48 completed, 1 terminated. 21 Phase 3, 16 Phase 2, 13 Phase 4, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 21 | Completed 21 |
| Phase 2 | 16 | Completed 15, Terminated 1 |
| Phase 4 | 13 | Completed 13 |
| Phase 1 | 2 | Completed 2 |
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Long-Term Safety of BLI5100 in Patients With Gastroesophageal Reflux Disease BLI5100 - Non-erosive Reflux Disease, Erosive Esophagitis | Phase 3 | Completed | Braintree Laboratories | 400 | 2023-04-05 | 2025-09-26 |
| A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Erosive Esophagitis BLI5100, PPI Control - Erosive Esophagitis | Phase 3 | Completed | Braintree Laboratories | 1250 | 2022-10-30 | 2026-06-16 |
| A Study to Evaluate the Efficacy and Safety of BLI5100 in Patients With Non-Erosive Reflux Disease BLI5100, Placebo - Non-erosive Reflux Disease | Phase 3 | Completed | Braintree Laboratories | 788 | 2022-09-06 | 2026-10-13 |
| Study 302: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy Bowel Prep - Colonoscopy | Phase 3 | Completed | Braintree Laboratories | 500 | 2020-07-13 | 2023-10-27 |
| Study 301: BLI4900 Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy Bowel Prep - Colonoscopy | Phase 3 | Completed | Braintree Laboratories | 519 | 2020-07-13 | 2023-11-07 |
| An Open-Label Preference Evaluation of BLI800 BLI800 - Colonoscopy | Phase 4 | Completed | Braintree Laboratories | 40 | 2019-09-24 | 2023-10-23 |
| A Safety and Efficacy Comparison of BLI4700 Bowel Prep Versus an FDA-approved Comparator in Adults Prior to Colonoscopy BLI4700, Polyethylene glycol bowel preparation - Colonoscopy | Phase 3 | Completed | Braintree Laboratories | 620 | 2018-01-11 | 2021-09-08 |
| A Pilot Evaluation of BLI4900 Bowel Preparation in Adult Subjects BLI4900, PEG Control - Colonoscopy | Phase 2 | Completed | Braintree Laboratories | 121 | 2017-11-09 | 2023-10-24 |
| A Safety and Efficacy Comparison of BLI4700 Bowel Preparation Versus an FDA-approved Comparator in Adult Subjects Prior to Colonoscopy BLI4700, Magnesium bowel preparation - Colonoscopy | Phase 3 | Completed | Braintree Laboratories | 389 | 2017-08-08 | 2021-09-08 |
| BLI4700-202: A Pilot Evaluation of BLI4700 Bowel Preparation in Adult Subjects BLI4700 - Colonoscopy | Phase 2 | Completed | Braintree Laboratories | 17 | 2017-02-16 | 2023-11-15 |
| A Pilot Evaluation of BLI4700 Bowel Preparation in Adult Subjects BLI4700 - Colonoscopy | Phase 1 / Phase 2 | Completed | Braintree Laboratories | 120 | 2016-08-01 | 2023-11-15 |
| An Open Label Study of Chronic Use of BLI400 Laxative in Constipated Adults BLI400 Laxative - Constipation, Chronic Idiopathic Constipation | Phase 3 | Completed | Braintree Laboratories | 330 | 2016-06-01 | 2020-07-09 |
| BLI400-302: A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults BLI400 Laxative, BLI400 Placebo - Constipation, Chronic Idiopathic Constipation | Phase 3 | Completed | Braintree Laboratories | 1020 | 2016-06-01 | 2020-07-27 |
| A Safety and Efficacy Evaluation of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation BLI801 Laxative, BLI801 Placebo - Constipation | Phase 2 / Phase 3 | Completed | Braintree Laboratories | 434 | 2016-06-01 | 2023-11-07 |
| A Safety and Efficacy Study of a Bowel Cleansing Preparation (BLI800) in Pediatric Subjects Undergoing Colonoscopy PEG-ELS, BLI800 - Colonoscopy | Phase 3 | Completed | Braintree Laboratories | 91 | 2016-06-01 | 2021-05-03 |
| A Pilot Study of BLI801 Laxative in Adults Experiencing Non-Idiopathic Constipation BLI801 Laxative - Constipation | Phase 2 | Completed | Braintree Laboratories | 16 | 2016-02-01 | 2018-09-28 |
| A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adolescent Subjects BLI400 Laxative - Constipation | Phase 2 | Completed | Braintree Laboratories | 33 | 2015-12-01 | 2020-06-26 |
| A Safety and Efficacy Evaluation of Topical Treatments for Moderate-Severe Facial Acne Vulgaris BLI1100-1, BLI1100-2, BLI1100-3 - Acne Vulgaris | Phase 2 | Completed | Braintree Laboratories | 509 | 2015-10-01 | 2017-07-28 |
| A Safety and Efficacy Evaluation of BLI400 Laxative in Constipated Adults BLI400 Laxative, Lubiprostone - Chronic Idiopathic Constipation | Phase 3 | Completed | Braintree Laboratories | 459 | 2015-05-01 | 2020-07-27 |
| A Pilot Evaluation of an Experimental BLI4600 Formulation for Bowel Preparation in Adult Patients Undergoing Colonoscopy BLI4600 bowel preparation, PEG based bowel preparation - Bowel Preparation for Colonoscopy | Phase 2 | Completed | Braintree Laboratories | 45 | 2015-01-01 | 2016-07-19 |
Showing 20 of 49. Sign in to see all of them.
Constipation (15) · Acne Vulgaris (3) · Colonic Neoplasms (2) · Non-Erosive Reflux Disease (2) · Crohn Disease (1) · Fistula (1) · Gastroesophageal Reflux (1) · Heartburn (1) · Inflammatory Bowel Diseases (1)
polyethylene glycol 3350 (4) · Bisacodyl (3) · Lubiprostone (1) · Nizatidine (1)
United States (49)
John McGowan (13) · John McGowan, MPH (13) · Jorge Herrera, MD (4) · Charles Brady, MD (2) · Leah Hollins (2) · Samuel Nurko, MD (2) · H. Paul Hatten, Jr., MD (1) · John D McGowan (1) · John D McGowan, B.S. (1) · John D McGowan, BS (1) · John Mcgowan, MPH (1) · Michael Goldstein, M.D. (1) · Russell Pelham, Ph.D. (1)
PMID 17573794, PMID 20646695, PMID 25028274, PMID 33165006, PMID 36120087, PMID 37490604, PMID 38082231