5 completed, 3 recruiting, 2 unknown, 1 terminated. 5 Not applicable, 3 Phase 4, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 5 | Completed 3, Unknown 2 |
| Phase 4 | 3 | Completed 1, Recruiting 1, Terminated 1 |
| Phase 3 | 2 | Recruiting 2 |
Follow Laceration of Skin: new trials by email Literature Review of Laceration of Skin trials Research Report on Laceration of Skin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Lidocaine Versus Diphenhydramine to Achieve Local Anesthesia for Laceration Repairs Lidocaine, Diphenhydramine - Laceration of Skin | Phase 3 | Recruiting | Florida Atlantic University | 100 | 2025-09-03 | 2026-01-07 |
| Anxiolysis for Laceration Repair in Children Dexmedetomidine, Midazolam Nasal Spray, Nitrous oxide - Laceration of Skin, Distress, Emotional | Phase 3 | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 300 | 2023-12-19 | 2025-04-30 |
| IN Midazolam vs IN Dexmedetomidine vs IN Ketamine During Minimal Procedures in Pediatric ED Intranasal Midazolam, Intranasal Dexmedetomidine, Intranasal Ketamine - Laceration of Skin, Anxiety | Phase 4 | Recruiting | University of Oklahoma | 90 | 2023-11-14 | 2024-06-28 |
| Double-dorsal Versus Single-volar Digital Block Dorsal digital block, Palmar digital block - Laceration of Skin, Anesthesia, Local | Not applicable | Completed | Ankara City Hospital Bilkent | 160 | 2022-10-12 | 2024-02-23 |
| Assessment of DAFILON® Suture Material for Skin Closure Laceration of Skin, Injury Skin | Completed | Aesculap AG | 115 | 2021-03-11 | 2023-07-10 | |
| RECELL® System Combined With Meshed Autograft for Reduction of Donor Skin Harvesting in Soft Tissue Reconstruction Control Intervention (Conventional Autograft), Investigational Intervention (RECELL + more widely meshed autograft) - Full-thickness Skin Defects, Degloving Injuries | Not applicable | Completed | Avita Medical | 65 | 2020-03-02 | 2024-07-30 |
| Comparison of 2 Application Techniques for LET Gel Used Prior to Simple Laceration Repair LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (1 application), LET (lidocaine 4%; epinephrine 0.1%; tetracaine 0.5%) gel (3 applications) - LET, Laceration of Skin | Phase 4 | Completed | Children's Hospital of Orange County | 48 | 2019-06-19 | 2020-09-02 |
| Evaluation of Zip Device to Conventional Sutures for Laceration Repair in Pediatrics in an Emergency Department Zip Skin Closure Device - Laceration of Skin | Not applicable | Unknown | ZipLine Medical Inc. | 30 | 2018-11-01 | 2019-10-10 |
| IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair Ketamine, Midazolam and fentanyl - Laceration of Skin | Phase 4 | Terminated | Corewell Health East | 5 | 2018-09-04 | 2021-08-24 |
| A Post-Market Study of BandGrip in Traumatic Wound Closure Compared to Suture BandGrip, Suture - Laceration of Skin | Not applicable | Unknown | BandGrip | 45 | 2018-07-15 | 2019-07-10 |
| Virtual Reality for Anxiolysis During Laceration Repair in the Pediatric Emergency Room Virtual Reality App - Procedural Anxiety, Laceration of Skin | Not applicable | Completed | Montefiore Medical Center | 40 | 2018-04-15 | 2019-12-03 |
Agnosia (1) · Anxiety Disorders (1) · Cellulitis (1) · Crush Injuries (1) · Degloving Injuries (1) · Fasciitis, Necrotizing (1) · Infections (1) · Pain (1) · Skin Neoplasms (1) · Surgical Wound (1) · Surgical Wound Infection (1) · Wounds, Gunshot (1)
Pathological Conditions, Signs and Symptoms (4) · Neurologic Manifestations (2) · Pathologic Processes (2) · Signs and Symptoms (2) · Connective Tissue Diseases (1) · Fasciitis (1) · Infections (1) · Inflammation (1) · Mental Disorders (1) · Musculoskeletal Diseases (1) · Neoplasms (1) · Neoplasms by Site (1) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Perceptual Disorders (1)
Midazolam (2) · Dexmedetomidine (1) · Diphenhydramine (1) · Entonox (1) · Fentanyl (1) · Gels (1) · Ketamine (1) · Lidocaine (1) · Linear Energy Transfer (1) · Nitrous Oxide (1) · Sutures (1) · Tetracaine (1)
Aesculap AG (1) · Ankara City Hospital Bilkent (1) · Avita Medical (1) · BandGrip (1) · Children's Hospital of Orange County (1) · Corewell Health East (1) · Florida Atlantic University (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Montefiore Medical Center (1) · University of Oklahoma (1) · ZipLine Medical Inc. (1)
United States (7) · Canada (1) · Germany (1) · Israel (1) · Spain (1) · Turkey (Türkiye) (1)
Daniel M Fein, MD (1) · Dennis Donohoe (1) · Joshua Siembieda (1) · Kelly Levasseur, DO (1) · Ryan Mckee, MD (1) · Uri Balla, MD (1)