20 unknown. 20 Phase 1, 7 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 20 | Unknown 20 |
| Phase 2 | 7 | Unknown 7 |
Follow Heredodegenerative Disorders, Nervous System: new trials by email Literature Review of Heredodegenerative Disorders, Nervous System trials Research Report on Heredodegenerative Disorders, Nervous System
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Toxicity and Efficacy Evaluation of Topical Minoxidil in Acne Vulgaris topical minoxidil in Acne Vulgaris - Acne Vulgaris | Phase 1 / Phase 2 | Unknown | Chang Gung Memorial Hospital | 26 | 2023-07-11 | 2023-11-03 |
| Clinical Trial to Assess the Safety and Efficacy of EXG001-307 in Patients with Spinal Muscular Atrophy Type 1 EXG001-307 injection - Spinal Muscular Atrophy Type I | Phase 1 / Phase 2 | Unknown | Guangzhou Jiayin Biotech Ltd | 12 | 2023-02-16 | 2024-09-19 |
| A Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of TQ-B3234 in Patients With Type I Neurofibromatosis TQ-B3234 capsule - Type I Neurofibromatosis | Phase 1 | Unknown | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 120 | 2021-11-01 | 2021-11-04 |
| AN0025 and Pembrolizumab Combination in Advanced Solid Tumors AN0025, Pembrolizumab - Triple-negative Breast Cancer, NSCLC, Squamous or Non-Squamous | Phase 1 | Unknown | Adlai Nortye Biopharma Co., Ltd. | 63 | 2020-08-20 | 2024-06-27 |
| Symptomatic Therapy for Patients With Huntington's Disease Haloperidol 2Mg Tab, Risperidone 1Mg Tab, Zoloft 50Mg Tablet - Huntington Disease | Phase 1 | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 60 | 2020-03-12 | 2021-04-02 |
| Metformin in Patients With Fragile X Metformin, Placebo oral tablet - Fragile X Syndrome | Phase 1 / Phase 2 | Unknown | Rowan University | 40 | 2019-10-29 | 2019-10-31 |
| Nilotinib in Huntington's Disease Nilotinib 150 MG - Huntington Disease | Phase 1 | Unknown | Georgetown University | 10 | 2018-11-15 | 2020-02-20 |
| CKD-504 in SAD and MAD in Healthy Korean and Caucasian Adult Male and Female Subjects CKD-504, Placebo - Huntington Disease | Phase 1 | Unknown | Chong Kun Dang Pharmaceutical | 88 | 2018-05-23 | 2020-02-24 |
| Safety Evaluation of Cellavita HD Administered Intravenously in Participants With Huntington's Disease Cellavita HD Lower Dose, Cellavita HD Higher dose - Huntington Disease | Phase 1 | Unknown | Azidus Brasil | 6 | 2017-10-16 | 2022-11-02 |
| Allogeneic Adipose Derived Stem Cells for Werdnig Hoffman Patients Adipose derived mesenchymal stem cell - Infantile Spinal Muscular Atrophy, Type I [Werdnig- Hoffman] | Phase 1 / Phase 2 | Unknown | Tehran University of Medical Sciences | 10 | 2015-06-01 | 2016-08-04 |
| An Open-label Trial of Intravenous Immune Globulin (IVIG)in Treating Spinocerebellar Ataxias Intravenous Immune Globulin (IVIG) - Spinocerebellar Ataxias | Phase 1 | Unknown | University of South Florida | 10 | 2015-04-01 | 2016-06-08 |
| Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy transduced CD34+ hematopoietic stem cell - Metachromatic Leukodystrophy, Adrenoleukodystrophy | Phase 1 / Phase 2 | Unknown | Shenzhen Second People's Hospital | 50 | 2015-01-01 | 2022-05-31 |
| Safety and Efficacy of Bone Marrow Derived MNCs for Treatment of Cells for the Treatment of Hunting Tons Chorea. autologous Stem Cell - Huntington Disease | Phase 1 / Phase 2 | Unknown | Chaitanya Hospital, Pune | 50 | 2014-09-01 | 2014-09-17 |
| An Open Label, Exploratory Study to Investigate the Treatment Effect of Glatiramer Acetate on Girls Woth Rett Syndrome Glatiramer Acetate (Copaxone®) - Rett Syndrome | Phase 1 | Unknown | Sheba Medical Center | 10 | 2014-01-01 | 2014-02-04 |
| Safety and Tolerability Study of RAD001 and LBH589 in All Solid Tumors With Enrichment for EBV Driven Tumors LBH589 and RAD001 - Nasopharyngeal Carcinoma, Lymphomas, Any EBV+ Solid Tumour | Phase 1 | Unknown | National Cancer Centre, Singapore | 49 | 2010-03-01 | 2018-04-24 |
| Safety and Efficacy of Umbilical Cord Mesenchymal Stem Cell Therapy for Patients With Hereditary Ataxia human umbilical cord mesenchymal stem cells - Hereditary Ataxia | Phase 1 / Phase 2 | Unknown | Shenzhen Beike Bio-Technology Co., Ltd. | 20 | 2010-01-01 | 2012-11-28 |
| Far Infrared Irradiation for Managing, Control and Treatment of Huntington's Disease (HD) Far Infrared Radiation - Huntington Disease | Phase 1 | Unknown | GAAD Medical Research Institute Inc. | 5 | 2008-05-01 | 2009-01-05 |
| The Efficacy of Using Far Infrared Radiation to Manage Muscular Dystrophies Far Infrared Radiation - Muscular Dystrophies | Phase 1 | Unknown | GAAD Medical Research Institute Inc. | 4 | 2008-05-01 | 2009-08-17 |
| Ursodiol in Huntington's Disease ursodiol, placebo - Huntington Disease | Phase 1 | Unknown | Oregon Health and Science University | 21 | 2007-08-01 | 2009-02-05 |
| GTA-Glyceryltriacetate for Canavan Disease GTA: Glyceryltriacetate - Infantile Canavan Disease, Deficiency Disease, Aspartoacylase | Phase 1 | Unknown | Sheba Medical Center | 5 | 2006-01-01 | 2006-08-15 |
Huntington Disease (7) · Chorea (2) · Spinal Muscular Atrophies of Childhood (2) · Spinocerebellar Degenerations (2) · Acne Vulgaris (1) · Adrenoleukodystrophy (1) · Bulbo-Spinal Atrophy, X-Linked (1) · Canavan Disease (1) · Carcinoma, Non-Small-Cell Lung (1) · Colorectal Neoplasms (1) · Distal Myopathies (1) · Fragile X Syndrome (1) · Glycogen Storage Disease Type V (1) · Hereditary Sensory and Autonomic Neuropathies (1) · Leukodystrophy, Metachromatic (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (20) · Genetic Diseases, Inborn (20) · Nervous System Diseases (20) · Neurodegenerative Diseases (17) · Central Nervous System Diseases (15) · Brain Diseases (12) · Dyskinesias (8) · Basal Ganglia Diseases (7) · Cognition Disorders (7) · Dementia (7) · Mental Disorders (7) · Movement Disorders (7) · Neurocognitive Disorders (7) · Neurologic Manifestations (6)
Cell- and Tissue-Based Therapy (2) · CKD-504 (1) · E7046 (1) · Everolimus (1) · Glatiramer Acetate (1) · Haloperidol (1) · Histone Deacetylase Inhibitors (1) · Immunoglobulins, Intravenous (1) · Metformin (1) · Minoxidil (1) · Panobinostat (1) · Risperidone (1) · Sertraline (1) · Tablets (1) · Ursodeoxycholic Acid (1)
GAAD Medical Research Institute Inc. (2) · Sheba Medical Center (2) · Adlai Nortye Biopharma Co., Ltd. (1) · Azidus Brasil (1) · Chaitanya Hospital, Pune (1) · Chang Gung Memorial Hospital (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Chong Kun Dang Pharmaceutical (1) · Georgetown University (1) · Guangzhou Jiayin Biotech Ltd (1) · National Cancer Centre, Singapore (1) · Oregon Health and Science University (1) · Rowan University (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · Shenzhen Beike Bio-Technology Co., Ltd. (1)
China (5) · United States (5) · Canada (2) · Israel (2) · Brazil (1) · France (1) · India (1) · Iran (1) · Singapore (1) · South Korea (1) · Taiwan (1)
Ken Nedd, M.D. (2) · Amir Ali Hamidieh, MD (1) · Andreea Nissenkorn, Dr. (1) · Bruria Ben Zeev, prof. (1) · Cheng-Lung Hsu, Profesor (1) · Daniel Tan Shao Weng (1) · GuangFu Chen, M.D.,Ph.D (1) · Hua Jiang, M.D,Ph.D (1) · Irit Avisar, R.N M.A (1) · Jiacai Zhuo (1) · Joyce Macedo da Silva, MD (1) · Kyung-Sang Yu (1) · Mahmoode Reza Ashrafi, MD (1) · Penelope Hogarth, M.D. (1)
PMID 11231629, PMID 11399225, PMID 19892975, PMID 23151076, PMID 23845948, PMID 23966770, PMID 27434297, PMID 40458203, PMID 41188963
2019 (1)