24 completed, 8 unknown, 3 recruiting, 2 active not recruiting. 26 Not applicable, 6 Phase 2, 2 Phase 1, 1 Phase 3.
Follow Fatty Liver, Nonalcoholic: new trials by email Literature Review of Fatty Liver, Nonalcoholic trials Research Report on Fatty Liver, Nonalcoholic
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Impact of Ganoderma Lucidum on NRF2 Levels and Antioxidant Status in Metabolic Asscociated Fatty Liver Disease (GL-MAFLD-NRF2 Study) Starch Placebo, Ganoderma lucidum - MAFLD, Fatty Liver | Not applicable | Enrolling by invitation | University of Agriculture, Peshawar | 40 | 2026-04-28 | 2026-05-04 |
| Fatty Liver and Pancreatic Steatosis Fecal elastase, Ecoendoscopy, Fibroscan - Exocrine Pancreatic Insufficiency, Fatty Liver, Nonalcoholic | Not yet recruiting | Maria Marta Piskorz | 61 | 2025-09-01 | 2025-08-06 | |
| Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly Dietary supplement "Gepaktiv", UDCA (Ursodeoxycholic acid), Ademetionine - Metabolic Dysfunction-associated Fatty Liver Disease (MAFLD), Hepatomegaly | Not applicable | Recruiting | Phenomen Pharma | 90 | 2025-06-19 | 2025-07-23 |
| Lifestyle Changes in Fatty Liver; Additive Effect of Honey Intake honey intake and lifestyle changes, lifestyle changes - Fatty Liver, Nonalcoholic | Not applicable | Unknown | Cairo University | 40 | 2024-09-10 | 2024-09-19 |
| Nutritional Education Program for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) Mediterranean-diet intervention group, Standard care - Fatty Liver, Nonalcoholic, Diet, Healthy | Not applicable | Active not recruiting | Taichung Veterans General Hospital | 78 | 2024-08-08 | 2026-05-27 |
| Probiotic Supplement Versus Placebo for the Treatment of Patients With Non-alcoholic Fatty Liver Disease Probiotic, Placebo - Fatty Liver, Nonalcoholic | Not applicable | Completed | Phramongkutklao College of Medicine and Hospital | 90 | 2024-07-25 | 2025-07-25 |
| Feasibility of Immersive Virtual Reality Dietician Program in Metabolic-dysfunction Associated Steatotic Liver Disease In-person dietary weight loss counseling, Virtual reality dietary weight loss counseling - Fatty Liver, Nonalcoholic, Weight Loss | Not applicable | Completed | Milton S. Hershey Medical Center | 20 | 2024-07-01 | 2025-10-31 |
| Development of a Novel Asian Mediterranean Diet and Its Acceptability in NAFLD Fatty Liver, Nonalcoholic | Completed | Singapore Institute of Technology | 30 | 2024-04-15 | 2026-05-22 | |
| Different Exercise Modalities in the Treatment of NAFLD and Their Impact on Myokines Exercise, Motivational Interviewing - NAFLD, Nonalcoholic Fatty Liver Disease | Not applicable | Unknown | Yeditepe University | 144 | 2024-01-05 | 2024-02-26 |
| The Impact Of SGLT2 -I on Metabolic Dysfunction -Associated Steatotic Liver Disease In Patients With Type 2 Diabetes Mellitus SGLT2 inhibitor - Fatty Liver, Nonalcoholic | Phase 3 | Completed | Sohag University | 150 | 2023-11-15 | 2026-04-07 |
| Prevalence of NAFLD in T1DM Patients FibroScan - NAFLD, Type 1 Diabetes | Not applicable | Recruiting | Ziekenhuis Oost-Limburg | 138 | 2023-07-01 | 2025-07-28 |
| A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013) Efinopegdutide, Semaglutide, Placebo - Non-alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic | Phase 2 | Completed | Merck Sharp & Dohme LLC | 381 | 2023-06-23 | 2026-01-12 |
| Quantification of Hepatic Steatosis With Different Ultrasound Frequency Fatty Liver, Fatty Liver, Nonalcoholic | Unknown | Jong Keon Jang | 120 | 2023-06-08 | 2024-08-06 | |
| Evaluation of the Effects of Orange Consumption on Carbohydrate and Lipid Metabolism in Subjects With MAFLD (Metabolic Associated Fatty Liver Disease) Dietary supplementation with fresh oranges, Balanced Diet without oranges - Metabolic Disease, Fatty Liver, Nonalcoholic | Not applicable | Completed | Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis | 60 | 2023-03-01 | 2026-03-25 |
| Effects of Mindfulness Based Stress Reduction Intervention in Patients With Non-alcoholic Fatty Liver Disease Mindfulness Based Stress Reduction (MBSR) - Non-Alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic | Not applicable | Withdrawn | Virginia Commonwealth University | 2023-02-01 | 2023-02-08 | |
| Knockdown of HSD17B13 mRNA, Pharmacokinetics, Safety, and Tolerability, of AZD7503 in Non-Alcoholic Fatty Liver Disease AZD7503 Intervention - Non-alcoholic Fatty Liver Disease, Fatty Liver, Nonalcoholic | Phase 1 | Completed | AstraZeneca | 19 | 2022-08-12 | 2025-07-20 |
| Intermittent Fasting for NAFLD in Adults Time-Restricted, Intermittent Fasting - Fatty Liver, Intermittent Fasting | Not applicable | Recruiting | Massachusetts General Hospital | 25 | 2022-02-01 | 2025-12-18 |
| Impact of Time-restricted Feeding in NAFLD Intermittent fasting, DGE diet - Fatty Liver Disease, Fatty Liver | Not applicable | Unknown | Johannes Gutenberg University Mainz | 100 | 2021-10-01 | 2023-12-28 |
| Anti-diabetic Drugs and Fatty Liver Management Metformin - Fatty Liver, Nonalcoholic, Diabetes Mellitus, Type 2 | Not applicable | Unknown | Alexandria University | 120 | 2021-02-23 | 2022-01-18 |
| Evaluation the Safety and Efficacy of Cilostazol in Treatment of Patients With Fatty Liver Disease Cilostazol 50 MG, Placebo - Fatty Liver, Nonalcoholic | Phase 1 / Phase 2 | Withdrawn | Sadat City University | 2021-02-16 | 2025-07-14 |
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Non-alcoholic Fatty Liver Disease (41) · Fatty Liver (15) · Diabetes Mellitus, Type 2 (9) · Obesity (4) · Diabetes Mellitus (3) · Liver Diseases (3) · Digestive System Diseases (2) · Insulin Resistance (2) · Intermittent Fasting (2) · Liver Cirrhosis (2) · Metabolic Diseases (2) · Diabetes Mellitus, Type 1 (1) · Endocrine System Diseases (1) · Exocrine Pancreatic Insufficiency (1) · Fasting (1)
Digestive System Diseases (39) · Liver Diseases (38) · Fatty Liver (26) · Nutritional and Metabolic Diseases (17) · Glucose Metabolism Disorders (13) · Metabolic Diseases (13) · Endocrine System Diseases (10) · Pathological Conditions, Signs and Symptoms (9) · Diabetes Mellitus (8) · Body Weight (5) · Signs and Symptoms (5) · Behavior (4) · Nutrition Disorders (4) · Overnutrition (4) · Overweight (4)
Probiotics (2) · empagliflozin (2) · Cilostazol (1) · Diet, Ketogenic (1) · Diet, Mediterranean (1) · Dietary Supplements (1) · Exercise (1) · IONIS-ANGPTL3-LRx (1) · Liraglutide (1) · Low-Level Light Therapy (1) · Metformin (1) · Mindfulness-Based Stress Reduction (1) · Motivational Interviewing (1) · Nutrition Assessment (1) · S-Adenosylmethionine (1)
Maastricht University Medical Center (3) · Cairo University (2) · Johannes Gutenberg University Mainz (2) · Massachusetts General Hospital (2) · Virginia Commonwealth University (2) · Ziekenhuis Oost-Limburg (2) · Akcea Therapeutics (1) · Alexandria University (1) · AstraZeneca (1) · Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis (1) · Chinese University of Hong Kong (1) · Chonbuk National University Hospital (1) · Federal University of Health Science of Porto Alegre (1) · German Diabetes Center (1) · HighTide Therapeutics (Hong Kong) Limited (1)
United States (11) · Egypt (5) · Germany (4) · South Korea (4) · Belgium (3) · Netherlands (3) · Canada (2) · China (2) · Hong Kong (2) · Israel (2) · Italy (2) · Singapore (2) · Taiwan (2) · Thailand (2) · Turkey (Türkiye) (2)
Adrian Di Bisceglie, MD,FACP,FAASLD (1) · Ali MA Ismail, lecturer (1) · Arun J Sanyal, MD (1) · Bibi Hajira, PhD (1) · Cristiane V Tovo, PHD (1) · Ebtesam Nabil, doctoral (1) · Hubert C Chen, MD (1) · Ina Bergheim, PhD (1) · Jeong Min Lee (1) · JongKeon Jang, Professor (1) · Justin Tondt, MD (1) · Kathleen Corey, MD (1) · Kyungeh An, PhD (1)
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UL1TR000058 (1)