1148 completed, 356 unknown, 150 terminated, 100 recruiting. 457 Phase 2, 347 Phase 4, 304 Phase 3, 270 Phase 1, 159 Not applicable.
Follow Hepatitis, Chronic: new trials by email Literature Review of Hepatitis, Chronic trials Research Report on Hepatitis, Chronic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D Hepalatide 2.1mg, Placebo of Hepalatide - Hepatitis D, Chronic | Phase 3 | Not yet recruiting | Shanghai HEP Pharmaceutical Co., Ltd. | 150 | 2027-06-01 | 2026-10-28 |
| B-Ensure: Long-term Follow-up Study to Evaluate Durability of Treatment Response in Previous Bepirovirsen Study Participants Bepirovirsen - Hepatitis B | Phase 4 | Not yet recruiting | GlaxoSmithKline | 303 | 2026-12-03 | 2026-11-02 |
| Targeting ANKRD11 Reverses HBV-Specific CD8+ T Cell Dysfunction and Tolerance Chronic Hepatitis B | Not yet recruiting | Beijing Municipal Administration of Hospitals | 40 | 2026-12-01 | 2026-08-28 | |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, Placebo, TVAX-008 - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 105 | 2026-10-31 | 2026-10-19 |
| A Study of Sequential Therapy With AHB-137 Injection Followed by TVAX-008 Injection in Participants Living With Chronic Hepatitis B (CHB) AHB-137, TVAX-008, Placebo - Chronic Hepatitis B | Phase 1 / Phase 2 | Not yet recruiting | Grand Theravac Life Sciences (Hangzhou) Co., Ltd. | 105 | 2026-10-31 | 2026-10-27 |
| Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Characteristics of ACT500 in Participants With Metabolic Dysfunction-Associated Steatotic Liver Disease Complicated With Chronic Hepatitis B ACT500 Tablets, ACT500 Placebo Tablets - Metabolic Dysfunction-associated Steatotic Liver Disease, Chronic Hepatitis b | Phase 1 | Not yet recruiting | Xiamen Amoytop Biotech Co., Ltd. | 24 | 2026-10-30 | 2026-09-14 |
| A Clinical Study of AHB-121 in Healthy Participants and Chronic Hepatitis B (CHB) Participants AHB-121, Placebo - Chronic Hepatitis B Virus | Phase 1 | Not yet recruiting | Ausper Biopharma Co., Ltd. | 110 | 2026-10-28 | 2026-10-21 |
| A Trial of Inebilizumab in Participants With Autoimmune Hepatitis Inebilizumab, Placebo, Standard of Care - Autoimmune Hepatitis, AIH | Phase 3 | Recruiting | Amgen | 180 | 2026-10-13 | 2026-10-16 |
| Wearable Patch Ultrasound Probe for Diagnosis of Liver Stiffness Wearable Patch-Type Ultrasound Probe, Transient Elastography (FibroScan) - Liver Fibrosis, Liver Cirrhosis | Not yet recruiting | Second Affiliated Hospital of Xi'an Jiaotong University | 150 | 2026-10-01 | 2026-07-21 | |
| Phase Ia/Ib Trial of SCTA02A Injection in Healthy Adults and Patients With Chronic Hepatitis B SCTA02A, Placebo - Hepatitis B | Phase 1 | Not yet recruiting | Sinocelltech Ltd. | 60 | 2026-10-01 | 2026-10-29 |
| Thyroid Disorders in Pediatric Autoimmune Hepatitis Thyroid Disease, Autoimmune Hepatitis | Not yet recruiting | Assiut University | 32 | 2026-09-15 | 2026-09-22 | |
| Prospective Evaluation of Hepatocellular Carcinoma Surveillance in At-Risk Patients (Screening HCC) Hepatocellular Carcinoma, Liver Cirrhosis | Not yet recruiting | D'Or Institute for Research and Education | 300 | 2026-09-15 | 2026-08-14 | |
| A Trial to Evaluate the Efficacy and Safety of WGc0201 in Patients With Chronic Hepatitis B Virus Infection WGc0201 - Chronic Hepatitis B Virus (Hbv) | Phase 1 | Recruiting | Jiyan Liu | 9 | 2026-09-01 | 2026-07-01 |
| Hepatitis B Infection Surveillance Chronic Hepatitis B Infection | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 1360 | 2026-09-01 | 2026-07-27 | |
| Clinical Trial of TQA3605 Tablet in Combination With Nucleos(t)Ide Analogues(NAs) Versus NAs Alone for the Treatment of Patients With Chronic Hepatitis B Virus Infection Who Have Undergone Treatment and Exhibit Low Viral Load or Poor Response TQA3605 tablets Placebo, TQA3605 tablets, Entecavir dispersible tablets - Chronic Hepatitis B | Phase 3 | Not yet recruiting | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 930 | 2026-09-01 | 2026-10-02 |
| Sequential PD-1 Antibody and Pegylated Interferon Therapy for Nucleos(t)Ide Analogue-suppressed Chronic Hepatitis B Sintilimab, Pegylated Interferon-α 2b, Nucleos(t)ide Analogues - Chronic Hepatitis B | Not applicable | Not yet recruiting | Beijing 302 Hospital | 60 | 2026-09-01 | 2026-09-09 |
| Study of AHB-137 in Chronic Hepatitis B (CHB) Participants in North America and Europe Regions AHB-137 - Hepatitis B, Chronic | Phase 2 | Recruiting | AusperBio Therapeutics Inc. | 70 | 2026-09-01 | 2026-10-29 |
| HCC Risk Prediction Model Based on Multimodal Data in Chronic Hepatitis B No intervention (observational study) - Hepatocellular Carcinoma (HCC) | Not yet recruiting | Beijing Friendship Hospital | 2000 | 2026-08-20 | 2026-08-28 | |
| A Study on the Consistency Evaluation of Digital PCR Technology for Quantitative Detection of HBV Nucleic Acid the results were classified according to concentration levels - Chronic Hepatitis b | Not yet recruiting | Beijing Municipal Administration of Hospitals | 200 | 2026-08-01 | 2026-07-07 | |
| Study of GST-HG131&141 Tablets Compared With Placebo in Patients With Chronic Hepatitis B GST-HG141, GST-HG131, GST-HG141 Placebo - Chronic Hepatitis B | Phase 2 | Recruiting | Fujian Akeylink Biotechnology Co., Ltd. | 80 | 2026-07-10 | 2026-07-17 |
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Ribavirin (411) · peginterferon alfa-2a (300) · entecavir (141) · peginterferon alfa-2b (131) · Tenofovir (116) · Sofosbuvir (60) · tenofovir alafenamide (46) · ombitasvir (45) · Lamivudine (43) · Telbivudine (42) · adefovir dipivoxil (41) · paritaprevir (41) · dasabuvir (38) · daclatasvir (36) · Ritonavir (33)
Hoffmann-La Roche (132) · Merck Sharp & Dohme LLC (110) · AbbVie (72) · Gilead Sciences (71) · Bristol-Myers Squibb (42) · GlaxoSmithKline (37) · Third Affiliated Hospital, Sun Yat-Sen University (34) · Beijing Ditan Hospital (31) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (28) · National Taiwan University Hospital (25) · Nanfang Hospital, Southern Medical University (21) · Boehringer Ingelheim (18) · Assembly Biosciences (17) · Novartis Pharmaceuticals (17) · ANRS, Emerging Infectious Diseases (15)
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Chen-Hua Liu, MD (10) · Junqi Niu (7) · Marc G Ghany, M.D. (7) · Ralph T. Doyle (7)
PMID 30739368, PMID 30977945, PMID 30012435, PMID 30923816, PMID 31568620, PMID 30529905, PMID 28427875, PMID 29377566, PMID 30868245, PMID 41586499, PMID 19052126, PMID 28193518, PMID 23607593, PMID 23607594, PMID 24329937, PMID 24915612, PMID 25040192, PMID 25348661, PMID 25987775, PMID 26947564, PMID 27553375, PMID 27658343, PMID 28404091, PMID 28404092, PMID 29404492, PMID 29405329, PMID 29461687, PMID 30664876, PMID 35174470, PMID 35599306, PMID 37096802, PMID 12823087, PMID 15470215, PMID 16391218, PMID 16525137, PMID 18094378, PMID 19187608, PMID 20049753, PMID 20091678, PMID 20189674, PMID 20955704, PMID 21182232, PMID 22045673, PMID 22436845, PMID 22626609, PMID 23046671, PMID 23234725, PMID 23300053, PMID 23364953, PMID 23518903
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