral Blood Stem Cell Transplantation (1) · Sildenafil Citrate (1) · Stem Cell Transplantation (1) · plerixafor (1)
Air Force Military Medical University, China (3) · Third Affiliated Hospital, Sun Yat-Sen University (2) · Assistance Publique - Hôpitaux de Paris (1) · Beijing 302 Hospital (1) · King Saud University (1) · King's College Hospital NHS Trust (1) · Kyoto University, Graduate School of Medicine (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Proteonomix, Inc. (1) · Tianjin Weikai Bioeng., Ltd. (1) · University Health Network, Toronto (1) · University of Colorado, Denver (1)
China (7) · United States (2) · Canada (1) · France (1) · India (1) · Japan (1) · Saudi Arabia (1)
Daiming Fan (3) · Anil Dhawan, Professor (1) · Baburao Koneru, MD (1) · David R Grant, MD (1) · Fu-Sheng Wang, Professor (1) · Hunter B Moore, M.D., P.hD. (1) · Qi Zhang, Doctor (1) · Radha K Dhiman, MD, DM, FACG (1) · Tsutomu Chiba, M.D. (1) · Zhi-Liang Gao, Doctor (1)
PMID 17903050, PMID 19455046, PMID 30863450
2019 (1)