1436 completed, 343 unknown, 153 terminated, 94 recruiting. 2186 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 2186 | Completed 1436, Unknown 343, Terminated 153, Recruiting 94, Withdrawn 73, Not yet recruiting 42, Active not recruiting 32, Enrolling by invitation 10, Suspended 3 |
Follow Glucose Metabolism Disorders: new trials by email Literature Review of Glucose Metabolism Disorders trials Research Report on Glucose Metabolism Disorders
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Assessing Trauma-related Links Between Affective and Metabolic Systems prazosin - Posttraumatic Stress Disorder, Metabolic Syndrome | Phase 4 | Not yet recruiting | VA Office of Research and Development | 70 | 2027-03-01 | 2026-10-15 |
| Insulin Icodec Initiation Strategies and Day-4 Supplemental Dosing in Type 2 Diabetes Insulin icodec - Type 2 Diabetes | Phase 4 | Not yet recruiting | Xi'an International Medical Center Hospital | 462 | 2027-01-01 | 2026-08-05 |
| Efficacy of Topical Lidocaine Gel vs. Oral Duloxetine for Painful Diabetic Peripheral Neuropathy Topical Lidocaine 2% Gel, Duloxetine (60 MG) - Painful Diabetic Neuropathy (PDN), Diabetic Neuropathies | Phase 4 | Not yet recruiting | Wah Medical college , POF hospital | 80 | 2026-12-01 | 2026-09-02 |
| Pharmacogenetics of Response to Sitagliptin (PRS) Oral Glucose Tolerance Test - Diabetes | Phase 4 | Not yet recruiting | University of Maryland, Baltimore | 400 | 2026-12-01 | 2026-02-18 |
| Heart-Kidney-Diabetes Multidisciplinary Care MOdels for CardiovascuLar Health In Patients With Chronic Kidney DiSease and Diabetes: A PragmaTIC Cluster Randomized Controlled Trial (HOLISTIC) The intervention with the MCM is Kidney-Heart GDMT initiation and titration for dose optimization (as clinically tolerated), within 4 months of enrollment in the study. - Chronic Kidney Disease, Type II Diabetes | Phase 4 | Not yet recruiting | Baim Institute for Clinical Research | 570 | 2026-12-01 | 2026-09-10 |
| Metabolic Surgery for Atrial Fibrillation Elimination Roux-en-Y Gastric Bypass or Sleeve Gastrectomy, Anti-Obesity Medication (AOM) treatment - Atrial Fibrillation, Obesity and Obesity-related Medical Conditions | Phase 4 | Not yet recruiting | Ali Aminian | 100 | 2026-11-01 | 2026-04-17 |
| Effect of SGLT2 Inhibitor on Metabolic-Dysfunction-Associated Fatty Liver Disease in Patients With Insulin Resistance Dapagliflozin 5Mg Tab, Metfomin 500 mg, Dapagliflozin (10mg Tab) - MAFLD in Prediabetes and Diabetes | Phase 4 | Not yet recruiting | Sherihan AboElyazed Mohamed Khalil | 66 | 2026-10-01 | 2026-10-23 |
| PATHS-T2D: A Recall-by-Genotype Study of Physiologic and Pharmacologic Responses Orforglipron - Diabete Type 2, Pharmacogenomic Drug Interaction | Phase 4 | Not yet recruiting | Massachusetts General Hospital | 100 | 2026-10-01 | 2026-08-31 |
| PLEASURE (Pleasing Lovers, Efficacy, Arousal, Satisfaction, and Uptake Research on Eroxon) Eroxon®, tadalafil - Type 2 Diabetes, Type 2 Diabetes (T2DM) | Phase 4 | Suspended | University of Miami | 30 | 2026-10-01 | 2026-09-28 |
| Role of Finerenone in African American Veterans With Diabetic Kidney Disease Finerenone 10 MG, Empagliflozin 10 MG - Diabetic Kidney Disease | Phase 4 | Not yet recruiting | Washington D.C. Veterans Affairs Medical Center | 30 | 2026-10-01 | 2026-08-21 |
| Mazdutide for Weight Management and Gout in Adults With Obesity Mazdutide - Gout, Obesity (BMI>30) | Phase 4 | Not yet recruiting | Hongwei Jiang | 30 | 2026-09-15 | 2026-09-17 |
| MIRACLE-T2D Montelukast Intervention for Renal, Cardiovascular and Eye Health in Type 2 Diabetes Montelukast, Placebo - Diabetes, Kidney Disease | Phase 4 | Not yet recruiting | University of Colorado, Denver | 110 | 2026-09-01 | 2026-07-06 |
| Exercise and Diabetes Interventions to Improve Brain Health in Older Adults With Type 2 Diabetes semaglutide, Moderate-Intensity Resistance Exercise, Balance and Tone (BAT) Exercise - Type 2 Diabetes, Cognitive Decline in Older Adults | Phase 4 | Not yet recruiting | Western University, Canada | 164 | 2026-09-01 | 2026-08-20 |
| Continuous Delivery of Ranibizumab Via the Port Delivery System for Proliferative Diabetic Retinopathy-related Vitreous Hemorrhage With Pars Plana Vitrectomy and Limited PRP. PDS Implant filled with 100 mg/mL Ranibizumab, Ranibizumab - Proliferative Diabetic Retinopathy, Diabetic Retinopathy | Phase 4 | Not yet recruiting | Southeast Retina Center, Georgia | 20 | 2026-09-01 | 2026-10-13 |
| Pancreatin Added to Standard Antihyperglycemic Therapy in Patients With Type 2 Diabetes Pancreatin, Placebo - Type 2 Diabetes (T2DM) | Phase 4 | Recruiting | Silesian Centre for Heart Diseases | 100 | 2026-08-01 | 2026-10-01 |
| Fecal Microbiota Transplantation for Type 2 Diabetes Mellitus and Hashimoto's Thyroiditis Fecal microbiota transplantation oral capsules - Autoimmune Thyroid Disease, Type 2 Diabetes Mellitus (T2DM) | Phase 4 | Not yet recruiting | Shen Xujun | 38 | 2026-08-01 | 2026-07-29 |
| Efficacy, Safety, and Tolerability of Tirzepatide in Real-World Conditions in Paraguay. Tirzepatide (LIPOLESS de Laboratorio de Productos Eticos C.E.I.S.A.) - Obesity, Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | Las Rías Medical Center | 160 | 2026-07-27 | 2026-05-19 |
| SGLT2i Therapy in Islet Transplantation (SIT) Empagliflozin 25 MG Oral Tablet, Empagliflozin 10 MG Oral Tablet [Jardiance] - Partial Islet Function, TPIAT | Phase 4 | Recruiting | University of Minnesota | 40 | 2026-07-21 | 2026-07-22 |
| Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance Metyrapone And Hydrocortisone, Dextrose, insulin - Shift Work Schedule, Circadian Rhythm | Phase 4 | Recruiting | Washington State University | 48 | 2026-07-16 | 2026-09-18 |
| AI-Assisted Lifestyle Intervention Versus Tirzepatide for Obesity and Newly Diagnosed Type 2 Diabetes AI-Assisted Intensive Lifestyle Intervention, Tirzepatide, Standard Lifestyle Management - Obesity, Diabetes Mellitus, Type 2 | Phase 4 | Recruiting | The First Affiliated Hospital of Anhui Medical University | 285 | 2026-07-16 | 2026-11-04 |
Showing 20 of 2186. Sign in to see all of them.
Diabetes Mellitus, Type 2 (1184) · Diabetes Mellitus (737) · Insulin Resistance (285) · Diabetes Mellitus, Type 1 (191) · Metabolic Syndrome (139) · Hypertension (135) · Obesity (131) · Hyperglycemia (81) · Coronary Artery Disease (79) · Glucose Intolerance (61) · Cardiovascular Diseases (57) · Prediabetic State (54) · Hypoglycemia (49) · Dyslipidemias (43) · Atherosclerosis (36)
Nutritional and Metabolic Diseases (2185) · Metabolic Diseases (2175) · Endocrine System Diseases (1894) · Diabetes Mellitus (1138) · Hyperinsulinism (399) · Pathological Conditions, Signs and Symptoms (356) · Cardiovascular Diseases (345) · Vascular Diseases (311) · Signs and Symptoms (228) · Immune System Diseases (212) · Autoimmune Diseases (194) · Urogenital Diseases (192) · Female Urogenital Diseases and Pregnancy Complications (168) · Nutrition Disorders (159)
Metformin (288) · Insulin Glargine (215) · Sitagliptin Phosphate (120) · dapagliflozin (116) · Insulin (106) · Pioglitazone (99) · Insulin Aspart (93) · empagliflozin (79) · Liraglutide (69) · glimepiride (65) · Exenatide (61) · Insulin Lispro (57) · Insulin Detemir (56) · Vildagliptin (52) · semaglutide (45)
Sanofi (99) · Novo Nordisk A/S (85) · Eli Lilly and Company (34) · AstraZeneca (30) · Novartis Pharmaceuticals (26) · Emory University (24) · GlaxoSmithKline (24) · Seoul National University Bundang Hospital (22) · Novartis (21) · Takeda (16) · The University of Texas Health Science Center at San Antonio (16) · Amsterdam UMC, location VUmc (14) · University of Colorado, Denver (14) · Baylor College of Medicine (13) · Steno Diabetes Center Copenhagen (13)
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