5 completed, 2 recruiting, 2 withdrawn, 1 terminated. 11 Phase 3, 3 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 11 | Completed 5, Recruiting 2, Withdrawn 2, Terminated 1, Unknown 1 |
| Phase 2 | 3 | Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Essential Tremor: new trials by email Literature Review of Essential Tremor trials Research Report on Essential Tremor
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Essential 3 - Decentralized, Phase 3 Study Evaluating the Safety and Efficacy of Ulixacaltamide in Essential Tremor (ET) 60 mg ulixacaltamide, Placebo - Essential Tremor | Phase 3 | Recruiting | Praxis Precision Medicines | 1000 | 2023-11-02 | 2026-10-06 |
| A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor SAGE-324 - Essential Tremor | Phase 2 / Phase 3 | Terminated | Sage Therapeutics | 97 | 2022-06-03 | 2025-08-01 |
| [18F] LBT-999 PET Compared to [123I]-FP/CIT SPECT to Distinguish Between Parkinson's Diseases and Essential Tremor SPECT, PET - Parkinson Disease, Essential Tremor | Phase 3 | Completed | GE Healthcare | 152 | 2021-12-01 | 2025-11-17 |
| Bilateral Essential Tremor Treatment With Gamma Knife Gamma Knife VIM thalamotomy - Essential Tremor | Phase 2 / Phase 3 | Recruiting | Université de Sherbrooke | 50 | 2021-06-08 | 2021-11-17 |
| A Study to Evaluate the Diagnostic Efficacy of DaTSCAN™ Ioflupane (123I) Injection in Single Photon Emission Computed Tomography (SPECT) for the Diagnosis of Parkinsonian Syndrome (PS) in Chinese Patients DaTSCAN™ Ioflupane (123I) Injection - Parkinsonian Syndrome, Parkinson Disease(PD) | Phase 3 | Completed | GE Healthcare | 172 | 2020-06-28 | 2023-10-16 |
| Efficacy of Pramipexole Extended Release in the Treatment of Essential Tremor pramipexole, placebo - Essential Tremor | Phase 3 | Withdrawn | University of Pecs | 2017-12-01 | 2017-05-08 | |
| Two Separate But Identical Studies Evaluating the Safety and Efficacy of ALTROPANE® in the Use of SPECT Imaging for Upper Extremity Tremor 123 I - ALTROPANE® - Parkinsonian Syndromes | Phase 3 | Unknown | Alseres Pharmaceuticals, Inc | 240 | 2010-07-01 | 2010-02-03 |
| Dexmedetomidine Effects on Microelectrode Recording in Deep Brain Stimulation Dexmedetomidine Hydrochloride Infusion, Normal Saline - Parkinson's Disease, Essential Tremor | Phase 2 / Phase 3 | Withdrawn | Vanderbilt University | 2008-01-01 | 2014-07-01 | |
| Efficacy and Safety of F-18 FPCIT PET in Parkinson's Disease and Essential Tremor Patients PET/CT, F-18 FPCIT - Parkinson's Disease | Phase 3 | Completed | Asan Medical Center | 78 | 2006-11-01 | 2016-01-13 |
| A Comparison of the Efficacy and Safety of Topiramate Versus Placebo in Treating Tremor of Unknown Cause. topiramate - Essential Tremor | Phase 3 | Completed | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | 223 | 2001-10-01 | 2011-06-10 |
| Novel Therapies for Essential Tremor treatments for essential tremor - Essential Tremor | Phase 3 | Completed | US Department of Veterans Affairs | 2000-10-01 | 2009-01-21 |
Parkinson Disease (5) · Tremor (3) · Movement Disorders (2) · Parkinsonian Disorders (2) · Central Nervous System Diseases (1) · Disease (1) · Dyskinesias (1) · Dystonia (1) · Multiple System Atrophy (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Supranuclear Palsy, Progressive (1)
Central Nervous System Diseases (10) · Nervous System Diseases (10) · Movement Disorders (9) · Basal Ganglia Diseases (5) · Brain Diseases (5) · Neurodegenerative Diseases (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Synucleinopathies (5) · Neurologic Manifestations (4) · Dyskinesias (3) · Parkinsonian Disorders (3) · Autonomic Nervous System Diseases (1) · Cranial Nerve Diseases (1) · Eye Diseases (1)
Dexmedetomidine (1) · Injections (1) · Iodine-123 (1) · Magnetic Resonance Spectroscopy (1) · Pramipexole (1) · Saline Solution (1) · Therapeutics (1) · Topiramate (1) · ioflupane (1)
GE Healthcare (2) · Alseres Pharmaceuticals, Inc (1) · Asan Medical Center (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · Praxis Precision Medicines (1) · Sage Therapeutics (1) · US Department of Veterans Affairs (1) · University of Pecs (1) · Université de Sherbrooke (1) · Vanderbilt University (1)
United States (5) · Canada (1) · China (1) · France (1) · Hungary (1) · South Korea (1)
Fredricka Martin, Ph.D. (1) · Jae Seung Kim, MD (1) · Joseph Neimat, M.D. (1) · Norbert Kovacs, MD, PhD (1)