9 completed, 5 unknown, 3 recruiting, 2 not yet recruiting. 4 Phase 4, 3 Not applicable, 2 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 4 | Completed 2, Unknown 2 |
| Not applicable | 3 | Not yet recruiting 2, Recruiting 1 |
| Phase 2 | 2 | Completed 1, Unknown 1 |
| Phase 3 | 2 | Completed 1, Terminated 1 |
| Phase 1 | 1 | Completed 1 |
Follow Left Ventricular Diastolic Dysfunction: new trials by email Literature Review of Left Ventricular Diastolic Dysfunction trials Research Report on Left Ventricular Diastolic Dysfunction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sacubitril/Valsartan Versus Valsartan Alone on Left Atrial Volume Index in Hypertensive Patients Sacubitril / Valsartan, Valsartan - Hypertension, Left Ventricular Diastolic Dysfunction | Not applicable | Not yet recruiting | University of Health Sciences Lahore | 102 | 2026-10-01 | 2026-10-02 |
| Importance of Point-of-Care Ultrasound for Early Detection of Valvular and Cardiac Diseases (IMPROVE) Kosmos Torso-One AI-guided Point-of-Care Ultrasound (EchoNous, Inc.) - Valvular Heart Disease Patients, Aortic Stenosis | Not applicable | Not yet recruiting | University of Texas Southwestern Medical Center | 1088 | 2026-08-01 | 2026-08-17 |
| The Use of Single-Beat TE-e' in Evaluation of Left Atrial Pressure in Critically Ill Patients: The TELAP-ICU Trial Echocardiography - Critical Illness, Elevated Left Atrial Pressure | Recruiting | Queen Mary Hospital, Hong Kong | 50 | 2026-07-01 | 2026-09-15 | |
| Carvedilol + Simvastatin vs. Carvedilol Alone for Cirrhosis and Cirrhotic Cardiomyopathy and Impact on Hepatic Decompensation and Survival Simvastatin 20mg, Carvedilol 3.125 mg - Decompensated Cirrhosis, Cirrhotic Cardiomyopathy | Not applicable | Recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 260 | 2025-06-10 | 2025-06-08 |
| Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome Tadalafil 5 mg, SGLT-2 inhibitor, Tadalafil plus SGLT2 inhibitors - Erectile Dysfunction, Left Ventricular Diastolic Dysfunction | Phase 4 | Completed | Kafrelsheikh University | 60 | 2025-05-05 | 2026-05-04 |
| Assessment of the Possible Association Between Left Ventricular Diastolic Dysfunction and Carotid Atherosclerosis and Brain White Matter Damage No interventions - Left Ventricular Diastolic Dysfunction | Unknown | Neuromed IRCCS | 88 | 2022-10-01 | 2022-04-11 | |
| Pediatric Hypertension and the Renin-Angiotensin SystEm (PHRASE) Hypertension, Left Ventricular Hypertrophy | Recruiting | Wake Forest University Health Sciences | 125 | 2021-05-19 | 2025-12-11 | |
| Compare the Efficacy and Safety of Rosuvastatin/Ezetimibe Combination Therapy Versus Rosuvastatin Monotherapy in Korean Patients With Left Ventricular Diastolic Dysfunction and Hyperlipidemia Rosuvastatin 20, Rosuvamibe 10/10 - Left Ventricular Diastolic Dysfunction, Hyperlipidemias | Phase 4 | Unknown | Yonsei University | 200 | 2021-01-06 | 2021-01-15 |
| Left Ventricular Diastolic Dysfunction as a Predictor of Weaning Failure From Mechanical Ventilation transthoracic echocardiography - Left Ventricular Diastolic Dysfunction, Weaning Failure | Completed | Tanta University | 48 | 2020-08-01 | 2023-02-27 | |
| Urate Lowering Therapies and Left Ventricular Diastolic Dysfunction Febuxostat 40 mg, Benzbromarone 50mg, Control - Hyperuricemia, Metabolic Syndrome | Phase 4 | Unknown | National Defense Medical Center, Taiwan | 120 | 2020-02-01 | 2020-04-28 |
| Invasive Left Heart Catheterization Registry Left heart catheterization - Heart Failure With Preserved Ejection Fraction, Left Ventricular Diastolic Dysfunction | Completed | Samsung Medical Center | 404 | 2019-12-13 | 2022-10-27 | |
| 2 New Measurements Used to Describe the Filling Phase of the Left Ventricle (LV). Diastolic Heart Failure, Left Ventricular Diastolic Dysfunction | Completed | AdventHealth | 111 | 2019-10-30 | 2023-06-29 | |
| Characterizing Patients With POAF in Relation to Cardiac Surgery by wavECG and TTE Atrial Fibrillation, Left Ventricular Diastolic Dysfunction | Active not recruiting | Helena DOMINGUEZ | 353 | 2019-10-07 | 2026-01-16 | |
| Characterization of Patients With Post-ischemic Left Ventricular Dysfunction Cardiac magnetic resonance - Left Ventricular Diastolic Dysfunction | Completed | IRCCS San Raffaele | 303 | 2018-11-18 | 2023-10-04 | |
| Hyperuricemia and Left Ventricular Diastolic Function hyperuricemia - Hyperuricemia, Metabolic Syndrome | Terminated | National Defense Medical Center, Taiwan | 67 | 2017-08-01 | 2018-04-12 | |
| Left Ventricular Diastolic Function During Anesthesia Induction Sevoflurane, Propofol - Left Ventricular Diastolic Dysfunction | Completed | Universitätsklinikum Hamburg-Eppendorf | 200 | 2017-04-01 | 2019-03-12 | |
| Personalised Prospective Comparison of ARni With ArB in Patients With Natriuretic Peptide eLEvation Sacubitril-Valsartan, Valsartan - Atrial Remodeling, Myocardial Dysfunction | Phase 2 | Unknown | Mark Ledwidge | 250 | 2015-12-16 | 2021-05-11 |
| Extended Release Exenatide Versus Placebo In Diabetic Patients With Type 4 Cardiorenal Syndrome BYDUREON, Placebo - Type 2 Diabetes Mellitus, Chronic Kidney Disease | Phase 3 | Completed | Baylor Research Institute | 57 | 2015-11-01 | 2026-02-19 |
| Diastolic Dysfunction in Patients With Type 2 Diabetes Mellitus Linagliptin, placebo - Diabetes Mellitus Type 2 (T2DM), Left Ventricular Diastolic Dysfunction | Phase 3 | Terminated | RWTH Aachen University | 8 | 2013-09-01 | 2017-04-12 |
| Cardiac Stress in Septic Shock - Biomarkers, Echocardiography and Outcome Septic Shock, Left Ventricular Systolic Dysfunction | Unknown | University Hospital, Linkoeping | 50 | 2012-10-01 | 2012-12-11 |
Showing 20 of 22. Sign in to see all of them.
Ventricular Dysfunction, Left (22) · Hypertension (4) · Hyperuricemia (3) · Metabolic Syndrome (3) · Diabetes Mellitus, Type 2 (2) · Heart Failure (2) · Acute Kidney Injury (1) · Albuminuria (1) · Aortic Valve Stenosis (1) · Atrial Fibrillation (1) · Atrial Remodeling (1) · Carotid Artery Diseases (1) · Critical Illness (1) · Diabetes Mellitus (1) · Erectile Dysfunction (1)
Cardiovascular Diseases (22) · Heart Diseases (22) · Ventricular Dysfunction (21) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Nutritional and Metabolic Diseases (7) · Metabolic Diseases (6) · Glucose Metabolism Disorders (5) · Vascular Diseases (5) · Male Urogenital Diseases (4) · Urogenital Diseases (4) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Hyperinsulinism (3) · Insulin Resistance (3)
Echocardiography (2) · Valsartan (2) · sacubitril and valsartan sodium hydrate drug combination (2) · Benzbromarone (1) · Carvedilol (1) · Exenatide (1) · Febuxostat (1) · Linagliptin (1) · Natriuretic Peptide, Brain (1) · Nebivolol (1) · Propofol (1) · Sevoflurane (1) · Simvastatin (1) · Sodium-Glucose Transporter 2 Inhibitors (1) · Tadalafil (1)
National Defense Medical Center, Taiwan (2) · AdventHealth (1) · Baylor Research Institute (1) · Helena DOMINGUEZ (1) · IRCCS San Raffaele (1) · Icahn School of Medicine at Mount Sinai (1) · Kafrelsheikh University (1) · Mark Ledwidge (1) · Mayo Clinic (1) · Neuromed IRCCS (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Queen Mary Hospital, Hong Kong (1) · RWTH Aachen University (1) · Samsung Medical Center (1) · Tanta University (1)
United States (6) · Egypt (2) · Germany (2) · South Korea (2) · Taiwan (2) · Denmark (1) · Hong Kong (1) · India (1) · Ireland (1) · Italy (1) · Sweden (1)
Cheng-Wei Liu, M.D. (2) · Andrew M South, MD, MS (1) · Dr Madhumita Premkumar, DM (1) · Fiona Ryan, Co-Investigator, PhD (1) · Helena Dominguez (1) · Horng H. Chen, M.D. (1) · Jeong Hoon Yang, MD (1) · Katharina Roeher, Dr. med. (1) · Lina De Geer, MD (1) · Mohamed G Abdelraouf, MD (1) · Nikolaus Marx, Univ.-Prof. (1) · Paolo Camici, MD, FACC (1) · Partho Sengupta, MD (1) · Peter A McCullough, MD, MPH (1) · Reda B Bastawisy, MD (Professor) (1)
PMID 16034869, PMID 16086933, PMID 17337197, PMID 17400657, PMID 19168493, PMID 19249635, PMID 19685521, PMID 19942634, PMID 20138531, PMID 20876603, PMID 21146692, PMID 21247589, PMID 21866303, PMID 21910032, PMID 23186205, PMID 23537808, PMID 24293173, PMID 24655710, PMID 24663335, PMID 24682347, PMID 25086251, PMID 25129609, PMID 25661032, PMID 25784520, PMID 25960110, PMID 26149040, PMID 26523405, PMID 26833057, PMID 26874387, PMID 27488747, PMID 27520496, PMID 27554222, PMID 27903589, PMID 27918330, PMID 28295572, PMID 28528995, PMID 28654919, PMID 28674624, PMID 28679858, PMID 29313903, PMID 29650121, PMID 33264119, PMID 36884247, PMID 36892042, PMID 38236316, PMID 42349572
2015 (1), K23HL148394 (1), P01HL076611 (1), UL1RR024150 (1)