E7046: Clinical Trials

4 trials of E7046, newest first

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2 completed, 1 terminated, 1 unknown. 4 Phase 1.

By phase and status

PhaseTrialsStatus
Phase 14Completed 2, Terminated 1, Unknown 1

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Trials newest first · largest first

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Double/Triple Combinations of AN2025, AN0025 and Atezolizumab in Advanced Solid Tumors
AN2025, AN0025, Atezolizumab 1200 mg in 20 ML Injection - Locally Advanced Solid Tumor
Phase 1CompletedAdlai Nortye Biopharma Co., Ltd.472021-09-072025-06-22
AN0025 and Pembrolizumab Combination in Advanced Solid Tumors
AN0025, Pembrolizumab - Triple-negative Breast Cancer, NSCLC, Squamous or Non-Squamous
Phase 1UnknownAdlai Nortye Biopharma Co., Ltd.632020-08-202024-06-27
Preoperative Radiotherapy and E7046 in Rectum Cancer
E7046, Long Course Chemoradiotherapy (LCRT), Short Course Radiotherapy (SCRT) - Neoadjuvant Therapy in Rectal Cancer
Phase 1CompletedAdlai Nortye Biopharma Co., Ltd.292017-05-172021-10-04
Study of E7046 in Subjects With Selected Advanced Malignancies
E7046 - Tumors
Phase 1TerminatedEisai Inc.312015-07-302020-02-17

Conditions studied

Carcinoma, Non-Small-Cell Lung (1)  ·  Colorectal Neoplasms (1)  ·  Neoplasms (1)  ·  Rectal Neoplasms (1)  ·  Spinocerebellar Degenerations (1)  ·  Triple Negative Breast Neoplasms (1)  ·  Uterine Cervical Neoplasms (1)

Sponsors

Adlai Nortye Biopharma Co., Ltd. (3)  ·  Eisai Inc. (1)

Countries

United States (4)  ·  France (2)  ·  Poland (1)  ·  United Kingdom (1)

Top investigators

Robert Atkinson, Ph.D. (1)  ·  Robert Atkinson, PhD, MSCR (1)

Results publications

PMID 32554609

NIH funding

2014 (1), 2016 (1), 2019 (1)