15 completed, 15 terminated, 1 unknown. 11 Phase 4, 9 Phase 3, 6 Phase 2, 2 Not applicable, 2 Phase 1.
Follow clevudine: new trials by email Literature Review of clevudine trials Research Report on clevudine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Proof of Concept Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Mild and Moderate COVID-19 Clevudine, Placebo - COVID-19 | Phase 2 | Completed | Bukwang Pharmaceutical | 104 | 2021-03-19 | 2022-07-22 |
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases Computed Tomography, 18F-FMAU, Multiparametric Magnetic Resonance Imaging - Anatomic Stage IV Breast Cancer AJCC v8, Clinical Stage IV Cutaneous Melanoma AJCC v8 | Early Phase 1 | Completed | University of Southern California | 10 | 2021-02-15 | 2024-05-24 |
| The Phase 2 Study to Evaluate the Safety and Efficacy of Clevudine in Patients With Moderate COVID-19 Clevudine, Placebo - COVID-19 | Phase 2 | Completed | Bukwang Pharmaceutical | 64 | 2020-05-26 | 2022-07-22 |
| 18F-FMAU PET/CT in Diagnosing and Characterizing Prostate Cancer CAT, 18F-FMAU, Laboratory Biomarker Analysis - Prostate Neoplasm | Phase 1 | Terminated | University of Southern California | 18 | 2016-09-12 | 2023-09-07 |
| 18F-FMAU PET/CT in Imaging Patients With Advanced Cancers fluorine F 18 d-FMAU, positron emission tomography, computed tomography - Malignant Neoplasm | Not applicable | Terminated | University of Southern California | 3 | 2014-01-31 | 2024-05-24 |
| Cabozantinib-S-Malate in Treating Patients With Hormone-Resistant Metastatic Prostate Cancer cabozantinib-s-malate, fluorine F 18 d-FMAU, positron emission tomography - Adenocarcinoma of the Prostate, Hormone-resistant Prostate Cancer | Not applicable | Completed | Barbara Ann Karmanos Cancer Institute | 20 | 2013-03-01 | 2021-08-05 |
| A Clinical Trial to Investigate the Pharmacokinetic Drug-drug Interaction of Clevudine and Adefovir Dipivoxil After Oral Administration in Healthy Male Subjects Clevudine, Adefovir dipivoxil , Clevudine+Adefovir dipivoxil, Clevudine; Adefovir dipivoxil ,Clevudine +Adefovir dipivoxil, Clevudine,Adefovir dipivoxil ,Clevudine +Adefovir dipivoxil - Healthy | Phase 1 | Completed | Bukwang Pharmaceutical | 42 | 2012-04-01 | 2012-09-18 |
| A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Proportion to Roadmap Concept in Patients With HBV Associated-HCC clevudine, Adefovir - Hepatitis B Associated Hepatocellular Carcinoma | Phase 4 | Completed | Bukwang Pharmaceutical | 33 | 2010-06-01 | 2014-12-18 |
| An Open Study to Evaluate the Efficacy, Safety of Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B Clevudine 30mg, Clevudine 20mg+Adefovir dipivoxil 10mg, Clevudine 20mg - Chronic Hepatitis B | Phase 4 | Completed | Bukwang Pharmaceutical | 60 | 2010-03-01 | 2014-12-18 |
| An Study of Efficacy and Safety of Clevudine Clevudine, Adefovir - Chronic Hepatitis B | Phase 3 | Completed | Eisai Co., Ltd. | 288 | 2010-02-01 | 2013-05-14 |
| A Study to Evaluate the Efficacy and the Change of sAg Levels in Chronic Hepatitis B Patients Receiving Clevudine Treatment Over the Long Period Clevudine - Chronic Hepatitis B | Phase 4 | Terminated | Bukwang Pharmaceutical | 200 | 2009-11-01 | 2015-07-22 |
| A Study With Clevudine Monotherapy or Adefovir and Clevudine Combination in Patients With Chronic Hepatitis B Clevudine, Adefovir - Chronic Hepatitis B | Phase 4 | Terminated | Bukwang Pharmaceutical | 200 | 2009-09-01 | 2014-12-18 |
| A Study to Compare and Evaluate Intrahepatic cccDNA Reduction After Administrating Clevudine or Entecavir in the Chronic HBV Patients Clevudine, Entecavir - Chronic Hepatitis B | Phase 4 | Terminated | Bukwang Pharmaceutical | 75 | 2009-08-01 | 2014-12-18 |
| ANRS HB 05 Multicenter Study Evaluating Efficacy and Safety of Clevudine Monotherapy Versus Tenofovir Monotherapy Versus Combination Therapy of Clevudine and Tenofovir for 96 Weeks in HBeAg Negative Patients With Chronic Hepatitis B, naïve to Anti-VHB Therapy CLEVUDINE + TENOFOVIR PLACEBO, CLEVUDINE IN ASSOCIATION TENOFOVIR, TENOFOVIR + CLEVUDINE PLACEBO - HBe Negative Chronic Hepatitis B, Hepatitis B Viral Infection | Phase 3 | Terminated | French National Agency for Research on AIDS and Viral Hepatitis | 150 | 2008-12-14 | 2026-04-06 |
| Efficacy of Clevudine Plus Lamivudine for Lamivudine-resistant Chronic Hepatitis B Patients adefovir, clevudine, lamivudine - Chronic Hepatitis B | Phase 4 | Terminated | Inje University | 30 | 2008-12-01 | 2011-06-23 |
| A Study to Evaluate the Efficacy and Safety of Clevudine and Peg-interferon in Sequence Compared With Clevudine Alone in the Patients With HBeAg(+) Chronic Hepatitis B or Clevudine and Peg-interferon Sequential Treatment in Patients With Chronic Hepatitis B Who Have HBeAg(+) Clevudine, Clevudine + Peg-interferon - HBeAg(+) Chronic Hepatitis B | Phase 4 | Completed | Bukwang Pharmaceutical | 60 | 2008-12-01 | 2014-12-18 |
| A Double-Blind Randomized Clinical Trial Comparing the Safety and Antiviral Activity of 48-week Clevudine and Adefovir Dipivoxil in HBeAg(-) Chronic Hepatitis B With Compensated Liver Function Clevudine, Adefovir dipivoxil - HBeAg(-) Chronic Hepatitis B With Compensated Liver Function | Phase 4 | Completed | Bukwang Pharmaceutical | 43 | 2008-02-01 | 2012-04-25 |
| A Pilot Study to Evaluate the Safety and Efficacy of Clevudine or Adefovir Patients With LC-B Clevudine, Adefovir dipivoxil - Patients With LC-B | Phase 3 | Completed | Bukwang Pharmaceutical | 102 | 2007-12-01 | 2014-12-18 |
| Switching Study From Lamivudine to Clevudine in the Chronic Hepatitis B Patients Clevudine - Chronic Hepatitis B | Phase 4 | Completed | Bukwang Pharmaceutical | 100 | 2007-11-01 | 2012-07-26 |
| Efficacy and Safety of Clevudine Compared With Adefovir in Patients With HBeAg Positive Chronic Hepatitis Due to Hepatitis B Virus Clevudine, Adefovir - Chronic Hepatitis, Hepatitis B | Phase 3 | Terminated | Pharmasset | 2007-08-01 | 2009-04-27 |
Showing 20 of 31. Sign in to see all of them.
Hepatitis B (12) · Hepatitis B, Chronic (9) · COVID-19 (2) · Hepatitis, Chronic (2) · Prostatic Neoplasms (2) · Brain Neoplasms (1) · Breast Neoplasms (1) · Carcinoma, Renal Cell (1) · Colonic Neoplasms (1) · Glioma (1) · Hepatitis (1) · Lung Neoplasms (1) · Melanoma (1) · Neoplasms (1)
Bukwang Pharmaceutical (21) · University of Southern California (3) · Pharmasset (2) · Barbara Ann Karmanos Cancer Institute (1) · Eisai Co., Ltd. (1) · French National Agency for Research on AIDS and Viral Hepatitis (1) · Inje University (1) · Triangle Pharmaceuticals (1)
South Korea (21) · United States (7) · China (4) · Canada (3) · Argentina (2) · Australia (2) · France (2) · Greece (2) · Puerto Rico (2) · Spain (2) · Taiwan (2) · Thailand (2) · United Kingdom (2) · Brazil (1) · Hong Kong (1)
Hyo Suk Lee, M.D., Ph.D. (3) · Hyo-Suk Lee, MD. PhD (3) · Hossein Jadvar, MD (2) · George KK Lau, M.D. (1) · Guoping Yang (1) · Heon Young Lee, MD. PhD. (1) · Hyeon Woong Yang, MD. PhD. (1) · June Sung Lee, M.D. (1) · Lee Chang Don, MD, PhD (1) · M Michelle Berrey, MD, MPH (1) · M. Michelle Berrey, MD, MPH (1) · Nancy Leung, M.D. (1) · Peter Conti, MD (1) · Ulka Vaishampayan (1)
P30CA014089 (3), 2008 (1), R21EB017568 (1)