8 completed, 5 unknown, 2 not yet recruiting, 1 active not recruiting. 8 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 8 | Completed 4, Active not recruiting 1, Not yet recruiting 1, Recruiting 1, Unknown 1 |
| Phase 4 | 1 | Completed 1 |
Follow Lactate Blood Increase: new trials by email Literature Review of Lactate Blood Increase trials Research Report on Lactate Blood Increase
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Electric Cardiometry-Guided Standard Versus Restricted Fluid Therapy In Robotic Prostaectomy Liberal Fluid Therapy, Restricted Fluid Therapy - Prostate Cancer, Surgery | Not applicable | Recruiting | Nazmy Edward Seif | 90 | 2026-06-05 | 2026-06-08 |
| Submental Tissue Oxygenation and Arterial Lactate in Major Surgery No intervention. This is a prospective observational study. Near-infrared spectroscopy measurements are performed for monitoring purposes only and do not influence clinical management. - Microcirculatory Dysfunction, Tissue Hypoperfusion | Not yet recruiting | Bursa Sevket Yilmaz Training and Research Hospital | 150 | 2026-02-15 | 2026-02-10 | |
| Effects of Different Types of Exercise on BDNF and Cognitive Performance (Exercise-BDNF) Low Exercise, Moderate-Intensity Exercise, HIIT Exercise - Exercise Training, BDNF | Not applicable | Completed | Aksaray University Training and Research Hospital | 12 | 2025-06-15 | 2026-01-30 |
| The Lactate Project: Investigating the Impact of Lactate to Preserve Vital Organ Blood Supply and Function in Heart and Brain Sodium Lactate Solution, Saline infusion (placebo) - Healthy, Lactate Blood Increase | Not applicable | Not yet recruiting | University of Aarhus | 8 | 2025-02-01 | 2024-11-01 |
| A Validation Study of the Lab Clasp Device: A Point of Care Sepsis Risk Monitor Lab Clasp - Sepsis, Sepsis Bacterial | Not applicable | Active not recruiting | Brigham and Women's Hospital | 6 | 2022-08-01 | 2026-07-16 |
| Pilot Study to Examine the Acute Impact of Veillonella Supplementation on Exercise and Lactate Responses Time to Exhaustion at velocity at VO2max - Lactate Blood Increase, Exhaustion - Physiological | Not applicable | Completed | Lindenwood University | 7 | 2022-03-30 | 2023-04-18 |
| Effects of Acute Glycerol Ingestion on Performance, Metabolic and Biochemical Markers in International Athletes PLACEBO, GLYCEROL - Performance Enhancing Product Use, Change, Body Weight | Not applicable | Completed | Francisco Javier Martínez Noguera | 4 | 2022-02-10 | 2022-03-25 |
| Saving Lives by Early Detection and Treatment of Sepsis and Septic Shock by Point of Care Lactate Test in Adults Point of care Lactate - Severe Sepsis With Septic Shock, Lactate Blood Increase | Unknown | International Centre for Diarrhoeal Disease Research, Bangladesh | 80 | 2021-10-21 | 2022-05-27 | |
| Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery arterial and central venous blood gas analysis, lactate - Congenital Heart Disease, Perioperative/Postoperative Complications | Completed | Prince of Songkla University | 136 | 2021-08-08 | 2024-03-05 | |
| Lactate Monitoring in Traumatic Long Bone Fractures Requiring Emergent Surgical Intervention Orthopedic Surgery - Lactate Blood Increase, Trauma Blunt | Completed | Arrowhead Regional Medical Center | 164 | 2021-01-01 | 2022-11-10 | |
| The Role of Lactate in Viral and Bacterial Infection viral infection, viral and bacterial infection - Viral Infection, Bacterial Infections | Completed | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 400 | 2021-01-01 | 2023-05-01 | |
| The Thiamine Administration After Cardiac Surgery Trial Thiamine 500 MG, Placebo - Lactate Blood Increase, Thiamine Deficiency | Phase 4 | Completed | Sarah Saxena | 200 | 2020-11-20 | 2022-11-17 |
| Lithothamnion Species on Blood Lactate During Exhaustive Exercise in Trained Cyclists Mineral Rich Algae, Orange flavoured water with maltodextrin as the placebo - Exercise-Induced Lactic Acidemia, Lactate Blood Increase | Not applicable | Unknown | University College Dublin | 10 | 2019-06-01 | 2019-06-10 |
| Blood Lactate Level for Pre-hospital Orientation of Septic Shock Blood sample - Sepsis, Lactate Blood Increase | Unknown | Hôpital Necker-Enfants Malades | 1000 | 2018-03-01 | 2019-02-11 | |
| Feasibility of Lactate Level Evaluation in Prehospital Care in Trauma capillary and venous lactate level measurement - Trauma, Multiple, Lactate Blood Increase | Unknown | Masaryk Hospital Usti nad Labem | 30 | 2017-05-01 | 2017-04-14 | |
| Goal-directed Fluid Therapy in Elderly Patients Undergoing Lumbar Surgery Applying goal-directed fluid therapy by continuous hemodynamic monitoring system (LiDCO） - Lactate Blood Increase, Fluid Overload | Not applicable | Completed | Peking Union Medical College Hospital | 90 | 2017-03-01 | 2021-05-18 |
| Serum Lactate in Convulsive Syncopes Compared to Non-convulsive Syncopes Lactate, prolactin and creatine kinase conc. - Syncope, Lactate Blood Increase | Unknown | RWTH Aachen University | 100 | 2017-01-01 | 2017-03-06 |
Hyperlactatemia (17) · Sepsis (3) · Edema (2) · Motor Activity (2) · Postoperative Complications (2) · Bacterial Infections (1) · Body Temperature Changes (1) · Body Weight Changes (1) · Communicable Diseases (1) · Compassion Fatigue (1) · Dehydration (1) · Heart Defects, Congenital (1) · Multiple Trauma (1) · Prostatic Neoplasms (1) · Shock, Septic (1)
Metabolic Diseases (17) · Nutritional and Metabolic Diseases (17) · Pathological Conditions, Signs and Symptoms (17) · Signs and Symptoms (17) · Pathologic Processes (5) · Infections (4) · Behavior (3) · Inflammation (3) · Systemic Inflammatory Response Syndrome (3) · Nervous System Diseases (2) · Neurologic Manifestations (2) · Water-Electrolyte Imbalance (2) · Avitaminosis (1) · Bacterial Infections and Mycoses (1) · Behavioral Symptoms (1)
Blood Specimen Collection (1) · Glycerol (1) · Lactic Acid (1) · Orthopedic Procedures (1) · Prolactin (1) · Thiamine (1) · maltodextrin (1)
Aksaray University Training and Research Hospital (1) · Arrowhead Regional Medical Center (1) · Brigham and Women's Hospital (1) · Bursa Sevket Yilmaz Training and Research Hospital (1) · Daping Hospital and the Research Institute of Surgery of the Third Military Medical University (1) · Francisco Javier Martínez Noguera (1) · Hôpital Necker-Enfants Malades (1) · International Centre for Diarrhoeal Disease Research, Bangladesh (1) · Lindenwood University (1) · Masaryk Hospital Usti nad Labem (1) · Nazmy Edward Seif (1) · Peking Union Medical College Hospital (1) · Prince of Songkla University (1) · RWTH Aachen University (1) · Sarah Saxena (1)
United States (3) · China (2) · Turkey (Türkiye) (2) · Bangladesh (1) · Belgium (1) · Denmark (1) · Egypt (1) · France (1) · Germany (1) · Spain (1) · Thailand (1)
Aldin Malkoc, MD (1) · Ashgan R Aly, M.D. (1) · Guruprasad Jambaulikar, MBBS, MPH (1) · Katy Horner, PhD (1) · MIchael Piagnerelli, MD; PHD (1) · Marcela Bilska, Dr. (1) · Michael Neeki, DO (1) · Mohamed M Mohamed, M.Sc. (1) · Nazmy S Mikhael, M.D. (1) · Oliver Matz, Dr. (1) · Romain Jouffroy, MD (1) · Shane M Heffernan, PhD (1)
PMID 15286537, PMID 17429582, PMID 17583412, PMID 19325467, PMID 19951387, PMID 20179283, PMID 20181242, PMID 20463176, PMID 20646908, PMID 22467064, PMID 23649098, PMID 24412011, PMID 25479113, PMID 26771781, PMID 27002274, PMID 27801521, PMID 28432843, PMID 29047411, PMID 30609010, PMID 30813144, PMID 39502270, PMID 40228833, PMID 42286197