5 completed, 5 unknown, 3 terminated, 2 recruiting. 16 Phase 1, 8 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 16 | Completed 5, Unknown 5, Terminated 3, Recruiting 2, Withdrawn 1 |
| Phase 2 | 8 | Completed 3, Unknown 3, Terminated 2 |
Follow Ischemic Cardiomyopathy: new trials by email Literature Review of Ischemic Cardiomyopathy trials Research Report on Ischemic Cardiomyopathy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Phase I Study of Allogeneic Myocardium-Derived Mesenchymal Stem Cells (HB1011) in Patients With Ischemic Cardiomyopathy HB1011 (Allogeneic Myocardium-derived Mesenchymal Stem Cells) - Ischemic Cardiomyopathy | Phase 1 | Recruiting | HieraBio Inc. | 12 | 2026-06-23 | 2026-10-06 |
| Safety and Efficacy of FAP iCDC in Ischemic Cardiomyopathy autologus FAP-targeted immunosuppressive CAR-DCs (iCDC), Standard medical treatment - Ischemic Cardiomyopathy, Cell Therapy | Phase 1 | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 30 | 2026-05-21 | 2026-07-02 |
| Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD) umbilical cord mesenchymal stem cells - Acute Myocardial Infarction, Myocardial Infarction | Phase 1 / Phase 2 | Unknown | South China Research Center for Stem Cell and Regenerative Medicine | 64 | 2016-05-01 | 2016-01-28 |
| Therapy of Preconditioned Autologous BMMSCs for Patients With Ischemic Heart Disease BMMSCs - Myocardial Infarction, Acute Myocardial Infarction | Phase 1 / Phase 2 | Unknown | Academy Military Medical Science, China | 200 | 2015-11-01 | 2015-07-22 |
| REgenerative CardiOsphere iNjection to STRengthen dysfUnCTional Hearts Endomyocardial injections of allogeneic Human CSps, Endomyocardial injections of vehicle only. - Ischemic Cardiomyopathy, Chronic Ischemic Cardiomyopathy | Phase 1 | Withdrawn | Cedars-Sinai Medical Center | 2015-07-01 | 2014-02-12 | |
| A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure MYDICAR Phase 1, MYDICAR Phase 2, Placebo Phase 2 only - Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Celladon Corporation | 9 | 2015-04-01 | 2017-01-31 |
| Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury Manganese-enhanced MRI contrast reagent, Gadolinium-enhanced MRI contrast reagent - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 33 | 2015-04-01 | 2020-02-17 |
| Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC) Allogeneic Cardiosphere-Derived Cells (CDCs) - Dilated Cardiomyopathy (DCM), Ischemic Cardiomyopathy | Phase 1 | Unknown | Capricor Inc. | 42 | 2014-11-01 | 2016-06-21 |
| Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Ischemic Cardiomyopathy mesenchymal stem cells - Ischemic Cardiomyopathy | Phase 1 | Unknown | Hebei Medical University | 10 | 2013-10-01 | 2013-10-08 |
| Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease 'SEEMORE' - MANGANESE-ENHANCED MRI CONTRAST REAGENT - ISCHEMIC CARDIOMYOPATHY | Phase 1 / Phase 2 | Completed | Stanford University | 6 | 2013-05-01 | 2017-01-02 |
| AutoLogous Human CArdiac-Derived Stem Cell to Treat Ischemic cArdiomyopathy (ALCADIA) human cardiac stem cells - Congestive Heart Failure, Ischemic Cardiomyopathy | Phase 1 | Completed | Naofumi Takehara | 6 | 2010-04-01 | 2015-04-01 |
| Stem Cell Implantation in Patients Undergoing CABG Autologous CD133+ Bone Marrow Stem Cells, Carrier Solution - Ischemic Cardiomyopathy, Coronary Artery Disease | Phase 1 | Terminated | Miltenyi Biotec, Inc. | 23 | 2010-01-01 | 2013-12-04 |
| Mesenchymal Stem Cells to Treat Ischemic Cardiomyopathy MSCs injection - Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Completed | Alexandra Cristina Senegaglia | 10 | 2010-01-01 | 2017-12-13 |
| CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy CABG combined cardiomyoplasty, CABG combined pedicled omentum graft, CABG alone - Ischemic Cardiomyopathy, Congestive Heart Failure | Phase 1 / Phase 2 | Unknown | China National Center for Cardiovascular Diseases | 70 | 2009-10-01 | 2009-12-10 |
| Optimized Biventricular Pacing Allograft Recipients BiVP, AAI Pacing - Dilated Cardiomyopathy, Ischemic Cardiomyopathy | Phase 1 / Phase 2 | Terminated | Henry M. Spotnitz | 12 | 2007-01-01 | 2016-10-06 |
| Autologous Stem Cells for Cardiac Angiogenesis (FOCUS HF) Intramyocardial Injection of stem cells via NOGA Mapping, Control, then Stem Cell Therapy - Ischemic Cardiomyopathy | Phase 1 | Completed | Texas Heart Institute | 30 | 2004-04-01 | 2016-11-28 |
Heart Failure (6) · Myocardial Infarction (5) · Cardiovascular Diseases (4) · Heart Diseases (4) · Coronary Artery Disease (3) · Ventricular Dysfunction (3) · Cardiomyopathies (2) · Cardiomyopathy, Dilated (2) · Arteriosclerosis (1) · Cardiomegaly (1) · Coronary Disease (1) · Infarction (1) · Myocardial Ischemia (1) · Pathologic Processes (1) · Ventricular Dysfunction, Left (1)
Cardiovascular Diseases (9) · Heart Diseases (9) · Vascular Diseases (8) · Myocardial Ischemia (7) · Pathological Conditions, Signs and Symptoms (7) · Ischemia (5) · Necrosis (5) · Pathologic Processes (5) · Infarction (4) · Arterial Occlusive Diseases (3) · Arteriosclerosis (2) · Cardiomegaly (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Coronary Disease (2) · Genetic Diseases, Inborn (2)
Coronary Artery Bypass (2) · Cardiac Resynchronization Therapy (1) · Crossing Over, Genetic (1) · EVP 1001-1 (1) · Gadolinium DTPA (1) · KCB-1 protein, recombinant (1)
Stanford University (2) · Academy Military Medical Science, China (1) · Alexandra Cristina Senegaglia (1) · Capricor Inc. (1) · Cedars-Sinai Medical Center (1) · Celladon Corporation (1) · China National Center for Cardiovascular Diseases (1) · Hebei Medical University (1) · Henry M. Spotnitz (1) · HieraBio Inc. (1) · Miltenyi Biotec, Inc. (1) · Naofumi Takehara (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · South China Research Center for Stem Cell and Regenerative Medicine (1) · Texas Heart Institute (1)
United States (8) · China (3) · Brazil (1) · Japan (1) · South Korea (1)
Baoyong Yan, Doctor (1) · Deborah Ascheim, MD (1) · Eduardo Marban, MD, PhD (1) · Emerson Perin, MD,PhD. (1) · Gang Liu, Doctor (1) · Guoping Ma, Master (1) · Henry M Spotnitz, MD (1) · Hiroaki Matsubara, MD,PhD (1) · Jun Zhang, Master (1) · Paulo Brofman, PhD (1) · Phillip C Yang, MD (1) · Phillip C. Yang, MD (1) · Shengshou Hu, MD (1)
R01HL080152 (1), R44HL095203 (1)