3 completed, 2 active not recruiting, 1 recruiting, 1 withdrawn. 7 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 7 | Completed 3, Active not recruiting 2, Recruiting 1, Withdrawn 1 |
Follow Insulin Sensitivity: new trials by email Literature Review of Insulin Sensitivity trials Research Report on Insulin Sensitivity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus Retatrutide, Semaglutide, Placebo - Diabetes Mellitus, Insulin Sensitivity | Phase 1 | Active not recruiting | Eli Lilly and Company | 95 | 2025-06-02 | 2026-10-06 |
| Aging Resilience Through Microbiota Optimization and Regulation FMT capsule, Placebo Capsule(s) - Resilience, Cognitive Function and Well-Being | Phase 1 | Active not recruiting | Gonzalo Jorquera, PhD | 80 | 2025-01-10 | 2026-07-29 |
| MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution - Type 1 Diabetes, Diabetic Kidney Disease | Phase 1 | Recruiting | Kalie Tommerdahl | 60 | 2022-07-01 | 2025-06-13 |
| Metabolic Effects of Melatonin Treatment Melatonin, Placebo Oral Tablet - Metabolic Disease, Insulin Sensitivity | Phase 1 | Completed | University of Aarhus | 17 | 2019-09-26 | 2021-08-25 |
| Racial Differences in Vagal Control of Glucose Homeostasis, Chronic Study Galantamine, Placebo - Insulin Sensitivity, Oxidative Stress | Phase 1 | Withdrawn | Vanderbilt University Medical Center | 2017-01-01 | 2018-08-13 | |
| Effect of Vitamin D Replacement on Insulin Sensitivity Ergocalciferols, Placebo - Insulin Sensitivity | Phase 1 | Completed | Texas Tech University Health Sciences Center | 12 | 2011-01-01 | 2015-06-08 |
| Mechanism of Insulin-Resistant in Lean Non-Diabetics exercise, Non exercise - Insulin Resistance, Insulin Sensitivity | Phase 1 | Completed | University of California, San Francisco | 149 | 2004-02-01 | 2014-01-23 |
Insulin Resistance (7) · Diabetes Mellitus, Type 2 (2) · Cardiovascular Diseases (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Diabetic Nephropathies (1) · Glucose Metabolism Disorders (1) · Inflammation (1) · Metabolic Diseases (1) · Obesity (1) · Vitamin D Deficiency (1)
Hyperinsulinism (7) · Nutritional and Metabolic Diseases (7) · Glucose Metabolism Disorders (6) · Metabolic Diseases (6) · Endocrine System Diseases (4) · Diabetes Mellitus (3) · Nutrition Disorders (2) · Pathological Conditions, Signs and Symptoms (2) · Autoimmune Diseases (1) · Avitaminosis (1) · Body Weight (1) · Deficiency Diseases (1) · Diabetes Complications (1) · Female Urogenital Diseases (1) · Female Urogenital Diseases and Pregnancy Complications (1)
Ergocalciferols (1) · Exercise (1) · Fecal Microbiota Transplantation (1) · Galantamine (1) · Injections (1) · Iohexol (1) · Melatonin (1) · Metformin (1) · p-Aminohippuric Acid (1) · retatrutide (1) · semaglutide (1)
Eli Lilly and Company (1) · Gonzalo Jorquera, PhD (1) · Kalie Tommerdahl (1) · Texas Tech University Health Sciences Center (1) · University of Aarhus (1) · University of California, San Francisco (1) · Vanderbilt University Medical Center (1)
United States (4) · Chile (1) · Denmark (1) · Germany (1)
Cyndya A Shibao, MD (1) · Esben Stistrup Lauritzen, MD (1) · Gonzalo Jorquera, PhD (1) · Ricardo Espinoza, MD (1) · Ulla Kampmann Opstrup, MD, PhD (1) · Vinaya Simha, MD (1)
2019 (1), K23HL159292 (1), R01DK059358 (1)