37 completed, 7 unknown, 3 withdrawn, 2 recruiting. 22 Not applicable, 14 Phase 2, 7 Phase 4, 6 Phase 3, 3 Phase 1.
Follow Irritable Bowel Syndrome With Diarrhea: new trials by email Literature Review of Irritable Bowel Syndrome With Diarrhea trials Research Report on Irritable Bowel Syndrome With Diarrhea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Mechanistic Evaluation of Hewei Anchang Formula for Overlapping Gastrointestinal Symptoms in Patients With Coexisting Functional Dyspepsia and Diarrhea-Predominant Irritable Bowel Syndrome Hewei Anchang Formula Granules, Hewei Anchang Formula Matching Placebo Granules - Functional Dyspepsia, Irritable Bowel Syndrome With Diarrhea | Not applicable | Not yet recruiting | Xiyuan Hospital of China Academy of Chinese Medical Sciences | 120 | 2027-01-01 | 2026-07-20 |
| Efficacy and Safety of FMT for the Treatment of IBS-D and Mental Health Comorbidity in Young Adults Fecal Microbiota Transplantation, Placebo - Irritable Bowel Syndrome With Diarrhea, Fecal Microbiota Transplantation | Phase 2 | Unknown | Shenzhen Hospital of Southern Medical University | 88 | 2024-09-01 | 2024-07-16 |
| The Effect of Dietary Supplementation on Intestinal Barrier Function in IBS-D Lactulose/Mannitol Ratio Test, Serum biomarkers of intestinal permeability, Rome IV questionnaire - Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | Dr Anthony Hobson | 32 | 2024-08-01 | 2025-06-24 |
| Effects of the Multispecies Probiotic Ecologic Barrier in IBS Patients With Upper GI Symptoms and Anxiety, Depression, or Stress Ecologic Barrier - Irritable Bowel Syndrome With Diarrhea | Not applicable | Recruiting | Institute of Gastroenterology and Hepatology, Vietnam | 60 | 2024-06-01 | 2026-06-18 |
| B.Subtilis Attenuate Symptoms in Diarrhea-predominant Irritable Bowel Syndrome by Increasing Hypoxanthine Biosynthesis B. subtilis, Dead B. subtilis - Irritable Bowel Syndrome with Diarrhea, Purine Metabolism Disorder | Early Phase 1 | Unknown | Jinling Hospital, China | 180 | 2024-06-01 | 2024-09-25 |
| A Study to Evaluate the Efficacy and Safety of Live SK08 Powder in Patients With IBS-D Live SK08 powder, Placebo - Irritable Bowel Syndrome With Diarrhea | Phase 3 | Recruiting | Guangzhou Zhiyi Biotechnology Co., Ltd. | 1298 | 2024-03-16 | 2025-04-03 |
| Effect of Consuming a Nutraceutical Composition on Signs and Symptoms in Adult Patients With Irritable Bowel Syndrome Ananá - Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea | Not applicable | Enrolling by invitation | Universidad Autonoma de Nuevo Leon | 94 | 2024-03-14 | 2025-09-02 |
| Evaluation of Butyrate and Palmitoylethanolamide in IBS Patients (B/P3_1) ButirBioma + PeaBioma, Placebo - Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | University of Padova | 50 | 2024-03-08 | 2025-07-10 |
| Study of the Research Medicine CIN-103 in Adults With Irritable Bowel Syndrome With Predominant Diarrhea (IBS-D). CIN-103, Placebo - Irritable Bowel Syndrome With Diarrhea | Phase 2 | Terminated | CinPhloro Pharma, LLC | 421 | 2023-12-28 | 2025-12-15 |
| Safety and Efficacy of a Probiotic Supplement in IBS-D Probiotic, Placebo - Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome | Not applicable | Completed | The Archer-Daniels-Midland Company | 46 | 2023-06-06 | 2025-03-06 |
| Self- Administered Acupressure for Diarrhea Predominant Irritable Bowel Syndrome Active acupressure, Sham acuptressure - Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | Alexandria University | 70 | 2023-02-05 | 2024-04-30 |
| Efficacy and Safety of DT01 Tablets in Patients With Irritable Bowel Syndrome With Diarrhea DT01 tablets, Placebo tablets, DT01-Placebo tablets - Irritable Bowel Syndrome With Diarrhea | Phase 2 | Unknown | Centre of Clinical Pharmacology, Hanoi Medical University | 120 | 2023-02-01 | 2023-02-09 |
| To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea Rifaximin 550 MG, Mebeverine 135 MG, Psyllium Husk - Irritable Bowel Syndrome With Diarrhea | Phase 4 | Completed | Bahria University | 162 | 2023-01-03 | 2023-07-27 |
| Personalized Dietary Intervention Based on Microbiome Analysis vs FODMAP Diet for Irritable Bowel Syndrome Personalized dietary intervention based on microbiome analysis, Low-FODMAP diet - Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea | Not applicable | Unknown | Istanbul Medipol University Hospital | 100 | 2022-10-01 | 2022-12-12 |
| Probiotics as Adjuvant Therapy in the Management of Irritable Bowel Syndrome Two probiotic strains (L. plantarum and L. acidophilus) - Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | University of Mosul | 100 | 2022-07-19 | 2023-01-18 |
| Comparing the Efficacy of Nitazoxanide Versus Rifaximin in Adult Patients With Irritable Bowel Syndrome Without Constipation Nitazoxanide 500Mg Oral Tablet, Rifaximin 550Mg Tab - Irritable Bowel Syndrome With Diarrhea | Phase 1 / Phase 2 | Withdrawn | Sadat City University | 2022-07-01 | 2025-07-14 | |
| Evaluating the Safety and Efficacy of the Probiotic Bifidobacterium Longum ES1 and the Post Biotic Heat-treated Bifidobacterium Longum ES1 (HT-ES1) on IBS Symptom Severity in Patients With Diarrhoea Predominant Irritable Bowel Syndrome ES 1, HT ES1, Placebo - Irritable Bowel Syndrome With Diarrhea | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 200 | 2022-04-21 | 2023-09-08 |
| Aldafermin (NGM282) for Chronic Diarrhea Due to Bile Acid Malabsorption (BAM) Aldafermin, Placebo - Chronic Diarrhea, Irritable Bowel Syndrome With Diarrhea | Phase 2 | Completed | Michael Camilleri, MD | 30 | 2021-12-01 | 2023-10-12 |
| GI Permeability Change in Response to Aquamin® Aquamin - Ulcerative Colitis, Healthy | Phase 2 | Completed | James Varani | 35 | 2021-11-02 | 2026-07-17 |
| Study on the Molecular Mechanism of Diarrhea-predominant Irritable Bowel Syndrome With Anxiety and Depression Based on Multi-omics Correlation Analysis Endoscopy - Irritable Bowel Syndrome With Diarrhea | Unknown | Tang-Du Hospital | 15 | 2021-11-01 | 2022-04-05 |
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Irritable Bowel Syndrome (18) · Diarrhea (6) · Intestinal Diseases (4) · Abdominal Pain (2) · Anxiety Disorders (1) · Colitis, Ulcerative (1) · Depression (1) · Fecal Incontinence (1) · Gastrointestinal Diseases (1) · Ichthyosis Bullosa of Siemens (1) · Mucositis (1)
Digestive System Diseases (20) · Colonic Diseases (19) · Gastrointestinal Diseases (19) · Colonic Diseases, Functional (18) · Intestinal Diseases (15) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Signs and Symptoms, Digestive (7) · Gastroenteritis (2) · Neurologic Manifestations (2) · Pain (2) · Behavior (1) · Behavioral Symptoms (1) · Colitis (1) · Congenital Abnormalities (1)
Rifaximin (6) · Sugars (4) · ibodutant (4) · Fecal Microbiota Transplantation (2) · Psyllium (2) · eluxadoline (2) · 6-methylbenzo(b)thiophene-2-carboxylic acid (1-(2-phenyl-((1-(tetrahydropyran-4-ylmethyl)piperidin-4-ylmethyl)carbamoyl)ethylcarbamoyl)cyclophenyl)amide (1) · Acetylcysteine (1) · Amitriptyline (1) · Aquamin (1) · Colesevelam Hydrochloride (1) · Colonoscopy (1) · Diet Records (1) · Diet Therapy (1) · Dietary Supplements (1)
Menarini Group (4) · Allergan (2) · Bausch Health Americas, Inc. (2) · Vedic Lifesciences Pvt. Ltd. (2) · Xiyuan Hospital of China Academy of Chinese Medical Sciences (2) · AGI Therapeutics, Inc. (1) · Alexandria University (1) · Amorepacific Corporation (1) · Attikon Hospital (1) · Bahria University (1) · Cedars-Sinai Medical Center (1) · Centre of Clinical Pharmacology, Hanoi Medical University (1) · Children's Memorial Health Institute, Poland (1) · CinPhloro Pharma, LLC (1) · Dr Anthony Hobson (1)
United States (18) · China (7) · Czechia (4) · Germany (4) · Poland (4) · United Kingdom (4) · Italy (3) · Russia (3) · Sweden (3) · Bulgaria (2) · Canada (2) · Egypt (2) · France (2) · India (2) · Mexico (2)
Jan Tack, Professor (2) · Lin Chang, Professor (2) · Anna Muslin (1) · Dr. Ramesh Dargad (1) · Edoardo Savarino, Prof,MD (1) · Enoch Bortey, PhD (1) · Esther Jo (1) · Guy Boeckxstaens, M.D. (1) · James Varani (1) · Jan F Tack, Prof. (1) · Jan F Tack, Professor (1) · Jonghwa Roh, PhD (1) · Konstantinos Triantafyllou (1) · Kyle Staller, MD MPH (1)
PMID 26071133, PMID 27196574, PMID 27528177, PMID 27795384, PMID 28589238, PMID 28932270, PMID 29708822, PMID 32088296, PMID 33652763, PMID 34115808, PMID 35288511, PMID 35704960, PMID 35760542, PMID 36114762, PMID 36922331, PMID 38717025, PMID 38892525, PMID 39875940, PMID 40362860, PMID 41359652, PMID 41646788, PMID 41887552, PMID 42440705
2017 (1), R01DK115950 (1), UL1TR000135 (1)