12 completed. 12 Phase 3, 2 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 12 | Completed 12 |
| Phase 2 | 2 | Completed 2 |
Follow GERD: new trials by email Literature Review of GERD trials Research Report on GERD
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Alginate vs Sucralfate for GERD Symptomatic Relief Alginate, Sucralfate - GERD | Phase 2 / Phase 3 | Completed | CMH Lahore Medical College and Institute of Dentistry | 140 | 2025-04-01 | 2026-07-15 |
| A Randomized Trial of Medical and Surgical Treatments for Patients With GERD Symptoms That Are Refractory to Proton Pump Inhibitors Nissen fundoplication, baclofen, Desipramine - GERD | Phase 3 | Completed | VA Office of Research and Development | 366 | 2012-08-13 | 2020-01-22 |
| Pantoprazole Magnesium 40 mg Versus Esomeprazole 40 mg in Patients With Erosive Gastroesophageal Reflux Disease Magnesium Pantoprazole, Magnesium Esomeprazole - GERD | Phase 3 | Completed | Takeda | 713 | 2011-08-01 | 2012-06-26 |
| Efficacy Study of Ilaprazole to Treat Erosive Esophgitis Ilaprazole, Lansoprazole - Erosive Esophagitis, GERD | Phase 3 | Completed | Il-Yang Pharm. Co., Ltd. | 292 | 2010-07-01 | 2012-01-12 |
| The Role Of Gastroesophageal Reflux Disease (GERD) in Eosinophilic Esophagitis Esomeprazole, Budesonide - Eosinophilic Esophagitis, Gastroesophageal Reflux Disease | Phase 2 / Phase 3 | Completed | Mayo Clinic | 51 | 2008-05-01 | 2016-01-14 |
| Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal Patients Esomeprazole - GERD | Phase 3 | Completed | AstraZeneca | 32 | 2006-10-01 | 2010-12-20 |
| Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD) nizatidine (axid), placebo - Gastroesophageal Reflux Disease, GERD | Phase 3 | Completed | Braintree Laboratories | 138 | 2006-08-01 | 2009-11-18 |
| Symptom Assessment in Adult Patients With Erosive GERD (Gastroesophageal Reflux Disease) or enGERD (Endoscopic-negative GERD) After Treatment With Pantoprazole (BY1023/M3-343) Pantoprazole - GERD | Phase 3 | Completed | Takeda | 628 | 2006-08-01 | 2012-05-07 |
| to Assess the Efficacy and Safety of the Probiotic E. Coli Strain M17 on Patients With GERD ProBactrix - GERD | Phase 3 | Completed | BioBalance Corporation | 60 | 2006-05-01 | 2015-01-27 |
| Esomeprazole for Prevention of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs Esomeprazole - GERD | Phase 3 | Completed | AstraZeneca | 334 | 2001-02-01 | 2011-01-21 |
| Esomeprazole for Relief of Upper Gastrointestinal Symptoms Associated With Continuous Use of NSAIDs Esomeprazole - GERD | Phase 3 | Completed | AstraZeneca | 808 | 2001-01-01 | 2011-01-24 |
| Sopran - Omeprazole Treatment Versus Surgery Omeprazole - GERD | Phase 3 | Completed | AstraZeneca | 219 | 1998-01-01 | 2011-01-24 |
Gastroesophageal Reflux (12) · Eosinophilic Esophagitis (1) · Heartburn (1)
Deglutition Disorders (12) · Digestive System Diseases (12) · Esophageal Diseases (12) · Esophageal Motility Disorders (12) · Gastrointestinal Diseases (12) · Eosinophilia (1) · Esophagitis (1) · Gastroenteritis (1) · Hematologic Diseases (1) · Hemic and Lymphatic Diseases (1) · Hypersensitivity (1) · Hypersensitivity, Immediate (1) · Immune System Diseases (1) · Leukocyte Disorders (1) · Pathological Conditions, Signs and Symptoms (1)
Esomeprazole (5) · Alginates (1) · Baclofen (1) · Budesonide (1) · Desipramine (1) · Fundoplication (1) · Lansoprazole (1) · Nizatidine (1) · Omeprazole (1) · Pantoprazole (1) · Sucralfate (1) · alginate, aluminium hydroxide, magnesium trisilicate, sodium bicarbonate drug combination (1) · ilaprazole (1)
AstraZeneca (4) · Takeda (2) · BioBalance Corporation (1) · Braintree Laboratories (1) · CMH Lahore Medical College and Institute of Dentistry (1) · Il-Yang Pharm. Co., Ltd. (1) · Mayo Clinic (1) · VA Office of Research and Development (1)
United States (5) · Germany (4) · Hungary (3) · Australia (2) · Belgium (2) · France (2) · Spain (2) · Austria (1) · Brazil (1) · Denmark (1) · Finland (1) · Israel (1) · Norway (1) · Pakistan (1) · South Korea (1)
Amy Foxx-Orenstein, D.O. (1) · Gerald Holtmann, Prof. (1) · John McGowan (1) · Kathryn Collison, MPH, MT(ASCP) (1) · Kim JinHo (1) · Marta Illueca, MD (1) · Muhammad Hafeez, MBBS (1) · Per Lundborg, MD (1) · Stuart J Spechler, MD (1)
PMID 17391505, PMID 22111863, PMID 23800403, PMID 24299323, PMID 25858519, PMID 31618539