13 completed, 5 unknown, 3 recruiting, 2 terminated. 6 Not applicable, 4 Phase 2, 4 Phase 3, 3 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 6 | Completed 5, Terminated 1 |
| Phase 2 | 4 | Unknown 2, Completed 1, Terminated 1 |
| Phase 3 | 4 | Withdrawn 2, Recruiting 1, Unknown 1 |
| Phase 4 | 3 | Completed 2, Recruiting 1 |
Follow Hospital-acquired Pneumonia: new trials by email Literature Review of Hospital-acquired Pneumonia trials Research Report on Hospital-acquired Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cefepime-taniborbactam vs Meropenem in Adults With VABP or Ventilated HABP Cefepime-taniborbactam, Meropenem - Ventilator-associated Pneumonia, Hospital-acquired Pneumonia | Phase 3 | Withdrawn | Venatorx Pharmaceuticals, Inc. | 2025-06-01 | 2025-06-08 | |
| Acyclovir in Ventilated Patients With Pneumonia and HSV-1 in BAL Acyclovir - Pneumonia, Viral, Ventilator Associated Pneumonia | Phase 3 | Recruiting | Jena University Hospital | 616 | 2024-02-20 | 2026-07-23 |
| A Study to Learn About the Study Medicine Zavicefta After it is Released Into the Markets in Korea Complicated Intra-abdominal Infection, Complicated Urinary Tract Infection | Recruiting | Pfizer | 600 | 2024-02-19 | 2026-09-08 | |
| EaRly impAct theraPy With Ceftazidime-avibactam Via rapID Diagnostics Rapid Diagnostics - Blood Stream Infections, Ventilator Associated Pneumonia | Phase 4 | Recruiting | National University of Singapore | 1526 | 2023-12-12 | 2026-10-22 |
| Chinese Hospital Acquired Pneumonia Collaboration Network: Epidemiology, Diagnosis and Treatment prognosis status - Hospital-acquired Pneumonia, Antibiotic Resistant Infection | Not yet recruiting | Ruijin Hospital | 4000 | 2023-10-01 | 2023-09-08 | |
| "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. Baricitinib 4 MG - Hospital-acquired Pneumonia | Phase 2 / Phase 3 | Unknown | Nantes University Hospital | 450 | 2023-07-01 | 2023-06-22 |
| Feasibility Study of Contemporary Diagnostics for Patients With Suspected Hospital-Acquired Pneumonia. CT scan, FilmArray Pneumonia Panel - Hospital-acquired Pneumonia | Not applicable | Completed | University of Liverpool | 220 | 2023-06-13 | 2025-09-05 |
| Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia Anakinra Prefilled Syringe, Placebo - Community-acquired Pneumonia, Hospital-acquired Pneumonia | Phase 2 | Completed | Hellenic Institute for the Study of Sepsis | 60 | 2023-03-06 | 2024-07-31 |
| Diagnostic Performance and Impact of a Multiplex PCR Pneumonia Panel in ICU Patients With Severe Pneumonia. Multiplex respiratory PCR - Community-acquired Pneumonia, Hospital-acquired Pneumonia | Completed | Avicenna Military Hospital | 210 | 2023-02-03 | 2024-02-23 | |
| Efficacy of Intravenous Amboxol Hydrochloride as an Adjunct Therapy for Severe Pneumonia in Critically Ill Patients Ambroxol Hydrochloride, Standard Therapy - Severe Pneumonia, Community-acquired Pneumonia | Phase 4 | Completed | National University of Malaysia | 32 | 2023-01-07 | 2023-12-27 |
| Hospital Acquired Pneumonia in Temporary Tracheostomy Tracheostomy, Overnight intubation - Head and Neck Cancer, Tracheostomy Complication | Unknown | Guy's and St Thomas' NHS Foundation Trust | 193 | 2022-06-01 | 2022-06-14 | |
| Comprehensive Molecular Diagnosis and Management of Hospital- and Ventilator-associated Pneumonia in Norway Molecular diagnostics in HAP and VAP - Pneumonia, Ventilator-Associated, Hospital-acquired Pneumonia | Unknown | Vestre Viken Hospital Trust | 550 | 2021-06-15 | 2021-12-06 | |
| Efficacy and Safety of Ceftazidime-Avibactam (CAZ-AVI) in Chinese Participants With HAP (Including VAP) Zavicefta, Ceftazidime-Avibactam - Hospital-Acquired Pneumonia | Phase 4 | Completed | Pfizer | 235 | 2021-05-21 | 2024-09-19 |
| Identifying Risk Factors for Gram-negative Resistance for HAP/VAP in the Intensive Care Unit Observational - Ventilator-associated Pneumonia, Hospital-acquired Pneumonia | Completed | Methodist Health System | 132 | 2020-06-30 | 2026-03-23 | |
| 0.12% Chlorhexidine Oral Care for the Prevention of Non-ventilator Hospital-acquired Pneumonia 0.12% Chlorhexidine Oral Liquid Product, Listerine Oral Liquid Product, Normal Saline Product - Hospital-acquired Pneumonia | Not applicable | Completed | National Cheng-Kung University Hospital | 103 | 2020-05-25 | 2021-12-14 |
| HOspital NEtwork STudy - Preparation for a Randomized Evaluation of Anti-Pneumonia Strategies Hospital-acquired Pneumonia, Ventilator Associated Pneumonia | Completed | UMC Utrecht | 2165 | 2020-05-20 | 2023-11-29 | |
| Trial on a Strategy Combining Rapid Diagnostic Testing and Antimicrobial Stewardship to Improve Antibiotic Use in Patients With Hospital-acquired Pneumonia. Rapid Diagnostic Testing, Antimicrobial stewardship - Hospital-acquired Pneumonia | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 116 | 2020-02-21 | 2026-08-12 |
| Impact of Antimicrobial Stewardship on Outcomes of Patients With Hospital-acquired Pneumonia Due to Gram-negative Bacilli - A Before-after Study No intervention - Hospital-acquired Pneumonia | Completed | Nantes University Hospital | 420 | 2019-06-01 | 2022-02-17 | |
| A Study of Meropenem-Vaborbactam Versus Piperacillin/Tazobactam in Participants With Hospital-Acquired and Ventilator-Associated Bacterial Pneumonia Meropenem-Vaborbactam, Piperacillin/Tazobactam - Hospital-Acquired Bacterial Pneumonia, Ventilator-Associated Bacterial Pneumonia | Phase 3 | Withdrawn | Melinta Therapeutics, Inc. | 2018-08-01 | 2019-01-11 | |
| Effect of Angulus on Patient-elevation Compliance Angulus - Ventilator Adverse Event, Ventilator Associated Pneumonia | Not applicable | Completed | Angulus, LLC | 90 | 2018-07-10 | 2024-03-06 |
Showing 20 of 26. Sign in to see all of them.
Healthcare-Associated Pneumonia (26) · Pneumonia, Ventilator-Associated (11) · Pneumonia (5) · Community-Acquired Pneumonia (4) · Cross Infection (3) · Communicable Diseases (1) · Critical Illness (1) · Gram-Negative Bacterial Infections (1) · Head and Neck Neoplasms (1) · Herpes Simplex (1) · Iatrogenic Disease (1) · Pneumonia, Bacterial (1) · Pneumonia, Viral (1) · Respiratory Tract Infections (1) · Sepsis (1)
Disease Attributes (26) · Infections (26) · Lung Diseases (26) · Pathologic Processes (26) · Pathological Conditions, Signs and Symptoms (26) · Respiratory Tract Diseases (26) · Iatrogenic Disease (25) · Respiratory Tract Infections (25) · Cross Infection (23) · Pneumonia (21) · Community-Acquired Infections (4) · Bacterial Infections (2) · Bacterial Infections and Mycoses (2) · DNA Virus Infections (1) · Herpesviridae Infections (1)
Vancomycin (2) · Acyclovir (1) · Ambroxol (1) · Interleukin 1 Receptor Antagonist Protein (1) · Linezolid (1) · Meropenem (1) · Piperacillin, Tazobactam Drug Combination (1) · Rapid Diagnostic Tests (1) · Standard of Care (1) · Tomography, X-Ray Computed (1) · Tracheostomy (1) · Watchful Waiting (1) · avibactam, ceftazidime drug combination (1) · baricitinib (1) · colistinmethanesulfonic acid (1)
Pfizer (3) · Methodist Health System (2) · Nantes University Hospital (2) · Angulus, LLC (1) · Arpida AG (1) · Assistance Publique - Hôpitaux de Paris (1) · Avicenna Military Hospital (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Hellenic Institute for the Study of Sepsis (1) · Jena University Hospital (1) · Melinta Therapeutics, Inc. (1) · National Cheng-Kung University Hospital (1) · National University of Malaysia (1) · National University of Singapore (1)
France (5) · United States (3) · China (2) · Malaysia (2) · South Korea (2) · Taiwan (2) · United Kingdom (2) · Albania (1) · Belgium (1) · Croatia (1) · Czechia (1) · Germany (1) · Greece (1) · India (1) · Latvia (1)
Aline Wolfensberger, MD (1) · David Paterson, Professor (1) · David Willms, MD (1) · Elling Ulvestad, MD, PhD (1) · Evangelos Giamarellos-Bourboulis, MD, PhD (1) · Harleen Grewal, MD, PhD (1) · Lars Heggelund, MD, PhD (1) · Lauren Clack, PhD (1) · Marc Bonten, MD, PhD (1) · Matt Crotty, PharmD (1) · Matthew Crotty, PharmD (1) · Michelle Gong, MD (1)
PMID 30538161, PMID 32807090, PMID 33395094, PMID 36893785, PMID 38670599, PMID 38964799, PMID 41225316, PMID 41552367, PMID 42534393
R43HL131177 (1)