6 recruiting, 3 completed, 2 not yet recruiting, 2 terminated. 8 Phase 2, 3 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Recruiting 4, Active not recruiting 1, Completed 1, Terminated 1, Unknown 1 |
| Phase 1 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Terminated 1 |
Follow Hematopoietic Stem Cell Transplant (HSCT): new trials by email Literature Review of Hematopoietic Stem Cell Transplant (HSCT) trials Research Report on Hematopoietic Stem Cell Transplant (HSCT)
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Peri-graft Cytokine Profile: Influence of Hematologic Disease and Donor Type Blood sampling - Myelofibrosis, Acute Leukemia | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 96 | 2026-09-15 | 2026-09-04 | |
| 26DT052; Scaling Busulfan Dose to Body Surface Area in Children Busulfan (BU) - Busulfan Pharmacokinetic Analysis, Busulfan Dosing | Phase 1 | Not yet recruiting | Children's Hospital of Philadelphia | 38 | 2026-09-01 | 2026-08-28 |
| Venetoclax Combined With Azacitidine for Consolidation Therapy in AML Ara-C Group, VEN/AZA condsolidation - Acute Myeloid Leukemia, Consolidation Therapy | Phase 2 | Recruiting | The First Affiliated Hospital of Soochow University | 216 | 2026-02-01 | 2026-08-06 |
| Ivosidenib as Post-HSCT Maintenance for AML Ivosidenib, Placebo - IDH1 Mutation, Acute Myeloid Leukemia (AML) | Phase 2 | Recruiting | Massachusetts General Hospital | 75 | 2026-01-16 | 2026-10-05 |
| PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV) PUL-042, Placebo - Hematologic Malignancies, Hematopoietic Stem Cell Transplant (HSCT) | Phase 2 | Recruiting | Pulmotect, Inc. | 100 | 2025-06-27 | 2026-08-04 |
| Study to Evaluate the Safety and Effectiveness of Withaferin A as a Treatment to Prevent GvHD in Transplant Patients SWA (standardized root extract of Withania somnifera) - Hematopoietic Stem Cell Transplant (HSCT), GVHD - Graft-Versus-Host Disease | Phase 1 / Phase 2 | Recruiting | Tata Memorial Centre | 54 | 2025-01-28 | 2026-07-24 |
| Outcome of Allogeneic Hematopoietic Stem Cell Transplantation Hematopoietic Stem Cell Transplant (HSCT) | Recruiting | The University of Hong Kong | 1000 | 2024-12-01 | 2024-11-27 | |
| Pravastatin as a Prophylactic to Reduce Endothelial Injury in Pediatric Patients With Elevated Body Mass Index Pravastatin - Hematopoietic Stem Cell Transplant (HSCT), Endothelial Injury | Phase 1 | Completed | Children's Hospital Medical Center, Cincinnati | 25 | 2023-01-27 | 2025-04-18 |
| Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation Ceftolozane / Tazobactam Injection - Pneumonia, Hematologic Malignancy | Phase 4 | Terminated | Weill Medical College of Cornell University | 17 | 2023-01-10 | 2026-01-21 |
| Safety and Efficacy of FT14 Conditioning for Allogeneic HSCT in Acute Myeloid Leukemia Fludarabine + Treosulfan - Acute Myeloid Leukaemia (AML), Hematopoietic Stem Cell Transplant (HSCT) | Phase 2 | Active not recruiting | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 82 | 2022-11-10 | 2025-11-18 |
| Ruxolitinib for Early Lung Dysfunction After Hematopoietic Stem Cell Transplant Ruxolitinib - Hematopoietic Stem Cell Transplant (HSCT), Bronchiolitis Obliterans (BO) | Phase 2 | Terminated | Children's Hospital Medical Center, Cincinnati | 7 | 2021-11-12 | 2026-04-07 |
| TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients Hematopoietic Stem Cell Transplant (HSCT), Diffuse Alveolar Hemorrhage | Recruiting | Children's Hospital Medical Center, Cincinnati | 2000 | 2021-09-08 | 2026-06-22 | |
| Efficacy of N-acetylcysteine Versus Placebo as Prophylaxis of Sinusoidal Obstruction Syndrome in Patients Undergoing Hematopoietic Stem Cell Transplantation N-acetylcysteine, Placebo - Sinusoidal Obstruction Syndrome (SOS), Hematopoietic Stem Cell Transplant (HSCT) | Phase 2 | Unknown | Instituto Brasileiro de Controle do Cancer | 80 | 2021-04-01 | 2021-03-09 |
| Developing Self-Management Interventions After HCT PNS Tracking - Hematopoietic Stem Cell Transplant (HSCT) | Completed | University of Florida | 49 | 2019-02-04 | 2021-09-09 | |
| Reduced-Intensity Conditioning (RIC) and Myeloablative Conditioning (MAC) for HSCT in AML/MDS Reduced-Intensity Conditioning Regimen, Myeloablative Conditioning Regimen - Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS) | Phase 2 | Completed | Randy Windreich | 21 | 2015-09-04 | 2024-07-16 |
Leukemia, Myeloid, Acute (4) · Hematologic Neoplasms (3) · Bronchiolitis Obliterans (2) · Myelodysplastic Syndromes (2) · Bacteremia (1) · Graft vs Host Disease (1) · Gram-Negative Bacterial Infections (1) · Hepatic Veno-Occlusive Disease (1) · Inflammation (1) · Lung Diseases, Interstitial (1) · Pneumonia (1) · Primary Myelofibrosis (1) · Pseudomonas Infections (1) · Thrombotic Microangiopathies (1)
Hematologic Diseases (9) · Hemic and Lymphatic Diseases (9) · Neoplasms (7) · Leukemia (4) · Leukemia, Myeloid (4) · Neoplasms by Histologic Type (4) · Lung Diseases (3) · Neoplasms by Site (3) · Respiratory Tract Diseases (3) · Bone Marrow Diseases (2) · Bronchial Diseases (2) · Bronchiolitis (2) · Bronchitis (2) · Lung Diseases, Obstructive (2) · Pathologic Processes (2)
Busulfan (2) · Acetylcysteine (1) · Alemtuzumab (1) · Blood Specimen Collection (1) · Hydroxyurea (1) · Melphalan (1) · Pam2CSK4 acetate and ODN M362 combination (1) · Pravastatin (1) · Thiotepa (1) · ceftolozane, tazobactam drug combination (1) · fludarabine (1) · fludarabine phosphate (1) · ivosidenib (1) · ruxolitinib (1) · treosulfan (1)
Children's Hospital Medical Center, Cincinnati (3) · Assistance Publique - Hôpitaux de Paris (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Children's Hospital of Philadelphia (1) · Instituto Brasileiro de Controle do Cancer (1) · Massachusetts General Hospital (1) · Pulmotect, Inc. (1) · Randy Windreich (1) · Tata Memorial Centre (1) · The First Affiliated Hospital of Soochow University (1) · The University of Hong Kong (1) · University of Florida (1) · Weill Medical College of Cornell University (1)
United States (9) · Brazil (1) · China (1) · Hong Kong (1) · India (1) · Italy (1)
Amir T Fathi, MD (1) · Colin Broom, MD (1) · Debra L Kelly, PhD, RN, OCN (1) · Domenico Russo, MD (1) · Harry HS Gill, MBBS, MD, FRCP, FRCPath (1) · Jamilla N Cavalcante, MD (1) · Jane Koo, MD (1) · Kasiani Myers, MD (1) · Markus Plate, MD (1) · Randy Windreich, MD (1) · Stella Davies, MBBS, PhD, MRCP (1)
PMID 10845900, PMID 11034090, PMID 12651206, PMID 12663454, PMID 18246351, PMID 18997826, PMID 19282026, PMID 21478921, PMID 21659356, PMID 22158386, PMID 22410750, PMID 22754076, PMID 22982675, PMID 23802653, PMID 25452693, PMID 26408225, PMID 26429297, PMID 26959007, PMID 27250656, PMID 29247780, PMID 29318584, PMID 29557088, PMID 30904387, PMID 31606445, PMID 31678539, PMID 32160294, PMID 32416453, PMID 32537114, PMID 32684166, PMID 33574236, PMID 33623153, PMID 34204308, PMID 3513012, PMID 36518386, PMID 38485149, PMID 40692216, PMID 41954668, PMID 42747153, PMID 5449164, PMID 9746768
R21NR017749 (1)