27 completed. 27 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 27 | Completed 27 |
Follow Lethargy: new trials by email Literature Review of Lethargy trials Research Report on Lethargy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cognitive Stimulation Therapy and Olderly People With Mild Cognitive Impairment Cognitive Stimulation Therapy - Mild Cognitive Impairment | Not applicable | Completed | Ejdane Coskun | 60 | 2023-10-30 | 2024-01-23 |
| Cognitive Stimulation Therapy Cognitive Stimulation Therapy - Alzheimer Disease 10, Dementia | Not applicable | Completed | Hasan Kalyoncu University | 56 | 2023-05-01 | 2024-03-15 |
| Home-based Transcranial Direct Current Stimulation (tDCS) for Behavioral Symptoms in Alzheimer's Disease and Related Dementias (ADRD) active tDCS - Alzheimer Disease | Not applicable | Completed | The University of Texas Health Science Center, Houston | 3 | 2023-04-17 | 2025-10-10 |
| Lifestyle Intervention for Improving Insulin Resistance and Concern for Health Diet without soy, Diet with soy - Insulin Sensitivity, Apathy | Not applicable | Completed | Pennington Biomedical Research Center | 40 | 2023-02-13 | 2026-09-09 |
| Use of Socially Assistive Robots for Long Term Care Older Adults With Cognitive Impairment and Apathy Socially Assistive Robot Activity - Alzheimer Disease | Not applicable | Completed | Vanderbilt University | 142 | 2023-02-07 | 2026-10-23 |
| Virtual Reality Intervention for the Reduction of Behavioral and Psychological Symptoms of Dementia LUMEEN Virtual Reality sessions, Control/non-digital stimulation sessions - Dementia, Alzheimer's Disease | Not applicable | Completed | Hospices Civils de Lyon | 56 | 2022-12-02 | 2024-12-03 |
| VRx@Home: Study to Evaluate VR-therapy for PwD Living at Home HMD: Immersive VR, Tablet: Non-immersive VR - Dementia | Not applicable | Completed | University Health Network, Toronto | 7 | 2022-05-10 | 2022-10-18 |
| The Effects of Apathy on Different Forms of Fatigue Follow up and Assessment - Apathy, Fatigue | Not applicable | Completed | Centre Hospitalier Universitaire de Nice | 57 | 2021-01-14 | 2026-03-24 |
| Characterizing the Neural Bases of Motivational Disorders After Stroke Motivation tests - Stroke | Not applicable | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 66 | 2020-10-22 | 2025-02-20 |
| Move to Improve Physical Activity in Parkinson's Disease Gameficiation - Parkinson Disease, Apathy | Not applicable | Completed | University of Pennsylvania | 84 | 2019-08-26 | 2024-01-19 |
| Carbohydrate Rich Drink Reduces Pre-endoscopic Discomfort for Patients Going for Elective Endoscopic Procedures Nestle Preload, Water - Hunger, Depression | Not applicable | Completed | Tan Tock Seng Hospital | 300 | 2019-04-04 | 2024-04-10 |
| Transcranial Magnetic Stimulation for Apathy in Mild Cognitive Impairment Transcranial Magnetic Stimulation - Apathy, Mild Cognitive Impairment | Not applicable | Completed | VA Office of Research and Development | 103 | 2018-11-01 | 2026-05-22 |
| Validation of a Tool for the Dimensional Assessment of Apathy in a Population Suffering From Schizophrenia. Validate according to psychometric criteria, a dimensional measure of apathy in a population suffering from schizophrenia spectrum disorder and other psychotic disorders (according to DSM-5 criteria). - Schizophrenia | Not applicable | Completed | Centre Hospitalier de Niort | 105 | 2018-07-03 | 2020-10-23 |
| Ready, Set, Goal: Motivation and Cognition in Stroke Patients Goal-Setting Instructions, Standard Instructions - Stroke, Ischemic | Not applicable | Completed | Sunnybrook Health Sciences Centre | 72 | 2018-06-01 | 2019-10-29 |
| RCT of Efficacy of Amoxicillin Over Ampicillin on Severe Pneumonia Amoxicillin - Treatment Failure, Lethargy | Not applicable | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 308 | 2018-01-01 | 2021-07-16 |
| Assessment of Apathy in a Real-life Situation, With a Video and Sensors-based System ECOCAPTURE, Cognitive and Behavioral experimental tasks, Neuropsychological assessment - Apathy, Behavioral Variant Frontotemporal Dementia (bvFTD) | Not applicable | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 66 | 2017-09-06 | 2026-05-20 |
| Testing the Implementation of EIT-4-BPSD EIT-4-BPSD, Education-only Control - Dementia, Behavioral and Psychological Symptoms of Dementia (BPSD) | Not applicable | Completed | University of Maryland, Baltimore | 553 | 2016-04-01 | 2023-03-07 |
| Positive Emotions Program for Schizophrenia (PEPS) Positive Emotions Program for Schizophrenia, Treatment As Usual - Schizophrenia, Schizoaffective Disorder | Not applicable | Completed | Institut et Haute Ecole de la Santé la Source | 80 | 2016-02-01 | 2019-03-25 |
| Quantitative Evaluation of Apathy Close to Real Life Situation by Means of a Multimodal Sensor System Integrated. Evaluation of Apathy Close to Real Life Situation - Apathy, Behavior | Not applicable | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 14 | 2015-07-10 | 2026-06-05 |
| Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy Communication, Systematic Pain Assessment and Treatment, Medication Review - Quality of Life | Not applicable | Completed | University of Bergen | 560 | 2014-08-01 | 2016-04-15 |
Showing 20 of 27. Sign in to see all of them.
Dementia (7) · Alzheimer Disease (6) · Depression (5) · Anxiety Disorders (4) · Cognitive Dysfunction (3) · Parkinson Disease (3) · Behavior (2) · Fatigue (2) · Psychotic Disorders (2) · Schizophrenia (2) · Abdominal Pain (1) · Agnosia (1) · Alzheimer Disease 10 (1) · Anhedonia (1)
Neurobehavioral Manifestations (27) · Neurologic Manifestations (27) · Pathological Conditions, Signs and Symptoms (27) · Signs and Symptoms (27) · Nervous System Diseases (26) · Brain Diseases (17) · Central Nervous System Diseases (17) · Mental Disorders (17) · Neurocognitive Disorders (13) · Neurodegenerative Diseases (10) · Behavior (6) · Tauopathies (6) · Dementia (5) · Behavioral Symptoms (4) · Nutritional and Metabolic Diseases (4)
Therapeutics (2) · Actigraphy (1) · Advance Care Planning (1) · Amoxicillin (1) · Diet (1) · Diffusion Tensor Imaging (1) · Medication Review (1) · Methylphenidate (1) · Occupational Therapy (1) · Patient Safety (1) · Restraint, Physical (1) · Safety (1) · Smart Glasses (1) · Transcranial Magnetic Stimulation (1) · Water (1)
Centre Hospitalier Universitaire de Nice (3) · Institut National de la Santé Et de la Recherche Médicale, France (3) · Centre Hospitalier de Niort (1) · Ejdane Coskun (1) · Hasan Kalyoncu University (1) · Hospices Civils de Lyon (1) · Institut et Haute Ecole de la Santé la Source (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Martin-Luther-Universität Halle-Wittenberg (1) · Pennington Biomedical Research Center (1) · Sunnybrook Health Sciences Centre (1) · Tan Tock Seng Hospital (1) · The University of Texas Health Science Center, Houston (1) · US Department of Veterans Affairs (1) · University Health Network, Toronto (1)
France (9) · United States (9) · Canada (2) · Turkey (Türkiye) (2) · Bangladesh (1) · Germany (1) · Norway (1) · Singapore (1) · Switzerland (1)
Cyrus DeSouza, MD (2) · Antonio L Teixeira, MD (1) · Candida J Rebello (1) · Christine Gulla, MD (1) · Doris Ng, MBBS (1) · Elisabeth Flo, PysD, PhD (1) · Hubert H Fernandez, M.D. (1) · Irene Aasmul, Master (1) · Johann Behrens, PhD (1)
PMID 31551908, PMID 35751676, PMID 36155506, PMID 36658040, PMID 20113526, PMID 29078755, PMID 29370766, PMID 30564163, PMID 30706561, PMID 30783071, PMID 31064365, PMID 31267124, PMID 32748494, PMID 32753339, PMID 33467876, PMID 33851004, PMID 34253099, PMID 34275457, PMID 34551782, PMID 35608793, PMID 35653896, PMID 35700600, PMID 36324159, PMID 39345385, PMID 40482961, PMID 41284918, PMID 41330571, PMID 42837535
2017 (1), R00AG065419 (1), R01AG062685 (1)