60 completed, 3 unknown, 2 not yet recruiting, 2 terminated. 28 Phase 3, 18 Phase 4, 9 Phase 2, 8 Phase 1, 5 Not applicable.
Follow Engerix-B: new trials by email Literature Review of Engerix-B trials Research Report on Engerix-B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomised Controlled Phase 1 Study of Vaccine Therapy for Control or Cure of Chronic Hepatitis B Virus Infection Therapeutic hepatitis B vaccine, Commercial Hepatitis B vaccine - Chronic Hepatitis b | Phase 1 / Phase 2 | Not yet recruiting | Vaxine Pty Ltd | 40 | 2026-03-01 | 2025-09-22 |
| Immunogenicity and Safety Following In-House Recombinant Hepatitis B Vaccine in Indonesian Population (Phase III) In-House Recombinant Hepatitis B (Bio Farma) vaccine, Registered Hepatitis B vaccine recombinant (Engerix-B) - Vaccine Reaction, Vaccine Adverse Reaction | Phase 3 | Not yet recruiting | PT Bio Farma | 540 | 2025-09-01 | 2025-06-06 |
| The COMBAT HBV Feasibility Trial Tenofovir Disoproxil Fumarate 300 MG, Hepatitis B monovalent vaccine, Placebo - Hepatitis B, Vertical Transmission of Infectious Disease | Phase 4 | Completed | University of North Carolina, Chapel Hill | 317 | 2023-08-17 | 2026-02-19 |
| A Study on the Safety and Immune Response of AS37 Together With Hepatitis B Antigen in Adults Aged 18-45 Years GSK's Hepatitis B vaccine adjuvanted with aluminum hydroxide, GSK's HBsAg candidate vaccine adjuvanted with GSK's AS03 adjuvant system, GSK's Hepatitis B vaccine adjuvanted with GSK's AS04 adjuvant system - Hepatitis B | Phase 1 | Completed | GlaxoSmithKline | 122 | 2022-10-04 | 2026-01-15 |
| The Immune Responses After Hepatitis B Revaccination Doses in a Young Cohort recombinant hepatitis B vaccine - Hepatitis B, Vaccination; Infection | Not applicable | Recruiting | National Taiwan University Hospital | 240 | 2021-08-01 | 2026-10-21 |
| Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCD Engerix-B - Sickle Cell Disease | Not applicable | Unknown | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 30 | 2021-06-08 | 2023-06-08 |
| B-Enhancement of HBV Vaccination in Persons Living With HIV (BEe-HIVe): Evaluation of HEPLISAV-B HEPLISAV-B, ENGERIX-B - HIV Infection, Hepatitis B | Phase 3 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 638 | 2020-12-14 | 2025-07-20 |
| Study of a Pneumococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Toddlers and Infants Pneumococcal Conjugate Vaccine formulation 1, Pneumococcal Conjugate Vaccine formulation 2, Pneumococcal Conjugate Vaccine formulation 3 - Pneumococcal Immunisation, Diphtheria Immunisation | Phase 2 | Completed | Sanofi Pasteur, a Sanofi Company | 852 | 2020-05-22 | 2025-09-08 |
| Demonstration Project on Health Care Worker Protection Against Hepatitis B in Kalulushi District Engerix-B - Hepatitis B Virus, Health Care Associated Infection | Phase 4 | Completed | Centre for Infectious Disease Research in Zambia | 641 | 2019-11-25 | 2026-08-10 |
| Safety and Immunogenicity of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the Russian Federation and Mexico Meningococcal Polysaccharide (Serogroups A, C, Y, and W) Tetanus Toxoid Conjugate Vaccine, Meningococcal (Groups A, C, Y and W 135) Oligosaccharide Diphtheria CRM197 Conjugate Vaccine, Measles, Mumps, and Rubella Virus Vaccine Live - Healthy Volunteers (Meningococcal Infection) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 525 | 2018-10-17 | 2023-10-19 |
| Arresting Vertical Transmission of Hepatitis B Virus Tenofovir Disoproxil Fumarate, Monovalent HBV vaccine - Hepatitis B, Vertical Transmission of Infectious Disease | Phase 4 | Completed | University of North Carolina, Chapel Hill | 179 | 2018-09-24 | 2021-02-24 |
| Non Inferiority Trial of Locally Manufactured 'Hepa-B' Vaccine in Bangladesh. Hepa-B, Engerix B - Hepatitis B Infection | Phase 2 / Phase 3 | Completed | International Centre for Diarrhoeal Disease Research, Bangladesh | 158 | 2018-07-29 | 2022-02-11 |
| Immunogenicity and Safety of a Quadrivalent Meningococcal Conjugate Vaccine When Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers in the US MenACYW conjugate vaccine, MenACYW-135 conjugate vaccine, DTaP-IPV//Hib vaccine - Healthy Volunteers (Meningococcal Infection) | Phase 3 | Completed | Sanofi Pasteur, a Sanofi Company | 2627 | 2018-04-25 | 2024-10-15 |
| Hepatitis B Virus Vaccination in HIV-positive Patients and Individuals at High Risk for HIV Infection Engerix-B - Viral Hepatitis B, Immunization; Infection | Phase 4 | Unknown | National Taiwan University Hospital | 575 | 2017-09-06 | 2020-05-22 |
| HBsAb Response After HBV Vaccination in Chronic Hepatitis B Patients Who Have Lost HBsAg Commercial Hepatitis B vaccine, Standard Treatment - Chronic Hepatitis B, HBsAg, Hepatitis B Vaccine | Phase 3 | Unknown | Mahidol University | 97 | 2017-03-30 | 2018-01-23 |
| Safety and Immunogenicity of Pfs25M-EPA/AS01 and Pfs230D1M-EPA/AS01 Vaccines, Transmission Blocking Vaccines Against Plasmodium Falciparum, at Full and Fractional Dosing in Adults in Mali Pfs25M-EPA, Pfs230D1M-EPA, AS01 - Malaria | Phase 1 | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 301 | 2016-10-21 | 2024-12-10 |
| Long-term Persistence of Immunity to Hepatitis B in Adults Vaccinated With GlaxoSmithKline (GSK) Biologicals' Hepatitis B Vaccine (HBV), Engerix-B Engerix-B - Hepatitis B Vaccine | Phase 4 | Completed | GlaxoSmithKline | 106 | 2016-10-11 | 2020-01-02 |
| A Prospective Study of HBV Immunity and HBV Vaccination in Patients With NAFLD in Canada Engerix-B - Non-Alcoholic Fatty Liver Disease, Hepatitis B | Completed | University of Calgary | 82 | 2016-08-01 | 2021-11-03 | |
| A Pilot Study Comparing the Immunogenicity of Fendrix vs. Double-dose Engerix B in HIV-infected Non-responders to Standard Hepatitis B Vaccination Courses Engerix B, Fendrix - HIV, Communicable Diseases | Phase 2 / Phase 3 | Completed | Sheffield Teaching Hospitals NHS Foundation Trust | 13 | 2015-07-23 | 2022-09-29 |
| Efficacy of HBV Vaccine in Consolidation of Nucleos(t)Ide Analogues Therapy Engerix-B, Tenofovir, Entecavir - Chronic Hepatitis B | Phase 4 | Completed | Chang Gung Memorial Hospital | 116 | 2015-05-01 | 2019-07-30 |
Showing 20 of 68. Sign in to see all of them.
Hepatitis B (46) · Hepatitis (6) · Hepatitis A (6) · HIV Infections (5) · Kidney Failure, Chronic (5) · Haemophilus Infections (4) · Hepatitis B, Chronic (4) · Malaria (4) · Papillomavirus Infections (4) · Renal Insufficiency, Chronic (4) · Meningococcal Infections (3) · Uterine Cervical Neoplasms (3) · Diphtheria (2) · Infections (2) · Malaria, Falciparum (2)
GlaxoSmithKline (20) · Dynavax Technologies Corporation (7) · Sanofi Pasteur, a Sanofi Company (5) · University of North Carolina, Chapel Hill (4) · National Taiwan University Hospital (3) · Chang Gung Memorial Hospital (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2) · VBI Vaccines Inc. (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Centre for Infectious Disease Research in Zambia (1) · Chinese University of Hong Kong (1) · Crucell Holland BV (1) · Emergent BioSolutions (1) · HIV Vaccine Trials Network (1) · Hui Zhuang (1)
United States (14) · Belgium (9) · Canada (8) · Germany (5) · Taiwan (5) · Czechia (3) · South Africa (3) · Spain (3) · United Kingdom (3) · Australia (2) · Brazil (2) · China (2) · Democratic Republic of the Congo (2) · Malawi (2) · Malaysia (2)
Ana Puga, MD (1) · Barbara Moscicki, MD (1) · Bernard Duval, MD (1) · Carla Coffin (1) · Carleen Townsend-Akpan, CPNP (1) · Chao-Wei Hsu (1) · Chau-Ting Yeh (1) · Chien-Ching Hung, MD, PhD (1) · Christine H Lee, MD (1)
PMID 41276263, PMID 21366801, PMID 30850240, PMID 32710245, PMID 10618544, PMID 15750456, PMID 17980513, PMID 18233994, PMID 19683086, PMID 20630640, PMID 20949113, PMID 21241735, PMID 21350366, PMID 21552183, PMID 22789511, PMID 23206974, PMID 23297680, PMID 23727002, PMID 23727422, PMID 24173029, PMID 25401780, PMID 25593103, PMID 27753794, PMID 28855902, PMID 29055031, PMID 29201750, PMID 29289383, PMID 29432383, PMID 29845626, PMID 30088198, PMID 31431412, PMID 31736068, PMID 31829767, PMID 31999736, PMID 32161969, PMID 32574384, PMID 32677968, PMID 33119068, PMID 33177181, PMID 33493551, PMID 33639181, PMID 34097688, PMID 34116873, PMID 34416175, PMID 34424307, PMID 34561142, PMID 35367070, PMID 35649600, PMID 37017075, PMID 37085451
2015 (2), 2009 (1), 2018 (1), R01DA017476 (1)