Gastrointestinal Diseases: Clinical Trials

1,117 trials for Gastrointestinal Diseases, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

1117 unknown. 1117 Phase 2, 177 Phase 1, 100 Phase 3.

By phase and status

PhaseTrialsStatus
Phase 21117Unknown 1117
Phase 1177Unknown 177
Phase 3100Unknown 100

Follow Gastrointestinal Diseases: new trials by email Literature Review of Gastrointestinal Diseases trials Research Report on Gastrointestinal Diseases

Trials (filtered) newest first · largest first

All 1,117 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
Node-Sparing Short-Course Radiation With CAPOX and Sintilimab for MSS Locally Advanced Colon Cancer: A Randomized, Prospective, Multicenter Study
Node-Sparing Short-Course Radiotherapy Combined with CAPOX and Sintilimab, CAPOX Chemotherapy - Microsatellite Stable (MSS) Colon Cancer, Locally Advanced Colon Cancer
Phase 2UnknownSir Run Run Shaw Hospital1402024-10-012024-09-19
BTLA Inhibitor (JS004) Combined with Toripalimab and Chemotherapy in the Perioperative Treatment of Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma
BTLA inhibitor (JS004), Toripalimab, Paclitaxel, Cisplatin - Esophageal Squamous Cell Carcinoma
Phase 2UnknownHenan Provincial People's Hospital202024-09-302024-09-19
Exploring Treatments for Children's Abdominal Pain: Comparing Trimebutine and Probiotics
Trimebutine, Lactobacillus rhamnosus, Placebo - Functional Abdominal Pain Syndrome, Functional Gastrointestinal Disorders
Phase 1 / Phase 2UnknownUniversidad de Colima822024-09-012024-08-16
Beta-Hydroxybutyrate Feasibility Treating IBD
Feasibility of beta-hydroxybutyrate supplementation to reduce inflammation in patients with Crohn's - Crohn's Disease, Inflammatory Bowel Diseases
Phase 1 / Phase 2UnknownUniversity of Texas at Austin202024-08-282024-09-19
Modified FOLFOXIRI Plus Target Therapy as a First Line Treatment for Advanced Colorectal Cancer a Prospective Phase Two Study
FOLFOXIRI Protocol - Neoplasm Malignant, Colon Cancer Stage 4
Phase 2UnknownAl-Azhar University602024-08-172024-08-28
Exploratory Study of Irinotecan Liposomes in Maintenance Therapy of Metastatic Colorectal Cancer
Irinotecan Liposome, Bevacizumab - Metastatic Colorectal Cancer
Phase 1 / Phase 2UnknownWest China Hospital202024-08-092024-08-09
A Study on the Combination of Sintilimab, Ramucirumab and Chemotherapy for First-line Treatment of Gastric Cancer With Liver Metastasis
Sintilimab, Ramucirumab, SOX/XELOX - Stomach Neoplasms
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University392024-08-012024-08-28
Prospective Phase II Study on Continuous Circumferential Reinforcement of Laparoscopic Rectal Anastomosis to Prevent Complications
Continuous Circumferential Reinforcement of the Anastomotic - Colorectal Cancer, Anastomotic Leakage
Phase 2UnknownZHI-ZHONG PAN2082024-07-202024-07-11
MRD-Guided Consolidation Therapy Following Definitive Radiotherapy in Esophageal Cancer
PD-1 monoclonal antibody consolidation therapy - Esophageal Cancer
Phase 2UnknownCancer Institute and Hospital, Chinese Academy of Medical Sciences1022024-07-162024-08-06
Adebrelimab in Combination With Apatinib and Chemotherapy/Chemoradiotherapy in Immuno-experienced Second-line ESCC.
Adebrelimab, Apatinib, Investigator chosen chemotherapy (ICC) - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital of Henan University of Science and Technology542024-07-152024-06-18
Trilaciclib Combined With Concurrent Chemoradiotherapy and Immunotherapy in the Treatment of Esophageal Cancer
Trilaciclib Injection [Cosela], Placebo - Esophageal Cancer
Phase 2UnknownThe First Affiliated Hospital with Nanjing Medical University602024-07-092024-08-26
First-Line Treatment Induced With mFOLFOX6 and HLX04 Regimen, Following Combined With Serplulimab in MSS Initially Unresectable Metastatic Colorectal Cancer
mfolfox6 and hlx04 regimen and Serplulimab, mfolfox6 and hlx04 regimen - Efficacy, Self, Safety Issues
Phase 2UnknownSir Run Run Shaw Hospital722024-07-012024-07-09
Liposomal Irinotecan Plus Bevacizumab in Irinotecan-refractory Metastatic Colorectal Cancer
Liposomal irinotecan, Bevacizumab - Colorectal Cancer
Phase 1 / Phase 2UnknownSun Yat-sen University742024-06-052024-05-30
Phase 2 Study of CU104 in Moderate-Severe Ulcerative Colitis
CU104, Placebo - Ulcerative Colitis
Phase 2UnknownCuracle Co., Ltd.452024-06-012023-06-18
Multimodal Rehabilitation on Gastric Adenocarcinoma Patients Following Radical D2 Gastrectomy
Standard SOX/XELOX adjuvant chemotherapy plus multimodal rehabilitation - Gastric Cancer
Phase 2UnknownZhejiang Cancer Hospital1382024-06-012024-05-17
Chemotherapy Plus Bevacizumab and Anti-PD-1 Followed by Induction Therapy of Chemotherapy Plus Bevacizumab
mFOLFOX6 regimen + bevacizumab + PD-1 monoclonal antibody - Metastatic Colorectal Cancer, MSS
Phase 2UnknownZhangfa Song362024-06-012024-05-16
Phase II Study of Liposomal Irinotecan for Advanced Refractory Gastric Cancer
Liposomal Irinotecan Hydrochloride - Gastric Cancer
Phase 2UnknownZhejiang Cancer Hospital502024-05-272024-05-31
Neoadjuvant Adebrelimab + DOS in Locally Advanced Resectable Gastric Cancer
Adebrelimab combined with DOS - Gastric Cancer
Phase 2UnknownTang-Du Hospital422024-05-242024-06-26
Multimodal Imaging in Rectal Cancer & Pancreatic Cancer
[111In]In-DOTA-ANTI-CEA antibody injection, SPECT/CT scan, Resection surgery - Rectal Cancer, Pancreatic Cancer
Phase 1 / Phase 2UnknownRadboud University Medical Center202024-05-022024-05-02
A Study of SC-0191 in Subjects With Metastatic Colorectal Cancer
SC0191, SC0191 + Bevacizumab, SC0191 + 5-FU/LV - Metastatic Colorectal Cancer
Phase 2UnknownTianshu Liu362024-05-012024-04-12

Showing 20 of 1117. Sign in to see all of them.

Narrower conditions

Colorectal Neoplasms (324)  ·  Stomach Neoplasms (285)  ·  Rectal Neoplasms (123)  ·  Esophageal Neoplasms (121)  ·  Esophageal Squamous Cell Carcinoma (102)  ·  Colonic Neoplasms (90)  ·  Neoplasm Metastasis (34)  ·  Colitis, Ulcerative (33)  ·  Pancreatic Neoplasms (29)  ·  Neoplasms (27)  ·  Breast Neoplasms (23)  ·  Crohn Disease (23)  ·  Gastrointestinal Neoplasms (21)  ·  Inflammatory Bowel Diseases (20)  ·  Carcinoma, Non-Small-Cell Lung (17)

Broader conditions

Digestive System Diseases (1112)  ·  Neoplasms by Site (941)  ·  Digestive System Neoplasms (937)  ·  Neoplasms (934)  ·  Gastrointestinal Neoplasms (922)  ·  Intestinal Diseases (589)  ·  Intestinal Neoplasms (475)  ·  Colonic Diseases (438)  ·  Rectal Diseases (438)  ·  Stomach Diseases (301)  ·  Esophageal Diseases (225)  ·  Head and Neck Neoplasms (207)  ·  Neoplasms by Histologic Type (166)  ·  Colorectal Neoplasms (156)

Interventions

Oxaliplatin (127)  ·  Capecitabine (107)  ·  Fluorouracil (84)  ·  Irinotecan (76)  ·  Paclitaxel (60)  ·  Cisplatin (56)  ·  S 1 (combination) (55)  ·  Bevacizumab (53)  ·  Leucovorin (51)  ·  Cetuximab (48)  ·  apatinib (44)  ·  Radiotherapy (43)  ·  Drug Therapy (40)  ·  sintilimab (40)  ·  camrelizumab (38)

Sponsors

Fudan University (44)  ·  Sun Yat-sen University (36)  ·  Chinese Academy of Medical Sciences (25)  ·  Tianjin Medical University Cancer Institute and Hospital (23)  ·  Peking University (17)  ·  Zhejiang Cancer Hospital (17)  ·  National Cancer Center, Korea (16)  ·  The First Affiliated Hospital of Zhengzhou University (14)  ·  The First Affiliated Hospital with Nanjing Medical University (14)  ·  Cancer Institute and Hospital, Chinese Academy of Medical Sciences (13)  ·  Fujian Cancer Hospital (13)  ·  Shanghai Zhongshan Hospital (13)  ·  National Taiwan University Hospital (11)  ·  Second Affiliated Hospital, Zhejiang University, School of Medicine (11)  ·  Chinese PLA General Hospital (10)

Countries

China (524)  ·  United States (81)  ·  South Korea (69)  ·  Netherlands (30)  ·  France (28)  ·  Taiwan (26)  ·  United Kingdom (26)  ·  Italy (25)  ·  Japan (25)  ·  Canada (21)  ·  Germany (21)  ·  Israel (19)  ·  Spain (19)  ·  Brazil (14)  ·  Denmark (14)

Top investigators

Feng Wang (5)  ·  Lin Shen, MD (5)  ·  Wei Peng Yong, MRCP, MB ChB (5)  ·  Cathy Hammerman, MD (3)  ·  Fuxiang Zhou, M.D. (3)  ·  Jingdong Zhang (3)  ·  Lin Shen, Professor (3)  ·  Ruihua Xu, MD, PhD (3)  ·  Se Hoon Park, MD (3)  ·  Shixiu Wu, MD (3)  ·  Yanhong Gu (3)  ·  Zhen Zhang, MD (3)  ·  Akira Tsuburaya (2)  ·  Anwaar Saeed, MD (2)  ·  Changming Huang, Professor (2)

Results publications

PMID 35623069, PMID 15273542, PMID 25447852, PMID 25514302, PMID 26313683, PMID 26755520, PMID 26884585, PMID 27480145, PMID 30348638, PMID 30642373, PMID 32306237, PMID 34725214, PMID 35219300, PMID 36657089, PMID 38421211, PMID 41379261, PMID 9146781, PMID 10089184, PMID 10091726, PMID 10400410, PMID 10744089, PMID 11091234, PMID 11223832, PMID 11231246, PMID 11239312, PMID 11247898, PMID 11248153, PMID 11289756, PMID 11413430, PMID 11491192, PMID 11712875, PMID 11754382, PMID 11813623, PMID 11914441, PMID 12187070, PMID 12196368, PMID 12378346, PMID 12510709, PMID 12756590, PMID 1334988, PMID 14578723, PMID 14759776, PMID 14967459, PMID 15083176, PMID 15131807, PMID 15175435, PMID 15496622, PMID 15668283, PMID 15711856, PMID 15783049

NIH funding

2018 (5), P30CA015083 (4), 2008 (3), 2015 (3), 2016 (3), 2005 (2), 2009 (2), 2014 (2), 2019 (2), 2023 (2), 2017 (1), K08HD052885 (1), P30CA168524 (1), R01NR010730 (1), U10CA031946 (1)