14 terminated. 14 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 14 | Terminated 14 |
| Phase 2 | 7 | Terminated 7 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study to Compare the Pharmacokinetics and Pharmacodynamics of ASA Powder for Oral Inhalation With Non-enteric-coated Chewable Aspirin in Adult Subjects With Obstructive or Restrictive Pulmonary Function single dose (100 mg) of ASA, single dose (162 mg) of non-enteric-coated chewable aspirin tablets - Obstructive Pulmonary Function, Restrictive Pulmonary Function | Phase 1 | Terminated | Vectura, Inc. | 4 | 2023-03-11 | 2024-03-22 |
| YQ23 Study in Patients With Critical Limb Ischaemia YQ23, Matching placebo - Critical Limb Ischemia | Phase 1 / Phase 2 | Terminated | New Beta Innovation Limited | 5 | 2021-03-10 | 2023-12-08 |
| Allogeneic Heart Stem Cells to Achieve Myocardial Regeneration CAP-1002 Allogeneic Cardiosphere-Derived Cells, Placebo - Myocardial Infarction | Phase 1 / Phase 2 | Terminated | Capricor Inc. | 135 | 2012-11-13 | 2024-04-09 |
| Clinical Trial I/II Opened, Randomized and Controlled for the Study of the Use of Stem Cells Therapy in Insulinized Diabetic Patients Type 2 With Critical Ischemia in Lower Limbs (CLI): Study of the Needs of Insulin Stem cell infusion - Critical Limb Ischemia (CLI) | Phase 1 / Phase 2 | Terminated | Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud | 20 | 2011-09-01 | 2018-12-19 |
| Autologous Cell Therapy for Ischemic Heart Failure AMDC - Ischemic Heart Disease | Phase 1 / Phase 2 | Terminated | Cook MyoSite | 9 | 2011-02-05 | 2021-07-01 |
| Study of 2.0 mg Ranibizumab in Subjects With Ischemic Central Retinal Vein Occlusion (RAVE2) ranibizumab - Ischemia, Retinal Vein Occlusion | Phase 1 | Terminated | David M. Brown, M.D. | 8 | 2010-10-01 | 2017-08-14 |
| The Effects of Lovaza® in Acute Myocardial Infarction Lovaza®, The placebo contained 1 gram of corn oil in each capsule. - Myocardial Infarction | Phase 1 / Phase 2 | Terminated | University of Rochester | 4 | 2010-06-01 | 2017-11-06 |
| Efficacy and Safety of Umbilical Cord Blood Injection for Critical Limb Ischemia Cord blood stem cell injection - Critical Limb Ischemia | Phase 1 | Terminated | Richard Burt, MD | 1 | 2009-11-01 | 2014-02-03 |
| Safety Study of Adult Stem Cells to Treat Patients With Severe Leg Artery Disease autologous CD133+ cells - Critical Limb Ischemia, Arterial Occlusive Disease | Phase 1 | Terminated | University of Wisconsin, Madison | 10 | 2009-05-01 | 2014-12-05 |
| Effects of Intracoronary Progenitor Cell Therapy on Coronary Flow Reserve After Acute MI autologous bone marrow-derived progenitor cells, placebo medium - Coronary Artery Disease, Acute Myocardial Infarction | Phase 1 / Phase 2 | Terminated | Johann Wolfgang Goethe University Hospital | 31 | 2008-09-01 | 2017-01-12 |
| Stem Cell Study for Subjects With Congestive Heart Failure Intramyocardial injection of autologous CD34-positive cells (stem cells) - Myocardial Ischemia, Congestive Heart Failure | Phase 1 | Terminated | Losordo, Douglas, M.D. | 4 | 2008-03-01 | 2015-03-31 |
| Stem Cell Study for Patients With Heart Disease Autologous peripheral blood CD34 positive cell therapy - Chest Pain, Chronic Myocardial Ischemia | Phase 1 / Phase 2 | Terminated | Foundation for Biomedical Research and Innovation | 1 | 2005-09-01 | 2011-06-22 |
| AMP as a Better Delivery System of Adenosine Adenosine, Adenosine Mono Phosphate (AMP) - Ischemia | Phase 1 | Terminated | Vanderbilt University Medical Center | 13 | 2003-10-01 | 2019-05-07 |
| BELIEVE Study: Nesiritide and Post Myocardial Infarction Left Ventricular Modeling Human BNP - Myocardial Infarction | Phase 1 | Terminated | Mayo Clinic | 24 | 2002-08-01 | 2009-12-11 |
Myocardial Infarction (7) · Chronic Limb-Threatening Ischemia (4) · Heart Failure (3) · Coronary Artery Disease (2) · Heart Diseases (2) · Myocardial Ischemia (2) · Vascular Diseases (2) · Acute Coronary Syndrome (1) · Angina Pectoris (1) · Arterial Occlusive Diseases (1) · Bites and Stings (1) · Cardiomyopathies (1) · Cardiovascular Diseases (1) · Chest Pain (1)
Pathological Conditions, Signs and Symptoms (14) · Pathologic Processes (13) · Cardiovascular Diseases (12) · Vascular Diseases (11) · Infarction (8) · Necrosis (8) · Arteriosclerosis (6) · Heart Diseases (6) · Myocardial Ischemia (6) · Arterial Occlusive Diseases (5) · Chronic Disease (5) · Disease Attributes (5) · Atherosclerosis (4) · Peripheral Arterial Disease (4)
Adenosine (1) · Adenosine Monophosphate (1) · Corn Oil (1) · Fish Oils (1) · Omacor (1) · Ranibizumab (1) · beta-apocarotenoid-14',13'-dioxygenase (1)
Andalusian Initiative for Advanced Therapies - Fundación Pública Andaluza Progreso y Salud (1) · Capricor Inc. (1) · Cook MyoSite (1) · David M. Brown, M.D. (1) · Foundation for Biomedical Research and Innovation (1) · Johann Wolfgang Goethe University Hospital (1) · Losordo, Douglas, M.D. (1) · Mayo Clinic (1) · New Beta Innovation Limited (1) · Richard Burt, MD (1) · University of Rochester (1) · University of Wisconsin, Madison (1) · Vanderbilt University Medical Center (1) · Vectura, Inc. (1)
United States (9) · Canada (1) · Germany (1) · Hong Kong (1) · Japan (1) · Spain (1)
Amish N Raval, MD (1) · Andreas M Zeiher, MD (1) · Bernat Soria (1) · Billy Lau (1) · Charles C Wykoff, MD, PhD (1) · Douglas W. Losordo, M.D. (1) · Frank Litvack, MD (1) · Horng H. Chen, M.D. (1) · Hung Q. Ly, MD (1) · Italo Biaggioni, M.D. (1) · Richard Burt, MD (1) · Robert Block, MD, MPH (1) · Takayuki Asahara, M.D. (1)
PMID 25102193, PMID 25239491, PMID 32749459, PMID 34233913, PMID 35802393
RC3HL103356-01 (1)