28 completed, 9 recruiting, 5 terminated, 4 unknown. 33 Not applicable, 6 Phase 2, 4 Phase 1, 1 Phase 3.
Follow Hearing Loss, Bilateral: new trials by email Literature Review of Hearing Loss, Bilateral trials Research Report on Hearing Loss, Bilateral
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hearing Intervention Effects on Brain and Language Development in Children With Bilateral Mild Hearing Loss Behind-the-ear (BTE) hearing aids, Hearing-care educational sessions - Hearing Loss, Bilateral | Not applicable | Not yet recruiting | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 258 | 2026-09-30 | 2026-10-02 |
| Open-label Study of SKY-GJB2 in Pediatric Subjects With GJB2-mediated Hearing Loss SKY-GJB2 - GJB2-mediated Hearing Loss, GJB2 Gene Mutation | Phase 1 / Phase 2 | Recruiting | Skylark Bio Inc. | 10 | 2026-05-28 | 2026-08-27 |
| Study of the Role of Top-down Processes in Neuronal Reorganization and Recovery From Sensory Loss: an Exploratory Behavioral and Electroencephalographic Study in Cochlear-supported Deaf Patients neurophysiological assessment, Cognitive, behavioral and quality of life assessment - Deafness, Bilateral | Not yet recruiting | University Hospital, Toulouse | 90 | 2026-03-01 | 2026-03-30 | |
| Comparative Analysis of Hearing Outcomes: Robotic vs. Manual Insertion of Cochlear Implants IotaSoft Robotic Insertion System, Manual Cochlear Implant Insertion - Sensorineural Hearing Loss, Bilateral Hearing Loss | Not applicable | Not yet recruiting | AdventHealth | 32 | 2026-01-01 | 2026-01-02 |
| Spatial Cues, Task Demands, and Auditory Selective Attention Existing bilateral cochlear implants, Normal Hearing Control - Bilateral Cochlear Implants, Hearing Loss, Bilateral | Not applicable | Recruiting | University of South Florida | 80 | 2025-10-22 | 2026-08-14 |
| Sentence Shaping - DHH Shape Coding - Hearing Loss, Bilateral | Not applicable | Recruiting | Vanderbilt University | 30 | 2025-08-28 | 2026-08-25 |
| Long-Term Outcomes of Early Communication Intervention for Deaf/Hard of Hearing Toddlers Parent-Mediated Intervention (PMI) - Hearing Loss, Bilateral | Phase 2 | Enrolling by invitation | Northwestern University | 88 | 2025-08-12 | 2026-06-01 |
| Assessing Pharmacy Technician Educational Training for the Provision of Over-the-Counter Hearing Aids in Rural Alabama and Mississippi Pharmacies Pharmacy Technician Educational Training - Bilateral Hearing Loss, Health Services Research | Not applicable | Recruiting | University of Alabama, Tuscaloosa | 144 | 2025-07-25 | 2026-08-07 |
| Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array CI632D, CI632 - Sensorineural Hearing Loss, Bilateral Hearing Loss | Recruiting | Cochlear | 19 | 2025-05-05 | 2026-07-07 | |
| Lumity CI Study - Clinical Evaluation of Next Generation Cochlear Implant Sound Processor Control cochlear implant sound processor, Next Generation Sound Processor - Ear Diseases, Hearing Loss, Bilateral | Completed | Advanced Bionics | 20 | 2025-03-10 | 2026-10-02 | |
| Speech Understanding and Listening Effort Benefits of Hearing Instruments hearing instruments - Hearing Loss, Bilateral | Not applicable | Recruiting | Sonova AG | 30 | 2025-02-05 | 2025-08-11 |
| Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy Otoferlin Gene-mediated Hearing Loss | Enrolling by invitation | Akouos, Inc. | 30 | 2024-11-11 | 2026-04-06 | |
| Comparison in New Cochlear Implanted Subjects of a Tonotopy-based Bimodal Fitting and a Conventional Fitting FS4 then TFS4 (cochlear implant), TFS4 then FS4 (cochlear implant) - Sensorineural Hearing Loss, Bilateral, Bilateral Hearing Loss | Not applicable | Recruiting | MED-EL Elektromedizinische Geräte GesmbH | 20 | 2024-11-05 | 2026-01-20 |
| Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population Cochlear™ Nucleus® System - Hearing Loss, Sensorineural, Hearing Loss, Bilateral | Not applicable | Active not recruiting | Cochlear | 50 | 2024-09-17 | 2026-06-03 |
| Performance and Hearing-related Outcomes in Adults Implanted With the CI622D Dexamethasone-eluting Cochlear Implant Compared to Those Implanted With a Standard Cochlear Implant (CI622) CI622D, CI622 - Hearing Loss, Bilateral Sensorineural, Hearing Loss, Sensorineural | Not applicable | Completed | Cochlear | 50 | 2024-06-17 | 2026-10-08 |
| A Study of Objective Fitting for Focused Multipolar Stimulation The Phoenix Research System - Hearing Loss, Bilateral | Not applicable | Completed | Cochlear | 15 | 2024-02-08 | 2026-02-09 |
| Preschool Hearing Screening Otoacoustic Emissions Testing, Pure Tone Audiometry - Hearing Loss, Hearing Disorders in Children | Not applicable | Recruiting | University of California, San Francisco | 13764 | 2023-10-01 | 2026-02-02 |
| Gene Therapy Trial for Otoferlin Gene-mediated Hearing Loss AAVAnc80-hOTOF via Akouos Delivery Device, AAVAnc80-hOTOF via Akouos Delivery Device and Precision Delivery Mechanism - Sensorineural Hearing Loss, Bilateral | Phase 3 | Recruiting | Eli Lilly and Company | 48 | 2023-09-15 | 2026-09-29 |
| A Monocentric Study Evaluating Pupillometry as an Objective Measurement for CI Fittings Pupillometry (Eve-tracking measurements) - Hearing Loss, Sensorineural, Hearing Loss, Bilateral | Not applicable | Terminated | Oticon Medical | 13 | 2023-05-02 | 2024-03-29 |
| Investigating Hearing Aid Frequency Response Curves 2 Hearing Aid - Standard Curve under Program 1, Hearing Aid - Variation #1 under Program 1, Hearing Aid - Variation #2 under Program 5 - Streaming Only - Hearing Loss, Sensorineural, Hearing Loss, Bilateral | Not applicable | Completed | Sonova AG | 25 | 2023-05-01 | 2025-03-18 |
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Hearing Loss, Sensorineural (32) · Hearing Loss (19) · Deafness (6) · Hearing Loss, Unilateral (6) · Auditory neuropathy (2) · Deafness, Autosomal Recessive 9 (2) · Hearing Loss, Conductive (2) · Hearing Loss, Mixed Conductive-Sensorineural (2) · Presbycusis (2) · Vestibular Diseases (2) · Acquired Immunodeficiency Syndrome (1) · Auditory Perceptual Disorders (1) · Confusion (1) · Deafness, Autosomal Recessive 1A (1)
Nervous System Diseases (54) · Neurologic Manifestations (54) · Pathological Conditions, Signs and Symptoms (54) · Sensation Disorders (54) · Signs and Symptoms (54) · Ear Diseases (53) · Hearing Disorders (53) · Otorhinolaryngologic Diseases (53) · Hearing Loss (35) · Behavior (3) · Communication (2) · Labyrinth Diseases (2) · Mental Disorders (2) · Neurobehavioral Manifestations (2) · Neurocognitive Disorders (2)
Cochlear Implantation (3) · Cochlear Implants (3) · Hearing Aids (2) · Audiometry, Evoked Response (1) · Audiometry, Pure-Tone (1) · Hormone Replacement Therapy (1) · Low-Level Light Therapy (1) · Mental Status and Dementia Tests (1) · Speech Perception (1) · Therapeutics (1) · golimumab (1)
Cochlear (7) · Sonova AG (5) · MED-EL Elektromedizinische Geräte GesmbH (3) · Northwestern University (3) · Oticon Medical (3) · Nottingham University Hospitals NHS Trust (2) · Radboud University Medical Center (2) · University of Iowa (2) · Aalborg University Hospital (1) · Advanced Bionics (1) · AdventHealth (1) · Akouos, Inc. (1) · Bruce J Gantz (1) · Cambridge University Hospitals NHS Foundation Trust (1) · Charles University, Czech Republic (1)
United States (29) · United Kingdom (8) · Germany (5) · Australia (3) · Canada (3) · France (3) · Netherlands (2) · Spain (2) · Taiwan (2) · Austria (1) · China (1) · Czechia (1) · Denmark (1) · New Zealand (1) · Thailand (1)
Bruce J Gantz, MD (2) · Jinyu Qian, PhD (2) · William Brassington (2) · Aaron Parkinson (1) · Alexandre Karkas, Pr (1) · Amanda Ortmann, PhD (1) · Anat V Lubetzky, PhD (1) · Antje Aschendorff (1) · Assen Koitschev, Prof. Dr. (1) · Christopher A Brown, PhD (1) · David N Cade, MD, MBA (1) · Dylan K Chan, MD, PhD (1) · Emmanuel Mylanus (1) · Esther Oh, MD, Ph.D. (1) · Hao Wu (1)
PMID 24024040, PMID 25690605, PMID 34301203, PMID 34653030, PMID 36108069, PMID 36625869, PMID 37369408, PMID 39327291, PMID 41219176, PMID 41250191, PMID 41431315
K23AG065443 (1), P01AG009524 (1), R01DC022699 (1), R21DC016265 (1), R21DC022070 (1), U01DC018920 (1)