10 completed, 4 unknown, 3 recruiting, 1 active not recruiting. 6 Not applicable, 6 Phase 2, 3 Phase 1, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 2, Unknown 2, Active not recruiting 1, Recruiting 1 |
| Phase 2 | 6 | Completed 4, Recruiting 1, Unknown 1 |
| Phase 1 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 3 | Completed 3 |
Follow Indigestion: new trials by email Literature Review of Indigestion trials Research Report on Indigestion
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Trial to Evaluate the Effects of a Fibre Supplement on Microbiome and Gut Health Essential Fibre+ - Gut Health, Microbiome | Not applicable | Active not recruiting | Artah Nutrition Limited | 50 | 2026-06-01 | 2026-08-24 |
| A Clinical Study to Assess the Effectiveness of ENO Lime in Participants With Ajeerna Vyadhi (Acidity, Acid Indigestion, Indigestion, and Associated Nausea) ENO Lime - Indigestion Acid, Indigestion | Phase 3 | Completed | HALEON | 40 | 2025-08-20 | 2025-09-17 |
| A Prospective Multicentre Real-world Assessment of the Efficacy of Danning Tablets in Alleviating Digestive Symptoms Danning Tablet - Indigestion, Dyspepsia | Recruiting | Shanghai Hutchison Pharmaceuticals Limited | 4500 | 2025-04-30 | 2025-05-14 | |
| Clinical Study of De-Stress & Happy Gut Powder for Stress and Indigestion in Adults. De-stress & happy gut powder-U001, De-Stress & Happy Gut powder-I001, Placebo Powder 001 - Stress, Dyspepsia | Not applicable | Unknown | Herbolab India Pvt. Ltd. | 81 | 2024-09-05 | 2024-08-23 |
| The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients traditional Chinese medicine, Routine ICU care, historical Routine ICU care - Organ Failure, Multiple, Indigestion | Not applicable | Recruiting | China Medical University Hospital | 350 | 2024-05-07 | 2024-06-11 |
| A First-in-Human Study to Learn How Well a Bi-Layer Calcium Carbonate Antacid Tablet Works Compared to a Standard, Non-Layered Calcium Carbonate Tablet in Healthy Male Participants bi-layer calcium carbonate tablet (BAY1180654), Immediate release calcium carbonate tablet (BAY1180654) - Heartburn, Indigestion | Phase 1 | Completed | Bayer | 21 | 2024-03-06 | 2024-07-03 |
| Benchtop NMR Spectroscopy for Assessment of Clinical Human Pathologies (BRANCH-P STUDY) Diabetes, Chronic Kidney Diseases | Unknown | Willows Health | 2000 | 2023-01-01 | 2022-08-15 | |
| Efficacy of a Digestive Enzyme Blend Digestive enzyme blend, Placebo - Digestive Health, Indigestion | Not applicable | Unknown | Deerland Enzymes | 50 | 2021-05-10 | 2021-06-08 |
| Upset Stomach Relief for Mild and Moderate Indigestion and Heartburn HLNatural, Inc. Upset Stomach Relief - Indigestion, Heartburn | Not applicable | Completed | Hawthorne Effect Inc. | 161 | 2019-10-16 | 2021-11-15 |
| Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia Ondansetron 8mg, Placebo - Indigestion, Diabetes Mellitus | Phase 2 | Recruiting | Mayo Clinic | 150 | 2019-04-02 | 2026-05-04 |
| Trial to Reduce Inappropriate Oesophagogastroduodenoscopies for Dyspepsia e-learning - Dyspepsia, Indigestion | Not applicable | Completed | Radboud University Medical Center | 119 | 2017-11-20 | 2019-06-26 |
| Probiotic Supplementation Among Adults With Recurrent Gastrointestinal Symptoms Probiotic dietary supplement (Trenev Trio®), placebo - Gastrointestinal Symptoms, Bloating | Phase 2 / Phase 3 | Completed | University of Maryland, Baltimore | 80 | 2014-12-01 | 2021-09-14 |
| Efficacy of a Dietary Supplementation With Lactobacillus Reuteri for Digestive Health in an Elderly Population Placebo, Lactobacillus reuteri DSM 17938 - Constipation, Diarrhea | Phase 3 | Completed | Örebro University, Sweden | 290 | 2013-04-01 | 2014-12-05 |
| Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE. Secretol, Nexium - Gastroesophageal Reflux Disease (GERD), Heartburn | Phase 1 / Phase 2 | Unknown | Effexus Pharmaceutical | 40 | 2010-05-01 | 2014-08-05 |
| NAET Screening for Food Allergy, Sensitivity and Intolerances Using IgE-Specific Antigen Test and NST- NAET® NAET Procedures - Food Sensitivities, Headache | Completed | Nambudripad's Allergy Research Foundation | 42 | 2005-07-01 | 2006-11-01 | |
| NAET® Testing Devices in Detection of Hypersensitivity to Cane Sugar NAET Testing Modalities - Allergy, Fatigue | Phase 1 / Phase 2 | Completed | Nambudripad's Allergy Research Foundation | 75 | 2005-01-01 | 2008-10-17 |
| YM443 in Subjects With Functional Dyspepsia YM443 - Indigestion, Nausea | Phase 2 | Completed | Astellas Pharma Inc | 416 | 2004-03-10 | 2018-01-10 |
| Inhibition of Gastric Acid is the Key to Satisfactory Relief of Symptoms With Esomeprazole in NUD Patients Esomeprazole, Placebo - Indigestion | Phase 2 | Completed | University of Kansas Medical Center | 73 | 2003-10-01 | 2019-11-27 |
Dyspepsia (18) · Abdominal Pain (3) · Constipation (3) · Gastroesophageal Reflux (3) · Heartburn (3) · Diabetes Mellitus (2) · Diarrhea (2) · Eczema (2) · Hypersensitivity (2) · Nausea (2) · Acne Vulgaris (1) · Acquired Immunodeficiency Syndrome (1) · Alzheimer Disease (1) · Anorexia (1) · Appendicitis (1)
Pathological Conditions, Signs and Symptoms (18) · Signs and Symptoms (18) · Signs and Symptoms, Digestive (18) · Digestive System Diseases (5) · Gastrointestinal Diseases (5) · Neurologic Manifestations (5) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Pain (4) · Deglutition Disorders (3) · Esophageal Diseases (3) · Esophageal Motility Disorders (3) · Glucose Metabolism Disorders (3) · Immune System Diseases (3) · Skin and Connective Tissue Diseases (3)
Esomeprazole (2) · Lansoprazole (1) · Medicine, Chinese Traditional (1) · Ondansetron (1)
Nambudripad's Allergy Research Foundation (2) · Artah Nutrition Limited (1) · Astellas Pharma Inc (1) · Bayer (1) · China Medical University Hospital (1) · Deerland Enzymes (1) · Effexus Pharmaceutical (1) · HALEON (1) · Hawthorne Effect Inc. (1) · Herbolab India Pvt. Ltd. (1) · Mayo Clinic (1) · Radboud University Medical Center (1) · Shanghai Hutchison Pharmaceuticals Limited (1) · University of Kansas Medical Center (1) · University of Maryland, Baltimore (1)
United States (9) · United Kingdom (2) · China (1) · India (1) · Netherlands (1) · Sweden (1) · Taiwan (1)
Adil E Bharucha, MD (1) · Chris D'Adamo, PhD (1) · Devi S Nambudripad, DC,L.Ac,PhD (1) · Devi S Nambudripad, DCLAcPhD (1) · Dr. Ramshyam Agarwal, MBBS, DNB (1) · Jerzy Sarosiek, PhD (1) · Philippe B Wilson (1) · Prof. Dr. Drenth, MD, PhD (1) · Prof. Dr. Masclee, MD, PhD (1) · Richard Mccallum, MD (1) · Rishabh Prasad (1) · Robert Jan Brummer, MD, PhD (1) · Ronnie Fass, MD (1)
P01DK068055 (1)