205 completed, 53 unknown, 51 recruiting, 32 terminated. 84 Phase 2, 64 Not applicable, 62 Phase 3, 30 Phase 4, 21 Phase 1.
Follow Eosinophilia: new trials by email Literature Review of Eosinophilia trials Research Report on Eosinophilia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Esophageal String Test as a Diagnostic Screening Tool for Eosinophilic Esophagitis Among Africans With Dysphagia in Mali and the United States Esophageal string test - Dysphagia, Eosinophilic Esophagitis | Not applicable | Recruiting | National Institute of Allergy and Infectious Diseases (NIAID) | 70 | 2026-11-18 | 2026-11-13 |
| Real-World Effectiveness of Depemokimab in Allergic Bronchopulmonary Aspergillosis With Severe Eosinophilic Asthma Depemokimab - Allergic Bronchopulmonary Aspergillosis, ABPA | Not applicable | Not yet recruiting | Qianfoshan Hospital | 10 | 2026-11-01 | 2026-09-24 |
| REverse LuNg Airway and Vascular RemOdeling in Asthma ReMission (ReNORM) Biologic Therapy - Asthma; Eosinophilic | Not applicable | Not yet recruiting | Western University, Canada | 200 | 2026-10-01 | 2026-07-31 |
| A Trial of Upadacitinib for Non-responsive Eosinophilic Esophagitis Upadacitinib 30mg Dose, Upadacitinib Matching Placebo - EoE, Eosinophilic Esophagitis | Phase 2 | Recruiting | University of North Carolina, Chapel Hill | 52 | 2026-09-30 | 2026-10-06 |
| Impact of Body Positioning on EndoFLIP Measurements: A Comparative Study of Supine and Left Lateral Decubitus Positions EndoFlip - Dysphagia, Esophageal Stricture | Not applicable | Recruiting | Johns Hopkins University | 25 | 2026-07-24 | 2026-08-24 |
| Roll-over Study for Participants Who Have Completed a Previous Clinical Study With Benralizumab (Fasenra) and Benefit From Continued Treatment Benralizumab - Asthma, Eosinophilic Granulomatosis With Polyangiitis (EGPA) | Phase 3 | Recruiting | AstraZeneca | 230 | 2026-07-24 | 2026-11-13 |
| Fasenra: An Asthma Study Budesonide-albuterol, Benralizumab - Eosinophilic Asthma, Severe Asthma | Phase 4 | Enrolling by invitation | Endeavor Health | 40 | 2026-07-01 | 2026-09-15 |
| Elimination Diet Strategies and Histologic Remission in Children With Eosinophilic Gastrointestinal Disorders Elimination Diet - Eosinophilic Gastrointestinal Disorders (EGID) | Recruiting | Cukurova University | 34 | 2026-07-01 | 2026-08-21 | |
| A Study of Depemokimab in Participants of 6 to 11 Years of Age Depemokimab - Asthma | Phase 3 | Recruiting | GlaxoSmithKline | 34 | 2026-06-25 | 2026-08-26 |
| Association Between Disease Severity and Clinical, Histopathological, and Eosinophilic Markers in Patients With Bullous Pemphigoid (BP-EPIC) Bullous Pemphigoid (BP) | Active not recruiting | Istanbul Training and Research Hospital | 50 | 2026-05-04 | 2026-06-16 | |
| The DiNAM-EoE-C Study: Esophageal Distensibility and Novel Assessment of Motility in Eosinophilic Esophagitis Eosinophilic Esophagitis (EoE), Dysphagia, Esophageal | Enrolling by invitation | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 25 | 2026-05-01 | 2026-07-29 | |
| Trial of Partial Enteral Nutrition With Dairy Free Diet in Eosinophilic Esophagitis Partial enteral nutrition (PEN) with dairy elimination, Dairy elimination alone - Eosinophilic Esophagitis (EoE) | Not applicable | Recruiting | Kate Farms Inc | 36 | 2026-03-18 | 2026-04-16 |
| PRospective Registry of Esophageal Motility No intervention - Esophageal Diseases, Achalasia | Recruiting | IRCCS San Raffaele | 10000 | 2026-03-09 | 2026-04-02 | |
| Comparison of Eohilia With Dupixent on Esophagus Diameter in Patients With Eosinophilic Esophagitis. Dupilumab 300 MG/2 ML Subcutaneous Solution [DUPIXENT], budesonide oral suspension - Eosinophilic Esophagitis (EoE) | Early Phase 1 | Enrolling by invitation | Mayo Clinic | 60 | 2026-02-04 | 2026-05-04 |
| A Study of KT-621 Administered Orally to Adult Participants With Moderate to Severe Eosinophilic Asthma KT-621, Placebo - Eosinophilic Asthma | Phase 2 | Recruiting | Kymera Therapeutics, Inc. | 264 | 2026-01-28 | 2026-10-06 |
| A Real-life Observational Study in Severe Eosinophilic Asthma Adult Participant Treated With Benralizumab in Italy benralizumab - Severe Eosinophilic Asthma | Recruiting | AstraZeneca | 335 | 2025-12-20 | 2026-09-18 | |
| A Multi-dose Study on the Safety and Efficacy of Self-administered Intranasal AD17002 Treatment for Eosinophilic Asthma AD17002, Formulation buffer - Eosinophilic Asthma | Phase 2 | Not yet recruiting | Advagene Biopharma Co. Ltd. | 126 | 2025-12-01 | 2025-11-26 |
| Utility of Mucosal Impedance Device in Chronic Esophageal Disorders: MuVI Esophageal mucosal impedance testing - Gerd, Eosinophilic Esophagitis | Recruiting | Medical College of Wisconsin | 50 | 2025-11-20 | 2026-07-27 | |
| A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis dupilumab - Eosinophilic Esophagitis (EoE) | Phase 3 | Recruiting | Regeneron Pharmaceuticals | 20 | 2025-11-10 | 2026-09-29 |
| A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks Vonoprazan, Placebo - Eosinophilic Esophagitis | Phase 2 | Active not recruiting | Phathom Pharmaceuticals, Inc. | 95 | 2025-10-30 | 2026-10-13 |
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Eosinophilic Esophagitis (234) · Pulmonary Eosinophilia (104) · Asthma (70) · Hypereosinophilic Syndrome (40) · Esophagitis (24) · Deglutition Disorders (19) · Eosinophilic enteropathy (18) · Gastroesophageal Reflux (16) · Esophageal Diseases (14) · Food Hypersensitivity (12) · Hypersensitivity (12) · Gastrointestinal Diseases (10) · Gastroenteritis (8) · Churg-Strauss Syndrome (7)
Hemic and Lymphatic Diseases (407) · Leukocyte Disorders (401) · Hematologic Diseases (400) · Immune System Diseases (315) · Hypersensitivity, Immediate (303) · Hypersensitivity (295) · Digestive System Diseases (230) · Gastroenteritis (226) · Gastrointestinal Diseases (225) · Esophageal Diseases (221) · Esophagitis (210) · Respiratory Tract Diseases (125) · Lung Diseases (121) · Hypereosinophilic Syndrome (102)
mepolizumab (32) · benralizumab (20) · dupilumab (19) · Fluticasone (17) · Budesonide (12) · Imatinib Mesylate (9) · reslizumab (9) · Endoscopy, Digestive System (7) · AK002 (6) · APT-1011 (5) · Antibodies, Monoclonal, Humanized (5) · Omalizumab (5) · BID protein, human (4) · Blood Specimen Collection (4) · Prednisolone (4)
Mayo Clinic (25) · AstraZeneca (24) · GlaxoSmithKline (17) · National Institute of Allergy and Infectious Diseases (NIAID) (15) · Children's Hospital Medical Center, Cincinnati (14) · Novartis Pharmaceuticals (9) · University of North Carolina, Chapel Hill (9) · University of Colorado, Denver (8) · Regeneron Pharmaceuticals (7) · Allakos Inc. (6) · Ann & Robert H Lurie Children's Hospital of Chicago (6) · Dr. Falk Pharma GmbH (5) · IRCCS San Raffaele (5) · Shire (5) · Teva Branded Pharmaceutical Products R&D, Inc. (5)
United States (230) · Italy (47) · United Kingdom (46) · Canada (45) · Germany (45) · France (41) · Spain (36) · Belgium (28) · Poland (28) · Netherlands (25) · Argentina (24) · Australia (24) · Switzerland (21) · Brazil (18) · Israel (18)
Evan S Dellon, MD, MPH (8) · Amy D Klion, M.D. (6) · Craig Paterson, MD (5) · Joshua B Wechsler, MD (5) · Marc E Rothenberg, MD, PhD (5) · Marc E. Rothenberg, M.D., Ph.D. (5) · David Katzka, MD (4) · Karthik Ravi, MD (4) · Calies Menard-Katcher, MD (3) · Evan Dellon, MD, MPH (3)
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