7 completed, 5 terminated, 5 unknown, 3 recruiting. 21 Phase 2, 8 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 21 | Completed 7, Terminated 5, Unknown 5, Recruiting 3, Suspended 1 |
| Phase 1 | 8 | Completed 3, Unknown 3, Terminated 2 |
| Phase 3 | 1 | Terminated 1 |
Follow Ischemic Cardiomyopathy: new trials by email Literature Review of Ischemic Cardiomyopathy trials Research Report on Ischemic Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PET Myocardial Fatty-acid Metabolic Imaging With XTR003 Injection and 18F-FDG to Assess Myocardial Viability in Ischemic Cardiomyopathy Fasting XTR003/¹⁸F-FDG PET myocardial metabolic imaging, Glucose-loaded ¹⁸F-FDG PET Myocardial Metabolic Imaging - Ischemic Cardiomyopathy, Heart Failure | Phase 2 | Recruiting | Sinotau Pharmaceutical Group | 40 | 2025-12-18 | 2026-03-02 |
| 18F-mFBG Imaging for Myocardial Sympathetic Innervation 18F-metaFluorobenzylguanidine, Rubidium-82 - Heart Failure, Ischemic Cardiomyopathy | Phase 2 | Recruiting | Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) | 20 | 2025-11-05 | 2026-07-01 |
| Venous Ethanol for Ventricular Tachycardia Venous ethanol, Catheter ablation - Ventricular Tachycardia, Ischemic Cardiomyopathy | Phase 2 | Recruiting | The Methodist Hospital Research Institute | 156 | 2023-04-12 | 2026-07-24 |
| Intracoronary or Intravenous Infusion Human Wharton' Jelly-derived Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy WJMSCs Vs. placebo, Placebo - Ischemic Cardiomyopathy | Phase 2 | Unknown | Navy General Hospital, Beijing | 160 | 2020-01-01 | 2019-12-05 |
| Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study Left Cardiac Sympathetic Denervation (LCSD), Optimal Medical Therapy - Dilated Cardiomyopathy, Ischemic Cardiomyopathy | Phase 2 | Suspended | University of Cape Town | 30 | 2016-11-24 | 2021-05-06 |
| Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD) umbilical cord mesenchymal stem cells - Acute Myocardial Infarction, Myocardial Infarction | Phase 1 / Phase 2 | Unknown | South China Research Center for Stem Cell and Regenerative Medicine | 64 | 2016-05-01 | 2016-01-28 |
| Therapy of Preconditioned Autologous BMMSCs for Patients With Ischemic Heart Disease BMMSCs - Myocardial Infarction, Acute Myocardial Infarction | Phase 1 / Phase 2 | Unknown | Academy Military Medical Science, China | 200 | 2015-11-01 | 2015-07-22 |
| Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure Mesenchymal Stem Cells (MSC), c-kit+ cells, Placebo (Plasmalyte A) - Ischemic Cardiomyopathy | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 125 | 2015-10-01 | 2021-04-26 |
| A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure MYDICAR Phase 1, MYDICAR Phase 2, Placebo Phase 2 only - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Celladon Corporation | 9 | 2015-04-01 | 2017-01-31 |
| Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury Manganese-enhanced MRI contrast reagent, Gadolinium-enhanced MRI contrast reagent - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 33 | 2015-04-01 | 2020-02-17 |
| AAV1-CMV-Serca2a GENe Therapy Trial in Heart Failure MYDICAR-single intracoronary infusion, Placebo; single intracoronary infusion - Heart Failure Congestive, Ischemic Cardiomyopathy | Phase 2 | Terminated | Assistance Publique - Hôpitaux de Paris | 10 | 2013-12-01 | 2017-08-29 |
| Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 6 | 2013-05-01 | 2017-01-02 |
| Allogeneic Stem Cells Implantation Combined With Coronary Bypass Grafting in Patients With Ischemic Cardiomyopathy Intramyocardial implantation of of a novel mesenchymal precursor cell type (iMP). - Coronary Artery Disease, Ischemic Cardiomyopathy | Phase 2 | Completed | AHEPA University Hospital | 11 | 2012-11-01 | 2019-05-07 |
| Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure. Allogeneic stem cells implantation - Heart Failure, Ischemic Cardiomyopathy | Phase 2 / Phase 3 | Terminated | AHEPA University Hospital | 1 | 2012-10-01 | 2022-07-25 |
| A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure AAV1/SERCA2a (MYDICAR), Placebo - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 2 | Completed | Celladon Corporation | 250 | 2012-07-01 | 2016-03-24 |
| Mesenchymal Stem Cells to Treat Ischemic Cardiomyopathy MSCs injection - Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Completed | Alexandra Cristina Senegaglia | 10 | 2010-01-01 | 2017-12-13 |
| CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy CABG combined cardiomyoplasty, CABG combined pedicled omentum graft, CABG alone - Ischemic Cardiomyopathy, Congestive Heart Failure | Phase 1 / Phase 2 | Unknown | China National Center for Cardiovascular Diseases | 70 | 2009-10-01 | 2009-12-10 |
| Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) Adult stem cells, Placebo - Chronic Ischemic Heart Disease, Left Ventricular Dysfunction | Phase 2 | Completed | The University of Texas Health Science Center, Houston | 92 | 2009-03-01 | 2015-07-01 |
| Study to Assess the Efficacy and Safety of Transplanting Autologous Skeletal Myoblasts, Into Infarcted Heart, Using an Catheter Delivery System myoblast, sham - Ischemic Cardiomyopathy | Phase 2 | Unknown | Mytogen, Inc. | 165 | 2008-03-01 | 2008-02-29 |
| Optimized Biventricular Pacing Allograft Recipients BiVP, AAI Pacing - Dilated Cardiomyopathy, Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Henry M. Spotnitz | 12 | 2007-01-01 | 2016-10-06 |
Showing 20 of 21. Sign in to see all of them.
Heart Failure (11) · Cardiomyopathies (4) · Coronary Artery Disease (4) · Myocardial Infarction (4) · Cardiovascular Diseases (3) · Heart Diseases (3) · Cardiomegaly (2) · Cardiomyopathy, Dilated (2) · Myocardial Ischemia (2) · Ventricular Dysfunction, Left (2) · Angina Pectoris (1) · Arteriosclerosis (1) · Coronary Disease (1) · Ischemia (1) · Tachycardia, Ventricular (1)
Cardiovascular Diseases (16) · Heart Diseases (16) · Vascular Diseases (10) · Pathological Conditions, Signs and Symptoms (9) · Myocardial Ischemia (8) · Pathologic Processes (6) · Arterial Occlusive Diseases (4) · Infarction (4) · Ischemia (4) · Necrosis (4) · Arteriosclerosis (3) · Coronary Disease (3) · Cardiomegaly (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Genetic Diseases, Inborn (2)
Cardiac Resynchronization Therapy (1) · Catheter Ablation (1) · Cell- and Tissue-Based Therapy (1) · Coronary Artery Bypass (1) · EVP 1001-1 (1) · Ethanol (1) · Gadolinium DTPA (1) · Inosine Monophosphate (1) · Plasmalyte A (1) · Rubidium-82 (1) · Serum Albumin, Human (1) · salicylhydroxamic acid (1)
AHEPA University Hospital (2) · Celladon Corporation (2) · Stanford University (2) · The University of Texas Health Science Center, Houston (2) · Academy Military Medical Science, China (1) · Alexandra Cristina Senegaglia (1) · Assistance Publique - Hôpitaux de Paris (1) · China National Center for Cardiovascular Diseases (1) · Genzyme, a Sanofi Company (1) · Henry M. Spotnitz (1) · Innervate Radiopharmaceuticals LLC (Formerly: Illumina Radiopharmaceuticals LLC) (1) · Mytogen, Inc. (1) · Navy General Hospital, Beijing (1) · Sinotau Pharmaceutical Group (1) · South China Research Center for Stem Cell and Regenerative Medicine (1)
United States (10) · Belgium (2) · China (2) · France (2) · Germany (2) · Greece (2) · United Kingdom (2) · Brazil (1) · Denmark (1) · Hungary (1) · Israel (1) · Italy (1) · Netherlands (1) · Poland (1) · South Africa (1)
Robert Simari, MD (2) · Henry M Spotnitz, MD (1) · K. Lance Gould, MD (1) · Kyriakos Anastasiadis, MD, PhD FETCS (1) · Kyriakos Anastasiadis, MD, PhD, FETCS (1) · Miguel Valderrabano, MD (1) · Ning K Zhang, MS (1) · Paulo Brofman, PhD (1) · Phillip C Yang, MD (1) · Phillip C. Yang, MD (1) · Shengshou Hu, MD (1)
PMID 22447880, PMID 24622121, PMID 25136078, PMID 26803443, PMID 28393439, PMID 34315432, PMID 42003602
5UM1HL087318 (1), R01HL080152 (1), U01HL087318 (1)