9 completed, 4 recruiting, 4 terminated, 3 active not recruiting. 7 Not applicable, 4 Phase 2, 2 Phase 1, 2 Phase 3, 1 Early Phase 1.
Follow Legg-Calve-Perthes Disease: new trials by email Literature Review of Legg-Calve-Perthes Disease trials Research Report on Legg-Calve-Perthes Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Screening for Biomarkers of Osteonecrosis of the Femoral Head Osteonecrosis of the Femoral Head | Recruiting | The First Affiliated Hospital of Xinxiang Medical College | 300 | 2026-04-20 | 2026-04-22 | |
| Alendronate for Osteonecrosis in Adults With Sickle Cell Disease Alendronate Sodium - Sickle Cell Disease, Sickle Cell Anemia | Phase 2 | Recruiting | University of California, Davis | 30 | 2026-03-09 | 2026-07-16 |
| Early Feasibility Study of Cartilage Defect Repair ReNew Hip Implant - Osteoarthritis, Hip, Femoroacetabular Impingement | Not applicable | Active not recruiting | Cytex Therapeutics, Inc. | 15 | 2025-11-06 | 2026-09-16 |
| Comparison of the Efficacy of Pericapsular Nerve Group Block Alone Versus Pericapsular Nerve Group Block Combined With Superior Cluneal and Superior Gluteal Nerve Blocks in Patients Undergoing Hip Surgery 15 ml Bupivacaine Hcl 0.25% injection, 20 mL bupivacaine 0.25% injection - Hip Osteoarthritis, Osteonecrosis of the Femoral Head | Not applicable | Enrolling by invitation | Ataturk University | 60 | 2025-09-01 | 2025-12-08 |
| Robotic Arm-assisted THA Vs. Conventional THA in Legg-Calvé-Perthes Disease robotic arm-assisted total hip replacement, conventional total hip replacement - Legg-Calvé-Perthes Disease | Not applicable | Enrolling by invitation | Second Affiliated Hospital, Zhejiang University, School of Medicine | 50 | 2025-07-28 | 2025-08-14 |
| Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate - Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head | Not applicable | Recruiting | Johns Hopkins University | 192 | 2025-04-01 | 2026-09-17 |
| Triple-Modal Therapy in Early-Stage Femoral Head Osteonecrosis (TM-ONFH) Core decompression, stromal vascular fraction (SVF), Hyperbaric Oxygen Therapy (HBOT) - Osteonecrosis of the Femoral Head | Completed | Ankara City Hospital Bilkent | 24 | 2025-01-22 | 2026-05-06 | |
| A Phase II Trial of RAB001 (LLP2A-Alendronate) for Steroid-Induced Early-Stage Osteonecrosis of the Femoral Head RAB001 high dose, RAB001 medium dose, RAB001 low dose - Osteonecrosis, Osteonecrosis of the Femoral Head | Phase 2 | Active not recruiting | ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. | 161 | 2024-12-24 | 2026-03-24 |
| RAB001（LLP2A-Ale） in Healthy Subjects RAB001 400 μg/kg group, RAB001 750 μg/kg group, Normal saline - Osteonecrosis of the Femoral Head | Phase 1 | Completed | ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. | 16 | 2023-02-10 | 2026-04-22 |
| PROMIS Evaluation Study PROMIS Stem - Hip Arthropathy, Osteoarthritis, Hip | Recruiting | Bezirkskrankenhaus St. Johann in Tirol | 200 | 2023-02-09 | 2023-02-21 | |
| Perthes Disease in Norway Legg Calve Perthes Disease | Active not recruiting | Oslo University Hospital | 216 | 2018-11-01 | 2025-03-18 | |
| Kineesiotaping for Patients With LCPD Kinesiotaping, Sham taping - Legg-Calve-Perthes Disease | Not applicable | Completed | Istanbul University - Cerrahpasa | 30 | 2017-09-25 | 2023-05-03 |
| Mesenchymal Stem Cells in Osteonecrosis of the Femoral Head XCEL-MT-OSTEO-ALPHA, Standard treatment - Avascular Necrosis of Femur Head | Phase 1 / Phase 2 | Completed | Banc de Sang i Teixits | 23 | 2015-05-05 | 2020-01-21 |
| The Long Term Outcome of Varus Derotational Osteotomy for Legg-Calvé-Perthes' Disease Proximal varus derotational osteotomy - Legg-Calvé-Perthes Disease | Completed | Assaf-Harofeh Medical Center | 35 | 2015-03-01 | 2016-02-08 | |
| Taperloc Complete Microplasty vs Taperloc Complete Standard: Randomized Controlled Study on Bone Mineral Density Taperloc Complete Microplasty, Taperloc Complete Standard - Osteoarthritis, Avascular Necrosis | Not applicable | Completed | Zimmer Biomet | 100 | 2013-03-01 | 2020-01-09 |
| Evaluate E1 Wear, Clinical Performance of E1 Liner in THA in Korean Patient Population E1-Hip Bearing - Osteoarthritis, Avascular Necrosis | Terminated | Zimmer Biomet | 100 | 2013-02-01 | 2025-04-02 | |
| Multicenter Prospective Cohort Study on Current Treatments of Legg-Calvé-Perthes Disease Osteotomy + Long Term Non-Weight Bearing, Osteotomy + Short Term Non-Weight Bearing, Nonoperative Observation - Legg Calve Perthes Disease | Enrolling by invitation | Texas Scottish Rite Hospital for Children | 1500 | 2012-08-01 | 2025-05-06 | |
| PHASE II CLINICAL TRIAL Prospective, Open, Nonrandomized Treatment of Osteonecrosis of the Femoral Head by the Administration of Autologous Mesenchymal Stem Cells bone marrow aspirate - Osteonecrosis of the Femoral Head | Phase 2 | Completed | Red de Terapia Celular | 3 | 2012-07-01 | 2017-03-30 |
| Study on Autologous Osteoblastic Cells Implantation to Early Stage Osteonecrosis of the Femoral Head Core decompression/PREOB® implantation, Core decompression/placebo implantation - Osteonecrosis of the Femoral Head | Phase 3 | Terminated | Bone Therapeutics S.A | 68 | 2011-11-01 | 2022-06-24 |
| Mesenchymal Stem Cell for Osteonecrosis of the Femoral Head mesenchymal stem cell infusion, bone marrow mononuclear cell infusion - Osteochondritis of the Femoral Head | Early Phase 1 | Unknown | Jianming Tan | 15 | 2009-12-01 | 2012-10-10 |
Showing 20 of 25. Sign in to see all of them.
Osteonecrosis (12) · Femur Head Necrosis (5) · Osteoarthritis (4) · Bone Diseases (3) · Musculoskeletal Diseases (3) · Osteoarthritis, Hip (3) · Arthritis, Rheumatoid (2) · Anemia, Sickle Cell (1) · Collagen Diseases (1) · Coxa Magna (1) · Femoracetabular Impingement (1) · Femoral Neck Fractures (1) · Hip Dislocation (1) · Hip Dislocation, Congenital (1)
Bone Diseases (22) · Musculoskeletal Diseases (22) · Femur Head Necrosis (20) · Pathological Conditions, Signs and Symptoms (14) · Necrosis (13) · Osteonecrosis (13) · Pathologic Processes (13) · Arthritis (7) · Joint Diseases (7) · Rheumatic Diseases (7) · Connective Tissue Diseases (4) · Skin and Connective Tissue Diseases (4) · Osteoarthritis (3) · Wounds and Injuries (3) · Autoimmune Diseases (2)
Alendronate (2) · Bupivacaine (1) · Hyperbaric Oxygenation (1) · Injections (1) · Osteotomy (1) · Population Groups (1) · Saline Solution (1) · triamcinolone hexacetonide (1)
ZhongShan LaiBo RuiChen BioMedicine Co.,Ltd. (2) · Zimmer Biomet (2) · Ankara City Hospital Bilkent (1) · Assaf-Harofeh Medical Center (1) · Ataturk University (1) · Banc de Sang i Teixits (1) · Bezirkskrankenhaus St. Johann in Tirol (1) · Bone Therapeutics S.A (1) · British Columbia Children's Hospital (1) · Cytex Therapeutics, Inc. (1) · DePuy International (1) · Istanbul University - Cerrahpasa (1) · Jianming Tan (1) · Johns Hopkins University (1) · Oslo University Hospital (1)
China (6) · United States (5) · Canada (3) · Spain (3) · Turkey (Türkiye) (3) · Austria (2) · Germany (2) · Norway (2) · South Korea (2) · Australia (1) · Brazil (1) · India (1) · Ireland (1) · Israel (1) · Italy (1)
David Wilson, Dr. (1) · Harry KW Kim, MD, MS (1) · Jianming Tan, professor (1) · Kishore Mulpuri, Dr. (1) · Kishore Mulpuri, MBBS, MS(Ortho), MHSc (1) · Klane K White, MD (1) · Lynne C Jones, PhD (1) · Michael A Mont, MD (1) · Noam Shohat, MD (1) · Oyebimpe O Adesina, MD, MS (1) · Shin Yoon Kim, PHD (1) · Stefan Huhnstock, Phd (1) · Stuart B Goodman, MD, PhD (1) · Wenjie Ren (1)
PMID 19915292, PMID 25769789, PMID 36042064, PMID 36961220
K23HL148310 (1), U01AR080993 (1)