35 completed, 29 recruiting, 14 unknown, 5 active not recruiting. 29 Not applicable, 2 Phase 1, 2 Phase 2, 2 Phase 4, 1 Phase 3.
Follow Genetic Predisposition: new trials by email Literature Review of Genetic Predisposition trials Research Report on Genetic Predisposition
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of rs7903146 Genotype on Islet GLP-1 Production in Humans Exendin 9-39, Saline - Genetic Predisposition, Type2diabetes | Phase 2 | Not yet recruiting | Mayo Clinic | 80 | 2026-10-01 | 2026-01-30 |
| Genetic Investigation of Cancer Predisposition DNA or RNA Sequencing - Genetic Predisposition, Cancer | Not yet recruiting | The University of Texas Health Science Center at San Antonio | 100 | 2026-10-01 | 2026-01-06 | |
| Precure Targeted Accrual and Rapid Growth in Enrollment Trial Study Exposure, Environmental, Genetic Predisposition | Enrolling by invitation | Mayo Clinic | 100000 | 2026-08-07 | 2026-08-17 | |
| Outcomes of Health Care Transition for AYA With a Cancer Predisposition Readiness Assessment, Transition Outcomes Survey A, Transition Outcomes Survey B - Genetic Predisposition | Recruiting | St. Jude Children's Research Hospital | 56 | 2026-06-16 | 2026-06-18 | |
| The Preventive Risk Outreach And Cascade Testing Minimally facilitated platform, AI-powered platform - Genetic Predisposition, Family Members | Not applicable | Not yet recruiting | Stanford University | 400 | 2026-06-01 | 2026-05-14 |
| Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon Minoxidil, Hair mousse - Breast Reconstruction, Perfusion; Complications | Phase 1 | Recruiting | Duke University | 25 | 2026-03-16 | 2026-07-08 |
| Mayo Clinic Precure - Prospective Study Genetic Predisposition, Exposure, Environmental | Enrolling by invitation | Mayo Clinic | 100000 | 2026-01-19 | 2026-03-16 | |
| Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage Increase of physical activity volume and intensity with the use of a motivational smartphone application - Parkinson Disease, Prodromal Stage | Not applicable | Recruiting | Radboud University Medical Center | 600 | 2025-09-01 | 2026-10-15 |
| Genetic Information Assistant in Telegenetics Genetic Information Assistant, Telegenetics with UVA genetic counselor - Gene Mutation-Related Cancer, Genetic Predisposition | Not applicable | Recruiting | University of Virginia | 96 | 2025-04-01 | 2025-09-23 |
| Prospective Multicenter Registry of Gender, Diversity and Inclusion (GEDI) of Women With Acute Coronary Syndrome Acute Coronary Syndrome, Gender | Recruiting | IRCCS San Raffaele | 100 | 2025-01-28 | 2026-04-03 | |
| Pharmacogenomic Contributions to Trihexyphenidyl Biotransformation and Response in Children With Dystonic Cerebral Palsy Trihexyphenidyl - Pediatric Disorder, Genetic Predisposition | Phase 1 | Recruiting | Children's Mercy Hospital Kansas City | 40 | 2024-10-15 | 2026-06-24 |
| Mayo Clinic Tapestry 2.0: Applying Multi-Omics for Scientific Discovery Genetic Predisposition, Exposure, Environmental | Enrolling by invitation | Mayo Clinic | 10000 | 2024-09-05 | 2025-10-16 | |
| Developing a Whole-body MRI and Diffusion-weighted Imaging State-of-the-art Protocol: a Pilot Study Enhanced Diffusion Software - Whole Body Imaging, Cancer | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 120 | 2024-09-01 | 2024-08-01 | |
| Molecular Classification in Relation to Prevention of Endometrial Cancer Recurrence and Lifestyle Factors Endometrial Cancer, Genetic Predisposition | Recruiting | Lukas Vanek | 280 | 2024-07-15 | 2024-11-08 | |
| Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) Plasma biomarker levels - Cardiomyopathies, Genetic Predisposition | Recruiting | NHS Greater Glasgow and Clyde | 750 | 2024-06-26 | 2024-07-03 | |
| Using the EHR to Advance Genomic Medicine Across a Diverse Health System Behavioral nudge - Genetic Predisposition, Paraganglioma | Not applicable | Recruiting | University of Pennsylvania | 1000 | 2024-06-10 | 2026-08-14 |
| Genetic Susceptibility to Predict Weight Loss After Bariatric Surgery Bariatric Surgery Candidate, Obesity, Morbid | Recruiting | Institut de Recerca Biomèdica de Lleida | 6966 | 2024-03-15 | 2024-03-06 | |
| GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH oral semaglutide, Mixed Meal Tolerance Test (MMTT) - Genetic Predisposition, Metabolic Diseases | Phase 4 | Recruiting | Massachusetts General Hospital | 125 | 2024-03-12 | 2026-07-08 |
| Prostate Tissue BioBank Prostate Cancer, Genetic Predisposition | Recruiting | Abramson Cancer Center at Penn Medicine | 200 | 2024-01-01 | 2025-11-05 | |
| Barriers and Facilitators of Parent-Child Communication in Children With Cancer Predisposition Genetic Predisposition | Recruiting | St. Jude Children's Research Hospital | 125 | 2023-12-12 | 2026-04-23 |
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Genetic Predisposition to Disease (94) · Neoplasms (8) · Breast Neoplasms (6) · Rare Diseases (5) · Parkinson Disease (4) · COVID-19 (3) · Cardiomyopathies (3) · Diabetes Mellitus, Type 2 (3) · Genetic Diseases, Inborn (3) · Hypertension (3) · Prostatic Neoplasms (3) · Arrhythmias, Cardiac (2) · Atrial Fibrillation (2) · Autoimmune Diseases (2) · Crohn Disease (2)
Disease Attributes (94) · Disease Susceptibility (94) · Pathologic Processes (94) · Pathological Conditions, Signs and Symptoms (94) · Neoplasms (15) · Neoplasms by Site (13) · Cardiovascular Diseases (12) · Nutritional and Metabolic Diseases (12) · Urogenital Diseases (12) · Female Urogenital Diseases and Pregnancy Complications (9) · Metabolic Diseases (9) · Signs and Symptoms (9) · Behavior (8) · Endocrine System Diseases (8) · Nervous System Diseases (8)
Echocardiography (2) · Electrocardiography, Ambulatory (2) · Equipment and Supplies (2) · Genome-Wide Association Study (2) · High-Throughput Nucleotide Sequencing (2) · Biomarkers (1) · Blood Specimen Collection (1) · Bupropion (1) · Canrenoic Acid (1) · Capsule Endoscopy (1) · DNA (1) · Electrocardiography (1) · Fluconazole (1) · Genetic Testing (1) · Lisinopril (1)
University Hospital Tuebingen (6) · Mayo Clinic (4) · Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico (3) · University of Virginia (3) · Abramson Cancer Center at Penn Medicine (2) · Atlas Biomed (2) · Centre Georges Francois Leclerc (2) · Dana-Farber Cancer Institute (2) · IRCCS San Raffaele (2) · Scientific Institute San Raffaele (2) · St Mary's University College (2) · St. Jude Children's Research Hospital (2) · Stanford University (2) · The University of Hong Kong (2) · Afyonkarahisar Health Sciences University (1)
United States (35) · Italy (11) · Germany (8) · France (7) · United Kingdom (7) · Spain (4) · Singapore (3) · Switzerland (3) · Brazil (2) · Canada (2) · Hong Kong (2) · Israel (2) · Poland (2) · Russia (2) · Turkey (Türkiye) (2)
Konstantinos N. Lazaridis, M.D. (3) · Paolo Della Bella, MD (2) · Tobias Haack, Dr. (2) · Adam Kretowski, Prof. (1) · Adrian Vella, MD (1) · Alessandra Franzetti Pellanda, MD (1) · Allison Kurian, MD (1) · An N Dang Do, M.D. (1) · Angela R Bradbury, MD (1) · Anita Y. Kinney, R.N., Ph.D. (1) · Barbara Levy, MD (1) · Brett Phillips, MD (1)
PMID 20647424, PMID 21997396, PMID 22006311, PMID 22642073, PMID 22695330, PMID 22968341, PMID 23739212, PMID 23789315, PMID 23912809, PMID 24243635, PMID 24774647, PMID 25341628, PMID 25341889, PMID 25530085, PMID 25601634, PMID 25646330, PMID 25652150, PMID 25948786, PMID 25964024, PMID 26200236, PMID 26231011, PMID 26415764, PMID 26423388, PMID 26459321, PMID 26609520, PMID 26718413, PMID 27053381, PMID 27121890, PMID 27325848, PMID 27385614, PMID 27385763, PMID 27443514, PMID 27649801, PMID 27655442, PMID 27709117, PMID 27733407, PMID 27798346, PMID 28179222, PMID 28213204, PMID 28264723, PMID 28275101, PMID 28330907, PMID 28477794, PMID 28576134, PMID 28579156, PMID 28592516, PMID 28751763, PMID 28870219, PMID 28971986, PMID 28990589
2018 (1), K23DK131345 (1), K23NS097625 (1), R01CA129142 (1), R01DK128207 (1), R21HG011912 (1), U01CA232795 (1), U01DK112271 (1)