15 completed, 13 unknown, 10 recruiting, 4 terminated. 19 Not applicable, 1 Early Phase 1, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 19 | Recruiting 8, Unknown 5, Completed 4, Terminated 2 |
| Early Phase 1 | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Terminated 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow ICU Acquired Weakness: new trials by email Literature Review of ICU Acquired Weakness trials Research Report on ICU Acquired Weakness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Protein, Mobility Therapy and Electric Stimulation on Recovery in Older ICU Survivors MRP and High Protein Supplement (HPRO) and Neuromuscular Electric Stimulation (NMES) - Critical Illness, Sarcopenia | Early Phase 1 | Not yet recruiting | University of Maryland, Baltimore | 78 | 2027-03-01 | 2026-05-06 |
| ICU CONNECT: Study Comparing EMG in Healthy Volunteers and ICU Patients. TetraGraph, Electromyography, Nerve conduction studies - ICU Acquired Weakness | Not applicable | Recruiting | Endeavor Health | 24 | 2026-06-01 | 2026-07-13 |
| Development of an Early Warning Model for Intensive Care Unit-Acquired Weakness in Mechanically Ventilated Children ICU-AW - ICU Acquired Weakness | Enrolling by invitation | Children's Hospital of Fudan University | 1500 | 2026-03-01 | 2026-03-19 | |
| Exploring Novel Biomarkers of ICU-AW in Mechanically Ventilated Children at the Molecular Level ICU-AW - ICU Acquired Weakness | Enrolling by invitation | Children's Hospital of Fudan University | 500 | 2026-03-01 | 2026-03-19 | |
| Predictive Validity of the Chelsea Critical Care Physical Assessment Tool (CPAx) for Regaining Autonomy Three Months After ICU Discharge CPAx - ICU Acquired Weakness, Intensive Care Neuropathy | Active not recruiting | Centre Hospitalier Intercommunal Elbeuf-Louviers-Val de Reuil | 29 | 2025-09-01 | 2026-09-02 | |
| Effect of the "Sitting Out of Bed in an Arm-chair Position" in ICU on Functional Recovery Among Ventilated Patients sitting out of bed in an arm-chair position - ICU Acquired Weakness | Not applicable | Recruiting | Centre Hospitalier Régional d'Orléans | 150 | 2025-07-04 | 2025-12-19 |
| ICU-Recover Box 2.0, Smart Technology for Home Monitoring of ICU Patients The ICU-Recover Box: using smart technology for monitoring health status after ICU admission Pilot 2.0 - ICU Acquired Weakness | Not applicable | Recruiting | Leiden University Medical Center | 50 | 2025-07-01 | 2025-09-29 |
| TESTO-TRIAL: Use of Testosterone in Critically Ill Patients Testosterone cypionate (200mg/3ml), Sesame oil (3ml) - Weaning Failure, Muscle Weakness | Phase 4 | Active not recruiting | Leticia Maria Defendi Barboza Marson | 94 | 2024-09-09 | 2024-12-18 |
| Behavioral Economic & Staffing Strategies in the ICU Realtime audit and feedback, RN Implementation Facilitator - Implementation Science, Delirium | Not applicable | Recruiting | University of Nebraska | 16500 | 2024-07-01 | 2026-09-29 |
| Hand and Arm Rehabilitation Using VR VR training for arm and hand rehabilitation - Post-Intensive Care Syndrome, ICU Acquired Weakness | Not applicable | Recruiting | Frisius Medisch Centrum | 108 | 2024-01-15 | 2024-04-18 |
| ICU Combined Assessment of Cardio-Respiratory Exercise ICU Acquired Weakness, Sepsis | Recruiting | University of Manitoba | 50 | 2023-12-15 | 2026-06-15 | |
| Prone Positioning and Thoracoabdominal Binding on Lung and Muscle Protection in ARDS Patients During Spontaneous Breathing Prone Positioning, Thoracoabdominal Binding, Control - Acute Respiratory Distress Syndrome, Mechanical Ventilation Complication | Not applicable | Terminated | University of Chile | 14 | 2023-12-06 | 2026-09-28 |
| Evaluation of Diaphragmatic Function and Quadriceps Muscle Thickness in Patients Receiving High Protein Nutrition patients who will receive 2 gm protein/kg/day will be evaluated by ultrasound for diaphragmatic function and quadriceps muscle thickness - ICU Acquired Weakness | Not applicable | Unknown | Zagazig University | 32 | 2023-10-01 | 2023-09-14 |
| Safety and Efficacy of the MyokinE100 (CL-EMS Alpha) Device in Inducing Visible Muscle Contraction in Healthy Volunteers Electrical muscle stimulation - ICU Acquired Weakness | Not applicable | Completed | Health Discovery Labs | 8 | 2023-08-22 | 2023-09-26 |
| Improved Muscle Metabolism by Combination of Muscle Activation and Protein Substitution ( IMEMPRO ) Dietary Supplement: additional substitution of protein, Neuromuscular electrical stimulation, Early Mobilization - ICU Acquired Weakness, Muscle Atrophy | Not applicable | Recruiting | Technical University of Munich | 40 | 2023-06-27 | 2026-03-03 |
| Optimised Nutritional Therapy and Early Physiotherapy in Long Term ICU Patients (NutriPhyT Trial) Optimisation of nutrition therapy coupled with early mobilisation, Standard care - Critical Illness, ICU Acquired Weakness | Not applicable | Recruiting | HEIDEGGER CP | 164 | 2023-05-01 | 2025-08-12 |
| REmotely Monitored, Mobile Health Supported Multidomain Rehabilitation Program With High Intensity Interval Training for COVID-19 REmotely monitored, Mobile health supported Multidomain Rehabilitation Program with High Intensity Interval Training (REMM-HIIT) - COVID-19, Critical Illness | Not applicable | Recruiting | Duke University | 120 | 2023-02-23 | 2026-05-28 |
| 5 Years Quality of Life and Early Mobilization in ICU Questionnaires - Quality of Life, ICU Acquired Weakness | Completed | Centre Hospitalier Régional d'Orléans | 138 | 2022-10-28 | 2023-05-17 | |
| Muscle Recovery After Critical Illness ICU Acquired Weakness, Post Intensive Care Unit Syndrome | Recruiting | Esther Dupont-Versteegden | 209 | 2022-10-18 | 2026-06-26 | |
| Muscle Catabolism and Outcomes in Children Following Cardiac Surgery Muscle ultrasound to estimate lean body mass - Congenital Heart Disease, ICU Acquired Weakness | Unknown | Boston Children's Hospital | 64 | 2022-07-15 | 2023-07-19 |
Showing 20 of 47. Sign in to see all of them.
Critical Illness (11) · COVID-19 (3) · Muscle Weakness (3) · Sarcopenia (3) · postintensive care syndrome (3) · Malnutrition (2) · Muscular Atrophy (2) · Accidental Injuries (1) · Acute Lung Injury (1) · Asthenia (1) · Constipation (1) · Delirium (1) · Diarrhea (1) · Heart Defects, Congenital (1) · Liver Failure (1)
Pathological Conditions, Signs and Symptoms (16) · Pathologic Processes (12) · Disease Attributes (11) · Nervous System Diseases (11) · Signs and Symptoms (10) · Neurologic Manifestations (9) · Neuromuscular Manifestations (8) · Atrophy (5) · Infections (5) · Pathological Conditions, Anatomical (5) · Respiratory Tract Diseases (5) · Lung Diseases (4) · Musculoskeletal Diseases (4) · Coronaviridae Infections (3) · Coronavirus Infections (3)
Nerve Conduction Studies (2) · Early Ambulation (1) · Electromyography (1) · High-Intensity Interval Training (1) · Intensive Care Units (1) · Muscle Relaxation (1) · Physical Therapy Modalities (1) · Prone Position (1) · Rehabilitation (1) · Sesame Oil (1) · Standard of Care (1) · Surveys and Questionnaires (1) · testosterone 17 beta-cypionate (1)
Centre Hospitalier Régional d'Orléans (2) · Children's Hospital of Fudan University (2) · Groupe Hospitalier du Havre (2) · University Hospital, Montpellier (2) · Ain Shams University (1) · Assiut University (1) · Azienda Sanitaria-Universitaria Integrata di Udine (1) · B.P. Koirala Institute of Health Sciences (1) · Boston Children's Hospital (1) · Centre Hospitalier Intercommunal Elbeuf-Louviers-Val de Reuil (1) · Centre Hospitalier Universitaire Vaudois (1) · Centro Universitário Augusto Motta (1) · Chinese PLA General Hospital (1) · Community Health System (1) · Duke University (1)
United States (11) · France (9) · China (5) · Switzerland (3) · Brazil (2) · Canada (2) · Egypt (2) · Netherlands (2) · Taiwan (2) · Turkey (Türkiye) (2) · Australia (1) · Austria (1) · Belgium (1) · Chile (1) · Germany (1)
Asher Mendelson, MD PhD (1) · Ayman Amer, professor (1) · Claudia Heidegger, MD (1) · Cliodhna Ashe, MD (1) · Esra Pehlivan, Ass.Prof (1) · Ghada Abdelrazik, professor (1) · Hakan Parlak, MD (1) · Huan-Jui Yeh (1) · Hung-Jui Chuang, Dr (1)
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1UG3HL165740-01A1 (1), 4UH3HL165740-02 (1), K23AR079583 (1), R01AR081002 (1), R01HD107103 (1)