2 not yet recruiting, 2 unknown, 1 active not recruiting, 1 completed. 8 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 8 | Not yet recruiting 2, Unknown 2, Active not recruiting 1, Completed 1, Recruiting 1, Withdrawn 1 |
Follow Hepatitis B: new trials by email Literature Review of Hepatitis B trials Research Report on Hepatitis B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Pegylated Interferon Alpha-2β in Patients With Hepatitis B-related Hepatocellular Carcinoma After Radical Resection Peginterferon alfa-2b, TDF, TAF - Hepatocellular Carcinoma, HEPATITIS B CHRONIC | Early Phase 1 | Not yet recruiting | Ningbo No.2 Hospital | 156 | 2026-03-31 | 2026-04-28 |
| An Exploratory Clinical Study Evaluating EPI-003 Injection for the Treatment of Chronic Hepatitis B EPI-003 - Chronic Hepatitis B | Early Phase 1 | Not yet recruiting | Epigenic Therapeutics, Inc | 20 | 2024-12-20 | 2024-12-24 |
| Study to Evaluate Immunogenicity and Safety of TVAX-008 Injection in Non/Treated Chronic Hepatitis B Patients With HBsAg≤20IU/ml or HBsAg Negative Without Serological Conversion TVAX-008 - Chronic Hepatitis B | Early Phase 1 | Active not recruiting | Grand Theravac Life Sciences (Nanjing) Co., Ltd. | 20 | 2024-01-18 | 2025-10-02 |
| Efficacy of NA Combined With PEG-IFN-α2b in the Continuous Versus Pulsed Treatment of Patients With Chronic Hepatitis B PEGylated recombinant human interferon alpha-2b injection - Hepatitis B, Chronic | Early Phase 1 | Recruiting | Anhui Medical University | 1084 | 2023-07-01 | 2023-06-28 |
| The Efficacy and Safety of Rifaximin Treatment Rifaximin 200 mg, Standard Treatment without Rifaximin - Liver Failure, Acute on Chronic, Hepatic Encephalopathy | Early Phase 1 | Unknown | Sun Yat-sen University | 124 | 2023-03-09 | 2023-03-28 |
| A Study in Chronic Hepatitis B e-Antigen Negative Participants After Discontinuation of Nucleos(t)Ide Analog (NA) Treatment Entecavir (ETV), Tenofovir Disoproxil Fumarate (TDF), Tenofovir Alafenamide (TAF) - Hepatitis B, Chronic | Early Phase 1 | Withdrawn | Janssen Pharmaceutica N.V., Belgium | 2022-10-31 | 2025-06-25 | |
| Efficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B Infection Tenofovir Alafenamide 25 MG - Chronic Hepatitis B, Mother-to-child Block | Early Phase 1 | Unknown | Third Affiliated Hospital, Sun Yat-Sen University | 50 | 2020-08-01 | 2020-12-22 |
| Clinical Effects of Ganshuang Combined TDF to Treat CHB and NAFLD Chronic Hepatitis B - Chronic Hepatitis B, Nonalcoholic Fatty Liver Disease | Early Phase 1 | Completed | Sichuan Leshan Traditional Chinese Medicine Hospital | 92 | 2020-01-05 | 2022-08-31 |
Hepatitis B, Chronic (7) · Acute-On-Chronic Liver Failure (1) · Carcinoma, Hepatocellular (1) · Hepatic Encephalopathy (1) · Non-alcoholic Fatty Liver Disease (1)
Blood-Borne Infections (8) · Communicable Diseases (8) · DNA Virus Infections (8) · Digestive System Diseases (8) · Hepadnaviridae Infections (8) · Hepatitis (8) · Hepatitis, Viral, Human (8) · Infections (8) · Liver Diseases (8) · Virus Diseases (8) · Chronic Disease (7) · Disease Attributes (7) · Hepatitis, Chronic (7) · Pathologic Processes (7) · Pathological Conditions, Signs and Symptoms (7)
tenofovir alafenamide (2) · Rifaximin (1) · Tenofovir (1) · entecavir (1) · peginterferon alfa-2b (1)
Anhui Medical University (1) · Epigenic Therapeutics, Inc (1) · Grand Theravac Life Sciences (Nanjing) Co., Ltd. (1) · Janssen Pharmaceutica N.V., Belgium (1) · Ningbo No.2 Hospital (1) · Sichuan Leshan Traditional Chinese Medicine Hospital (1) · Sun Yat-sen University (1) · Third Affiliated Hospital, Sun Yat-Sen University (1)
China (7)
Jiabing Li, MD (1) · Qin Yang, MM (1)
PMID 10898704, PMID 20335583, PMID 21157444, PMID 23993913, PMID 25819304, PMID 26084406, PMID 27512927, PMID 28902040, PMID 28994123, PMID 31172417, PMID 31988585, PMID 32004593, PMID 32781201, PMID 33385299, PMID 33421158, PMID 34006193, PMID 35220659, PMID 36588741