3 recruiting, 2 completed, 2 not yet recruiting, 1 active not recruiting. 2 Not applicable, 1 Early Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 1, Recruiting 1 |
| Early Phase 1 | 1 | Recruiting 1 |
| Phase 2 | 1 | Active not recruiting 1 |
Follow Hypoxic Ischaemic Encephalopathy (HIE): new trials by email Literature Review of Hypoxic Ischaemic Encephalopathy (HIE) trials Research Report on Hypoxic Ischaemic Encephalopathy (HIE)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Measuring Heart Health in Both Term, Preterm and Unwell Newborn Babies With an Advanced Ultrasound Method: Speckle Tracking Echocardiography Premature Baby, Pulmonary Hypertension of Newborn | Not yet recruiting | Birmingham Women's NHS Foundation Trust | 190 | 2026-09-01 | 2026-07-07 | |
| Effect of Citicoline on Neurological Severity Score and Cerebral Doppler Resistive Index in Neonatal Hypoxic Ischemic Encephalopathy Citicoline, Standard medical treatment - Hypoxic Ischaemic Encephalopathy (HIE) | Not applicable | Not yet recruiting | Khyber Girls Medical College | 86 | 2026-09-01 | 2026-08-24 |
| Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE) Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE) | Enrolling by invitation | Healing Hope International | 25 | 2026-03-01 | 2026-03-23 | |
| Genetics of Neonatal Encephalopathy and Related Disorders Neonatal Encephalopathy, Hypoxic Ischaemic Encephalopathy (HIE) | Recruiting | Boston Children's Hospital | 300 | 2026-02-04 | 2026-03-11 | |
| EFFICACY OF MELATONIN IN MANAGEMENT OF HYPOXIC ISCHEMIC ENCEPHALOPATHY (HIE) IN NEONATES Melatonin, intravenous (IV) fluids, intensive monitoring, broad-spectrum antibiotic cover - Hypoxic Ischaemic Encephalopathy (HIE) | Phase 2 | Active not recruiting | University of Child Health Sciences and Children's Hospital, Lahore | 110 | 2025-12-10 | 2025-12-26 |
| Healing Tiny Minds: Rural Recovery Through Virtual and Lived Experience Care Abecedarian Approach - Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth | Not applicable | Recruiting | University of Wisconsin, Madison | 225 | 2025-06-03 | 2026-03-27 |
| Feasibility and Safety of Intranasally Administered Breast Milk in HIE Intranasal breast milk - Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischemic Encephalopathy of Newborn | Early Phase 1 | Recruiting | Semmelweis University | 10 | 2024-11-22 | 2025-05-22 |
| An Observational Study of the NeuroBell EEG Monitor NeuroBell EEG Monitor - EEG, Neonatology | Completed | University College Cork | 17 | 2024-09-02 | 2026-04-02 | |
| BiHiVE2 Study. The Investigation and Validation of Predictive Biomarkers in Hypoxic-ischaemic Encephalopathy. Hypoxic Ischaemic Encephalopathy (HIE), Asphyxia | Completed | University College Cork | 500 | 2012-03-01 | 2018-07-06 |
Hypoxia-Ischemia, Brain (9) · Cerebral Palsy (2) · Premature Birth (2) · Seizures (2) · Asphyxia (1) · Brain Injuries (1) · Drug Resistant Epilepsy (1) · Epilepsy (1) · Hernias, Diaphragmatic, Congenital (1) · Hypoxia, Brain (1) · Nervous System Diseases (1) · Neurodevelopmental Disorders (1) · Quadriplegia (1) · Stroke (1)
Brain Diseases (9) · Brain Ischemia (9) · Cardiovascular Diseases (9) · Central Nervous System Diseases (9) · Cerebrovascular Disorders (9) · Hypoxia (9) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Signs and Symptoms, Respiratory (9) · Vascular Diseases (9) · Hypoxia, Brain (8) · Nervous System Diseases (8) · Brain Damage, Chronic (2) · Female Urogenital Diseases and Pregnancy Complications (2) · Neurologic Manifestations (2)
Cytidine Diphosphate Choline (1) · Fluid Therapy (1) · Melatonin (1)
University College Cork (2) · Birmingham Women's NHS Foundation Trust (1) · Boston Children's Hospital (1) · Healing Hope International (1) · Khyber Girls Medical College (1) · Semmelweis University (1) · University of Child Health Sciences and Children's Hospital, Lahore (1) · University of Wisconsin, Madison (1)
Ireland (2) · Pakistan (2) · United States (2) · Hungary (1) · Mexico (1) · Sweden (1) · United Kingdom (1)
Brian Walsh, MD (1) · Deirdre Murray, MD (1) · Dr. Anna Lara Kattan, MD: Regenerative Medicine (1) · Melisa Carrasco McCaul, MD, PhD (1) · Muhammad Khalid Masood, MBBS, FCPS (1) · Romisa Rehman (1) · Unoke Meder, MD, PhD (1)
PMID 23157330, PMID 23227182, PMID 23823198, PMID 23891891, PMID 23931672, PMID 25697106, PMID 26001314, PMID 26733938, PMID 27486995, PMID 27957679, PMID 28490023, PMID 28840775