8 completed, 2 terminated, 1 unknown. 11 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 11 | Completed 8, Terminated 2, Unknown 1 |
| Phase 2 | 4 | Completed 2, Terminated 1, Unknown 1 |
Follow Immunosuppression: new trials by email Literature Review of Immunosuppression trials Research Report on Immunosuppression
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| High-Dose Moderna mRNA-1273 Booster Study for Lung Transplant Recipients mRNA-1273 (Moderna COVID-19 vaccine) - Lung Transplant Recipient, SARS-CoV-2 | Phase 1 / Phase 2 | Terminated | University of California, Los Angeles | 19 | 2022-03-10 | 2025-03-26 |
| Clinical Trial for Assessment of Anti-SARS-CoV-2 Serum for Early Treatment of COVID-19 Cases AntiSARS-CoV-2 Serum, Placebo - Immunosuppression, Cancer | Phase 1 / Phase 2 | Unknown | Butantan Institute | 618 | 2021-05-01 | 2021-04-08 |
| Effect of RANKL Inhibition on UV-induced Immunosuppression Denosumab, UVB exposure, Diphenylcyclopropenone - Ultraviolet Rays, Immunosuppression | Phase 1 | Completed | Innovaderm Research Inc. | 31 | 2013-11-01 | 2014-07-24 |
| Cardiac Allograft Remodeling and Effects of Sirolimus Cardiac MRI, Coronary angiography with IVUS, Cardiac Allograft Remodeling - Cardiac Hypertrophy, Immunosuppression | Phase 1 | Terminated | University of Nebraska | 42 | 2013-04-24 | 2023-08-30 |
| Extracorporeal Photopheresis in Liver Transplantation. Phase II Clinical Trial in Safety and Efficacy in Patients With Gradual Decrease of Immunosuppression. Extracorporeal Photopheresis Procedure (FEC) - Liver Transplantation, Immunosuppression | Phase 1 / Phase 2 | Completed | Red de Terapia Celular | 10 | 2013-04-01 | 2017-03-30 |
| Safety of Immunosuppression Minimization in Children and Adolescents After Kidney Transplantation Sirolimus, MMF or Azathioprine - Kidney Failure, Chronic, Kidney Transplantation | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 7 | 2009-05-01 | 2013-02-15 |
| Pharmacokinetic Drug Interaction Between Ezetimibe and Tacrolimus After Single Dose Administration in Healthy Subjects 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany, 1 capsule Prograf(R) (tacrolimus), Astellas Pharma GmbH, Germany, 1 tablet Ezetrol(R) + 1 capsules Prograf(R) - Pharmacokinetics, Drug Interactions | Phase 1 | Completed | University Medicine Greifswald | 24 | 2007-09-01 | 2008-02-22 |
| Pharmacokinetic Drug Interaction Between Ezetimibe and Sirolimus After Single Dose Administration in Healthy Subjects 1 tablet Ezetrol(R) (ezetimibe), MSD Sharp & Dohme GmbH, Germany, 1 tablet Rapamune(R) (sirolimus), Wyeth Pharma, Germany, 1 tablet Ezetrol(R) + 1 tablet Rapamune(R) - Pharmacokinetics, Drug Interactions | Phase 1 | Completed | University Medicine Greifswald | 24 | 2007-04-01 | 2008-02-22 |
| Randomized Controlled Trial in Liver Transplant Recipients Treated in Steroid Sparing Regimen Neoral, Tacrolimus - Chronic Hepatitis C, Organ Transplantation | Phase 1 | Completed | Duke University | 40 | 2006-02-01 | 2014-09-22 |
| Cholesterol and Fatty Acid Synthesis in Islet and Liver Transplant Patients and Effect of Dietary Intervention Dietary intervention - supplements - Immunosuppression, Hyperlipidemias | Phase 1 / Phase 2 | Completed | University of Alberta | 46 | 2005-11-01 | 2009-07-28 |
| To Demonstrate the Relative Bioavailability of Hydroxychloroquine Sulfate, 200 mg Tablets Hydroxychloroquine Sulfate Tablets, 200 mg (Geneva Pharmaceutical, Inc.), Hydroxychloroquine Sulfate Tablets, 200 mg, Plaquenil (Sanofi Winthrop) - Immunosuppression, Rheumatism | Phase 1 | Completed | Sandoz | 72 | 1993-07-01 | 2017-03-28 |
Hypercholesterolemia (2) · COVID-19 (1) · Cardiomegaly (1) · Cardiovascular Diseases (1) · Dermatitis, Allergic Contact (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 1 (1) · Hepatitis C, Chronic (1) · Hyperlipidemias (1) · Hypersensitivity, Delayed (1) · Kidney Diseases (1) · Kidney Failure, Chronic (1) · Neoplasms (1) · Pulmonary Disease, Chronic Obstructive (1) · Renal Insufficiency (1)
Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Chronic Disease (3) · Disease Attributes (3) · Dyslipidemias (3) · Lipid Metabolism Disorders (3) · Pathologic Processes (3) · Endocrine System Diseases (2) · Female Urogenital Diseases (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Glucose Metabolism Disorders (2) · Hyperlipidemias (2) · Immune System Diseases (2) · Infections (2)
Sirolimus (3) · Ezetimibe (2) · Tacrolimus (2) · 2019-nCoV Vaccine mRNA-1273 (1) · Azathioprine (1) · Cyclosporine (1) · Denosumab (1) · Exercise Test (1) · FEC protocol (1) · Hydroxychloroquine (1) · RulB protein, Pseudomonas syringae (1) · Saline Solution (1) · Sodium Chloride (1) · Trifyba (1) · diphenylcyclopropenone (1)
University Medicine Greifswald (2) · Butantan Institute (1) · Duke University (1) · Innovaderm Research Inc. (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1) · Red de Terapia Celular (1) · Sandoz (1) · University of Alberta (1) · University of California, Los Angeles (1) · University of Nebraska (1)
United States (4) · Canada (2) · Germany (2) · Brazil (1) · Spain (1)
Werner Siegmund, Prof (2) · Brian Lowes, MD (1) · Devai Desai, MD, PhD (1) · Gerald Gantt, M.D. (1) · Michael T Clandinin, PhD (1) · Ricardo Palacios, MD, PhD (1) · Robert Bissonnette, MD (1) · William H. Harmon, MD (1) · Yusaku Michael Shino, MD (1)
PMID 10028970, PMID 10030657, PMID 10199738, PMID 10213344, PMID 10556226, PMID 10594802, PMID 10598732, PMID 10802712, PMID 10830164, PMID 10952828, PMID 11055975, PMID 11057898, PMID 11250334, PMID 11514367, PMID 11803349, PMID 12088775, PMID 12555153, PMID 12652219, PMID 12668503, PMID 12714020, PMID 12738602, PMID 12742978, PMID 12906982, PMID 12962864, PMID 1423934, PMID 14612424, PMID 14757690, PMID 14996650, PMID 15226426, PMID 15239621, PMID 15302787, PMID 15543153, PMID 15557389, PMID 16199143, PMID 16297769, PMID 16297770, PMID 16297806, PMID 16364861, PMID 16611334, PMID 16642009, PMID 16795076, PMID 17060862, PMID 17258148, PMID 1729347, PMID 17314109, PMID 17396135, PMID 17450150, PMID 17479097, PMID 17845572, PMID 18025531