8 unknown, 5 completed, 4 terminated, 2 active not recruiting. 21 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 21 | Unknown 8, Completed 5, Terminated 4, Active not recruiting 2, Enrolling by invitation 1, Not yet recruiting 1 |
Follow Fractures, Ununited: new trials by email Literature Review of Fractures, Ununited trials Research Report on Fractures, Ununited
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Allograft vs. Autograft Nonunion Autograft, Allograft - Nonunion Fracture | Not applicable | Not yet recruiting | Wake Forest University Health Sciences | 156 | 2027-01-01 | 2026-10-26 |
| Using the Boneflo System During Orthopedic and Trauma Surgery: A Prospective Multicenter Study Intraoperative bioactivation of bone substitute materials using the Boneflo® Tissue Collector System. - Nonunion Fracture, Delayed Bone Healing | Not applicable | Completed | Universität Duisburg-Essen | 100 | 2024-07-01 | 2026-05-01 |
| G7 Freedom Constrained Vivacit-E Liners Total Hip Arthroplasty with G7 Freedom Constrained Vivacit-E Liners - Osteoarthritis, Hip, Rheumatoid Arthritis | Not applicable | Enrolling by invitation | Zimmer Biomet | 202 | 2023-05-08 | 2025-10-20 |
| Modern Methods of Treatment and Diagnosis of Patients With Injuries and Diseases of the Musculoskeletal System Autologous Mesenchymal Stromal Cells Combined with Platelet-Rich Plasma, Patient-Specific 3D-Printed Surgical Instruments - Osteoarthritis, Knee, Fractures, Ununited | Not applicable | Active not recruiting | Zaporizhzhiya State Medical University | 100 | 2023-01-13 | 2026-06-04 |
| Lumbar Fusion With Porous Versus Non-Porous Cages CONDUIT Porous Titanium Spinal Cage, PROTI 360 Titanium-Coated PEEK Spinal Cage - Spinal Fusion, Lumbar Fusion | Not applicable | Active not recruiting | Francis Farhadi | 108 | 2022-11-01 | 2026-07-06 |
| Distal Targeter vs Free-hand Distal targeting jig, Free-hand/perfect circles technique - Femur Fracture, Tibial Fractures | Not applicable | Completed | Cedars-Sinai Medical Center | 89 | 2022-10-31 | 2025-04-10 |
| Validity of the Non-union Scoring System in Management of Long Bone Fracture Non-union Improving the stability and re-fixation with different modalities, Re-fixation with biological stimulation, complex care with non-union resection and bone reconstruction - Fracture Non Union | Not applicable | Completed | Ain Shams University | 60 | 2022-02-10 | 2025-10-06 |
| Ankle Arthrodesis Nail for 2-level Pathologic Tibial Fracture osteosynthesis - Bone Metastases, Fracture Nonunion | Not applicable | Unknown | Orthopaedie Zentrum Zuerich | 1 | 2021-04-08 | 2021-08-17 |
| Intramedullary Bone Grafting for Open Tibial Shaft Fractures Intramedullary Bone Graft - Tibial Fractures, Nonunion of Fracture | Not applicable | Unknown | University of Louisville | 130 | 2020-03-26 | 2024-05-22 |
| Union Rate of Scaphoid Non-Union Fracture in Adults by Herbert Screw Versus Volar Buttress Plate Volar buttress plate, Herbert screw - Union, Scaphoid | Not applicable | Completed | Helwan University | 30 | 2020-03-01 | 2025-06-26 |
| Antibiotic Loaded Calcium Sulfate RCT Antibiotic loaded bone filler - Fracture Non Union, Infection | Not applicable | Terminated | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 100 | 2020-01-01 | 2023-12-18 |
| "Evaluation of Clinical and Radiographic Results of Pseudarthrosis of Clavicle Treated With Plaque and Screws" pseudoarthrosis of clavicle - Pseudoarthrosis of the Clavicle | Not applicable | Terminated | Istituto Ortopedico Rizzoli | 20 | 2019-07-30 | 2022-04-15 |
| Musculoskeletal Non-tumoral Pathology Quantitative Perfusion T1 mapping and MR perfusion acquisition - Osteonecrosis, Pseudarthrosis | Not applicable | Unknown | Central Hospital, Nancy, France | 400 | 2016-02-12 | 2018-08-23 |
| rhBMP-2 vs Autologous Bone Grafting for the Treatment of Non-union of the Docking Site in Tibial Bone Transport rhBMP-2 - Pseudarthrosis | Not applicable | Unknown | Universitaire Ziekenhuizen KU Leuven | 20 | 2015-07-01 | 2015-05-28 |
| Humeral Shaft Pseudoarthrosis Treated With Bone Autograft Versus Platelet Rich Plasma bone autograft of iliac crest, Platelet Rich Plasma plus bone autograft - Pseudoarthrosis | Not applicable | Completed | Universidad Autonoma de Nuevo Leon | 23 | 2014-11-01 | 2018-07-30 |
| Scaphoid Non-union and Low-intensity Pulsed Ultrasound Trial Bioventus Exogen 4000: Low-intensity pulsed ultrasound, Sham device - Nonunion of Fracture of Scaphoid Bone, Fractures, Ununited | Not applicable | Unknown | University of Calgary | 154 | 2014-09-01 | 2022-05-18 |
| Platelet-rich Plasma Combined With Conventional Surgery in the Treatment of Atrophic Nonunion of Femoral Shaft Fractures conventional surgery, autologous platelet-rich plasma - Nonunion of Fracture | Not applicable | Unknown | Qinghai University | 92 | 2014-08-01 | 2017-04-26 |
| Reamer Irrigator Aspirator (RIA) vs Autogenous Iliac Crest Bone Graft (AICBG) for the Treatment of Non-unions RIA harvesting group, AICBG harvesting group - Nonunion of Bone Graft, Fractures Non Union | Not applicable | Unknown | Unity Health Toronto | 104 | 2012-08-01 | 2019-11-27 |
| Dynesys Spinal System Post Market 522 Study Dynesys Spinal System - Degenerative Spondylolisthesis, Pseudoarthrosis | Not applicable | Terminated | Zimmer Biomet | 153 | 2012-03-01 | 2020-01-29 |
| Clinical Effectiveness of S53P4 Bioactive Glass in Treatment of Long-bone Chronic Osteomyelitis S53P4 bioactive glass (BonAlive) - Osteomyelitis, Bone Infection | Not applicable | Unknown | Academisch Ziekenhuis Maastricht | 78 | 2011-09-01 | 2021-06-30 |
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Pseudarthrosis (7) · Spondylolisthesis (3) · Osteonecrosis (2) · Tibial Fractures (2) · Ankylosis (1) · Arthritis, Rheumatoid (1) · Clavicle, Pseudarthrosis Of, Congenital (1) · Compartment Syndromes (1) · Disease (1) · Femoral Fractures (1) · Femoral Neck Fractures (1) · Hip Dislocation (1) · Hip Fractures (1) · Infections (1)
Fractures, Bone (21) · Wounds and Injuries (21) · Musculoskeletal Diseases (7) · Bone Diseases (6) · Pathological Conditions, Signs and Symptoms (4) · Joint Diseases (3) · Leg Injuries (3) · Pathologic Processes (3) · Spinal Diseases (3) · Spondylolysis (3) · Spondylosis (3) · Arthritis (2) · Necrosis (2) · Osteoarthritis (2)
Amputation, Surgical (1) · Arthroplasty, Replacement, Hip (1) · Control Groups (1) · Fracture Fixation, Internal (1) · Transplantation, Autologous (1) · Transplantation, Homologous (1)
Zimmer Biomet (2) · Academisch Ziekenhuis Maastricht (1) · Ain Shams University (1) · Cedars-Sinai Medical Center (1) · Central Hospital, Nancy, France (1) · Francis Farhadi (1) · Helwan University (1) · Istituto Ortopedico Rizzoli (1) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (1) · Orthopaedie Zentrum Zuerich (1) · Paradigm Spine (1) · Qinghai University (1) · Unity Health Toronto (1) · Universidad Autonoma de Nuevo Leon (1) · Universitaire Ziekenhuizen KU Leuven (1)
United States (7) · Canada (3) · Egypt (2) · France (1) · Germany (1) · Italy (1) · Mexico (1) · Switzerland (1) · Ukraine (1)
Aaron Nauth, MD FRCS(C) (1) · Carlos Acosta-Olivo, MD, PhD (1) · Chris Arts, PhD (1) · Craig van Horne, MD, PhD (1) · Emil Schemitsch, MD FRCS(C) (1) · Francis Farhadi, MD, PhD (1) · Gitela Gandelman (1) · Hillary Overholser (1) · Joel Batts (1) · Joseph R Hsu, MD (1) · Neil White, MD (1) · Rodolfo Zamora, MD (1) · Zichun Zhao, bachelor (1)